Structural features of the ligand-binding domain of the serotonin 5HT3 receptor
about
A structural and mutagenic blueprint for molecular recognition of strychnine and d-tubocurarine by different cys-loop receptors5-HT3 receptorsFunctional group interactions of a 5-HT3R antagonistIdentification of critical residues in loop E in the 5-HT3ASR binding siteFunctional reconstitution and characterization of recombinant human alpha 1-glycine receptors.The binding orientations of structurally-related ligands can differ; A cautionary noteMapping spatial relationships between residues in the ligand-binding domain of the 5-HT3 receptor using a molecular rulerBinding interactions of antagonists with 5-hydroxytryptamine3A receptor models.The binding characteristics and orientation of a novel radioligand with distinct properties at 5-HT3A and 5-HT3AB receptorsTherapeutics of 5-HT3 receptor antagonists: current uses and future directions.Novel therapies in the treatment of irritable bowel syndrome.5-HT(3) receptors.The auspicious role of the 5-HT3 receptor in depression: a probable neuronal target?The structural basis of function in Cys-loop receptors.Cysteine modification reveals which subunits form the ligand binding site in human heteromeric 5-HT3AB receptors.Aromatic Residues {epsilon}Trp-55 and {delta}Trp-57 and the Activation of Acetylcholine Receptor Channels.Prediction of 5-HT3 receptor agonist-binding residues using homology modeling.The role of tyrosine residues in the extracellular domain of the 5-hydroxytryptamine3 receptor.Characterization of the ligand-binding site of the serotonin 5-HT3 receptor: the role of glutamate residues 97, 224, AND 235.Tyrosine 62 of the gamma-aminobutyric acid type A receptor beta 2 subunit is an important determinant of high affinity agonist binding.Structure-activity relationships of quinoxaline-based 5-HT3A and 5-HT3AB receptor-selective ligands.The role of tryptophan residues in the 5-Hydroxytryptamine(3) receptor ligand binding domain.Design, synthesis, and structure-activity relationships of highly potent 5-HT₃ receptor ligands.Deletion of the 5-HT(3A)-receptor subunit blunts the induction of cocaine sensitization.Contributions of Torpedo nicotinic acetylcholine receptor gamma Trp-55 and delta Trp-57 to agonist and competitive antagonist function.Different residues in the GABA(A) receptor alpha 1T60-alpha 1K70 region mediate GABA and SR-95531 actions.
P2860
Q21145775-716EAAC9-A850-46EA-92FF-320A5C19AA00Q24648000-ECFAE247-7E79-4936-B691-407625BA0BEDQ24796240-70BA4BC5-F0DE-4C45-A3A2-4B27E92DE60BQ24796667-790DE0EA-5A65-43B4-ACE9-2FC4B14508D6Q31807464-1DD0B727-6CB1-4A1B-982B-D4D43BCA928AQ33777929-9B3D5188-D06A-4A8D-896B-FDC9650D39A1Q33820930-DFFDEB61-5678-49F5-91E9-9F32995094E3Q34277790-DCC68F07-4CC9-4BEA-99F3-8F8A9591DDF7Q34451614-4B3D892B-C4C2-4721-9B17-69262B31E23DQ35011413-2566401B-3823-4CC7-B1CA-C6E957AF3344Q35094684-A3B89A2C-CBFB-4898-B512-F33AE6F517CFQ36418782-539A7E9D-0E67-47F5-A800-95E36F66887BQ37685759-472DA759-5953-413D-8AC8-1930A7360F43Q37789790-6CB5C877-3192-4AA1-B2E7-7D43B7BC6C34Q38566791-832D4063-82B6-4558-9F21-B24112FB8ACBQ39890497-CBEFA8F3-1280-4D8C-B096-DC87B3D78A5AQ40233436-34994321-152C-44DB-B7AA-CD4316B757CDQ40582728-1A5021A8-8C7F-4900-9C7D-E00CC4F1338BQ40661035-D8C04D40-D642-40B2-B9A8-66D9EA416E9DQ40881885-75ECE34E-BB88-4538-BBFC-E80BF95E8392Q40883648-AF60B367-963C-439C-98F7-D43DB58BE694Q40899364-2B385B4F-BD25-4A5D-8448-7232675A3F03Q41738282-6D82B4B5-6091-4DD1-A728-16859695F97CQ41831497-28AB55D2-EF87-4083-86E0-3ADDE0329127Q43509065-B6477A3B-FF9A-4474-AA20-6F1EEFADCE4AQ43918728-16AFBD2F-3817-48D4-AC29-907BFCEF8DC2
P2860
Structural features of the ligand-binding domain of the serotonin 5HT3 receptor
description
1999 nî lūn-bûn
@nan
1999 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Structural features of the ligand-binding domain of the serotonin 5HT3 receptor
@ast
Structural features of the ligand-binding domain of the serotonin 5HT3 receptor
@en
Structural features of the ligand-binding domain of the serotonin 5HT3 receptor
@nl
type
label
Structural features of the ligand-binding domain of the serotonin 5HT3 receptor
@ast
Structural features of the ligand-binding domain of the serotonin 5HT3 receptor
@en
Structural features of the ligand-binding domain of the serotonin 5HT3 receptor
@nl
prefLabel
Structural features of the ligand-binding domain of the serotonin 5HT3 receptor
@ast
Structural features of the ligand-binding domain of the serotonin 5HT3 receptor
@en
Structural features of the ligand-binding domain of the serotonin 5HT3 receptor
@nl
P2093
P2860
P356
P1476
Structural features of the ligand-binding domain of the serotonin 5HT3 receptor
@en
P2093
P2860
P304
P356
10.1074/JBC.274.9.5537
P407
P577
1999-02-26T00:00:00Z