Diltiazem causes open channel block of recombinant 5-HT3 receptors

Diltiazem causes open channel block of recombinant 5-HT3 receptors

Item
http://www.wikidata.org/entity/Q28343529
5-HT3 receptorsOpen probability of homomeric murine 5-HT3A serotonin receptors depends on subunit occupancyMinimal structural rearrangement of the cytoplasmic pore during activation of the 5-HT3A receptor.The 5-HT3B subunit confers spontaneous channel opening and altered ligand properties of the 5-HT3 receptor.Binding sites for bilobalide, diltiazem, ginkgolide, and picrotoxinin at the 5-HT3 receptor.The antimalarial drugs quinine, chloroquine and mefloquine are antagonists at 5-HT3 receptors.Modular design of Cys-loop ligand-gated ion channels: functional 5-HT3 and GABA rho1 receptors lacking the large cytoplasmic M3M4 loopThe L293 residue in transmembrane domain 2 of the 5-HT3A receptor is a molecular determinant of allosteric modulation by 5-hydroxyindole.Lamotrigine, an antiepileptic drug, inhibits 5-HT3 receptor currents in NCB-20 neuroblastoma cells.Discriminating between 5-HT₃A and 5-HT₃AB receptorsCo-expression of the 5-HT3B serotonin receptor subunit alters the biophysics of the 5-HT3 receptor.Conversion of the ion selectivity of the 5-HT(3a) receptor from cationic to anionic reveals a conserved feature of the ligand-gated ion channel superfamily.Structural and electrostatic properties of the 5-HT3 receptor pore revealed by substituted cysteine accessibility mutagenesis.Tricyclic antidepressant amitriptyline inhibits 5-hydroxytryptamine 3 receptor currents in NCB-20 cells
P2860

Diltiazem causes open channel block of recombinant 5-HT3 receptors

Item
http://www.wikidata.org/entity/Q28343529
description
1999 nî lūn-bûn
@nan
1999 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Diltiazem causes open channel block of recombinant 5-HT3 receptors
@ast
Diltiazem causes open channel block of recombinant 5-HT3 receptors
@en
Diltiazem causes open channel block of recombinant 5-HT3 receptors
@nl
type
label
Diltiazem causes open channel block of recombinant 5-HT3 receptors
@ast
Diltiazem causes open channel block of recombinant 5-HT3 receptors
@en
Diltiazem causes open channel block of recombinant 5-HT3 receptors
@nl
prefLabel
Diltiazem causes open channel block of recombinant 5-HT3 receptors
@ast
Diltiazem causes open channel block of recombinant 5-HT3 receptors
@en
Diltiazem causes open channel block of recombinant 5-HT3 receptors
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P932
P356
P1433
P1476
Diltiazem causes open channel block of recombinant 5-HT3 receptors
@en
P2093
P2860
P304
P31
P356
10.1111/J.1469-7793.1999.0713N.X
P407
P433
P478
P577
P5875
P698
P932