Adenosine deaminase deficiency increases thymic apoptosis and causes defective T cell receptor signaling - Wikidata - awgldk - TriplyDB

Adenosine deaminase deficiency increases thymic apoptosis and causes defective T cell receptor signaling

Adenosine deaminase deficiency increases thymic apoptosis and causes defective T cell receptor signaling

http://www.wikidata.org/entity/Q28343421

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The molecular pathology of primary immunodeficiencies Inborn errors of the development of human natural killer cells Adenosine Deaminase Deficiency - More Than Just an Immunodeficiency Purinergic signalling in endocrine organs Autoimmune dysregulation and purine metabolism in adenosine deaminase deficiency.Adenosine deaminase deficient severe combined immunodeficiency presenting as atypical haemolytic uraemic syndrome.CD73 on tumor cells impairs antitumor T-cell responses: a novel mechanism of tumor-induced immune suppression Adenosine A2A receptor activation protects CD4+ T lymphocytes against activation-induced cell death.Mapping quantitative trait loci for T lymphocyte subpopulations in peripheral blood in swine.Immune cell regulation by autocrine purinergic signalling.Carrier frequency of a nonsense mutation in the adenosine deaminase (ADA) gene implies a high incidence of ADA-deficient severe combined immunodeficiency (SCID) in Somalia and a single, common haplotype indicates common ancestry.Modulation of neuroimmunity by adenosine and its receptors: metabolism to mental illness Defective B cell tolerance in adenosine deaminase deficiency is corrected by gene therapy Restoring balance to B cells in ADA deficiency Altered intracellular and extracellular signaling leads to impaired T-cell functions in ADA-SCID patients.Transcriptome analysis of murine thymocytes reveals age-associated changes in thymic gene expression Restoration of adenosine deaminase-deficient human thymocyte development in vitro by inhibition of deoxynucleoside kinases Evaluation of Serum Adenosine Deaminase in Cystic Fibrosis Patients in an Iranian Referral Hospital.Development of gene therapy: potential in severe combined immunodeficiency due to adenosine deaminase deficiency.Elevated IgE and atopy in patients treated for early-onset ADA-SCID.How I treat ADA deficiency.Preclinical demonstration of lentiviral vector-mediated correction of immunological and metabolic abnormalities in models of adenosine deaminase deficiency.Hypoxia induces T-cell apoptosis by inhibiting chemokine C receptor 7 expression: the role of adenosine receptor A(2).Insights into NK cell biology from human genetics and disease associations.Regulation of lymphocyte function by adenosine.Extracellular adenosine metabolism in immune cells in melanoma.Inborn errors of metabolism underlying primary immunodeficiencies.Inhibition of Transient Receptor Potential Channel Mucolipin-1 (TRPML1) by Lysosomal Adenosine Involved in Severe Combined Immunodeficiency Diseases.IL-13 and adenosine: partners in a molecular dance?Adenosine and lymphocyte regulation.A deficiency in nucleoside salvage impairs murine lymphocyte development, homeostasis, and survival.Multiparametric Whole Blood Dissection: A one-shot comprehensive picture of the human hematopoietic system.Viramidine demonstrates better safety than ribavirin in monkeys but not rats.Adenosine Deaminase (ADA)-Deficient Severe Combined Immune Deficiency (SCID): Molecular Pathogenesis and Clinical Manifestations.Hematopoietic stem cell gene therapy for adenosine deaminase-deficient severe combined immunodeficiency leads to long-term immunological recovery and metabolic correction.Biogenic synthesis of copper oxide nanoparticles using olea europaea leaf extract and evaluation of their toxicity activities: An in vivo and in vitro study.Raised serum adenosine deaminase level in nonobese type 2 diabetes mellitus.Adenosine deaminase deficiency: a review.

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Adenosine deaminase deficiency increases thymic apoptosis and causes defective T cell receptor signaling

http://www.wikidata.org/entity/Q28343421

description

2001 nî lūn-bûn

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2001 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2001 թվականի հուլիսին հրատարակված գիտական հոդված

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2001年の論文

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2001年論文

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2001年論文

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2001年論文

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2001年論文

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2001年論文

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2001年论文

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Adenosine deaminase deficiency ...... tive T cell receptor signaling

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Adenosine deaminase deficiency ...... tive T cell receptor signaling

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Adenosine deaminase deficiency ...... tive T cell receptor signaling

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Adenosine deaminase deficiency ...... tive T cell receptor signaling

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Adenosine deaminase deficiency ...... tive T cell receptor signaling

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Adenosine deaminase deficiency ...... tive T cell receptor signaling

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Adenosine deaminase deficiency ...... tive T cell receptor signaling

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Adenosine deaminase deficiency ...... tive T cell receptor signaling

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Adenosine deaminase deficiency ...... tive T cell receptor signaling

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Journal of Clinical Investigation

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Adenosine deaminase deficiency ...... tive T cell receptor signaling

@en

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M R Blackburn

http://www.w3.org/2001/XMLSchema#string

M V Sitkovsky

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P T Smith

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R E Kellems

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S G Apasov

http://www.w3.org/2001/XMLSchema#string

P2860

Chemokine receptor responses on T cells are achieved through regulation of both receptor expression and signaling

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

Adenosine deaminase-deficient mice generated using a two-stage genetic engineering strategy exhibit a combined immunodeficiency

Tissue-specific rescue suggests that placental adenosine deaminase is important for fetal development in mice

Role of A2a extracellular adenosine receptor-mediated signaling in adenosine-mediated inhibition of T-cell activation and expansion

Ontogeny of adenosine deaminase in the mouse decidua and placenta: immunolocalization and embryo transfer studies

Metabolites from apoptotic thymocytes inhibit thymopoiesis in adenosine deaminase-deficient fetal thymic organ cultures

Metabolic and immunologic consequences of limited adenosine deaminase expression in mice

A(2A) receptor dependent and A(2A) receptor independent effects of extracellular adenosine on murine thymocytes in conditions of adenosine deaminase deficiency

The extracellular versus intracellular mechanisms of inhibition of TCR-triggered activation in thymocytes by adenosine under conditions of inhibited adenosine deaminase

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131-41

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scholarly article

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4060110

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10.1172/JCI10360

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10.1172/JCI200110360

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1

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108

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11906401

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11435465

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Adenosine deaminase

Fc receptor, IgE, low affinity II, alpha polypeptide

Complement receptor type 2

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209335

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