The role of tryptophan residues in the 5-Hydroxytryptamine(3) receptor ligand binding domain.
about
5-HT3 receptorsFunctional group interactions of a 5-HT3R antagonistIdentification of critical residues in loop E in the 5-HT3ASR binding sitePrinciples of agonist recognition in Cys-loop receptorsThe binding orientations of structurally-related ligands can differ; A cautionary noteBinding interactions of antagonists with 5-hydroxytryptamine3A receptor models.The binding characteristics and orientation of a novel radioligand with distinct properties at 5-HT3A and 5-HT3AB receptorsTherapeutics of 5-HT3 receptor antagonists: current uses and future directions.5-HT(3) receptors.C≡N stretching vibration of 5-cyanotryptophan as an infrared probe of protein local environment: what determines its frequency?Loop B is a major structural component of the 5-HT3 receptor.Structural determinates for apolipoprotein E-derived peptide interaction with the alpha7 nicotinic acetylcholine receptorThe structural basis of function in Cys-loop receptors.Cysteine modification reveals which subunits form the ligand binding site in human heteromeric 5-HT3AB receptors.Prediction of 5-HT3 receptor agonist-binding residues using homology modeling.Mutagenesis and molecular modeling reveal the importance of the 5-HT3 receptor F-loop.Locating an antagonist in the 5-HT3 receptor binding site using modeling and radioligand binding.The role of tyrosine residues in the extracellular domain of the 5-hydroxytryptamine3 receptor.Arginine 222 in the pre-transmembrane domain 1 of 5-HT3A receptors links agonist binding to channel gating.Characterization of the ligand-binding site of the serotonin 5-HT3 receptor: the role of glutamate residues 97, 224, AND 235.Varenicline Interactions at the 5-HT3 Receptor Ligand Binding Site are Revealed by 5-HTBPExploring a potential palonosetron allosteric binding site in the 5-HT(3) receptor.Defining the roles of Asn-128, Glu-129 and Phe-130 in loop A of the 5-HT3 receptorUnbinding pathways of an agonist and an antagonist from the 5-HT3 receptorThe extracellular subunit interface of the 5-HT3 receptors: a computational alanine scanning mutagenesis study.Aromatic residues at position 55 of rat alpha7 nicotinic acetylcholine receptors are critical for maintaining rapid desensitization.
P2860
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P2860
The role of tryptophan residues in the 5-Hydroxytryptamine(3) receptor ligand binding domain.
description
2000 nî lūn-bûn
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2000年の論文
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2000年学术文章
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2000年学术文章
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2000年学术文章
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2000年学术文章
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2000年學術文章
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name
The role of tryptophan residue ...... eceptor ligand binding domain.
@en
type
label
The role of tryptophan residue ...... eceptor ligand binding domain.
@en
prefLabel
The role of tryptophan residue ...... eceptor ligand binding domain.
@en
P2860
P356
P1476
The role of tryptophan residue ...... eceptor ligand binding domain.
@en
P2093
P2860
P304
P356
10.1074/JBC.275.8.5620
P407
P577
2000-02-01T00:00:00Z