Structure-based design of nonpeptide inhibitors specific for the human immunodeficiency virus 1 protease - Wikidata - awgldk - TriplyDB

Structure-based design of nonpeptide inhibitors specific for the human immunodeficiency virus 1 protease

Structure-based design of nonpeptide inhibitors specific for the human immunodeficiency virus 1 protease

http://www.wikidata.org/entity/Q28331230

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Bile pigments as HIV-1 protease inhibitors and their effects on HIV-1 viral maturation and infectivity in vitro Flexible ligand docking using conformational ensembles Harvesting candidate genes responsible for serious adverse drug reactions from a chemical-protein interactome The aspartic proteases Protein binding of human immunodeficiency virus protease inhibitor KNI-272 and alteration of its in vitro antiretroviral activity in the presence of high concentrations of proteins CGP 53437, an orally bioavailable inhibitor of human immunodeficiency virus type 1 protease with potent antiviral activity Accurate reproduction of 161 small-molecule complex crystal structures using the EUDOC program: expanding the use of EUDOC to supramolecular chemistry Optimized hydrophobic interactions and hydrogen bonding at the target-ligand interface leads the pathways of drug-designing Identification of inhibitors against Mycobacterium tuberculosis thiamin phosphate synthase, an important target for the development of anti-TB drugs Identification of Small-Molecule Inhibitors against Meso-2, 6-Diaminopimelate Dehydrogenase from Porphyromonas gingivalis Benchmarking sets for molecular docking Decoys for docking Computational drug repositioning: from data to therapeutics.Automated docking and the search for HIV protease inhibitors.Conformationally homogeneous heterocyclic pseudotetrapeptides as three-dimensional scaffolds for rational drug design: receptor-selective somatostatin analogues.The early years of retroviral protease crystal structures.Renin modulates HIV replication in T cells Anti-HIV activity of medicinal herbs: usage and potential development.In silico study and validation of phosphotransacetylase (PTA) as a putative drug target for Staphylococcus aureus by homology-based modelling and virtual screening.Peptide interactions with G-protein coupled receptors.Antiretroviral therapy: strategies beyond single-agent reverse transcriptase inhibition.Heme and I.Antiviral therapy: current concepts and practices Structure-based inhibitor design by using protein models for the development of antiparasitic agents.Crystal structures of a multidrug-resistant human immunodeficiency virus type 1 protease reveal an expanded active-site cavity.Analysis of the structure of chemically synthesized HIV-1 protease complexed with a hexapeptide inhibitor. Part I: Crystallographic refinement of 2 A data.Expression of virus-encoded proteinases: functional and structural similarities with cellular enzymes Evaluation of DOCK 6 as a pose generation and database enrichment tool.Chemical-protein interactome and its application in off-target identification.Drug repositioning for orphan diseases.Rational design of CCR2 antagonists: a survey of computational studies.Drug Metabolism in Preclinical Drug Development: A Survey of the Discovery Process, Toxicology, and Computational Tools.A model of interaction between nicotinamide adenine dinucleotide phosphate (NADPH) oxidase and apocynin analogues by docking method.Cellular aspartyl proteases promote the unconventional secretion of biologically active HIV-1 matrix protein p17.Molecular docking towards drug discovery.Identification of HIV-1 integrase inhibitors based on a four-point pharmacophore.Homology modeling and virtual screening approaches to identify potent inhibitors of VEB-1 β-lactamase Synthetic "interface" peptides alter dimeric assembly of the HIV 1 and 2 proteases.Ligand solvation in molecular docking.Stereoselective synthesis of O-tosyl azabicyclic derivatives via aza Prins reaction of endocyclic N-acyliminium ions: application to the total synthesis of (±)-epi-indolizidine 167B and 209D.

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P2860

Structure-based design of nonpeptide inhibitors specific for the human immunodeficiency virus 1 protease

http://www.wikidata.org/entity/Q28331230

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1990 nî lūn-bûn

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1990 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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1990 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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1990年の論文

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1990年論文

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1990年論文

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1990年論文

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1990年論文

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1990年論文

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1990年论文

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Structure-based design of nonp ...... unodeficiency virus 1 protease

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PNAS.87.17.6644

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Proceedings of the National Academy of Sciences of the United States of America

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Structure-based design of nonp ...... unodeficiency virus 1 protease

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C S Craik

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D L DeCamp

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G L Seibel

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I D Kuntz

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J C Alvarez

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L M Babé

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P R Ortiz de Montellano

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P S Furth

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R L DesJarlais

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P2860

Carcinogens are mutagens: a simple test system combining liver homogenates for activation and bacteria for detection

Active human immunodeficiency virus protease is required for viral infectivity

Cleavage of structural proteins during the assembly of the head of bacteriophage T4

Conserved folding in retroviral proteases: crystal structure of a synthetic HIV-1 protease

Three-dimensional structure of aspartyl protease from human immunodeficiency virus HIV-1

Structure of complex of synthetic HIV-1 protease with a substrate-based inhibitor at 2.3 A resolution

Complete nucleotide sequence of the AIDS virus, HTLV-III

Areas, volumes, packing and protein structure

Inhibition of HIV-1 protease in infected T-lymphocytes by synthetic peptide analogues

In vitro inhibition of HIV-1 proteinase by cerulenin

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6644-8

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