Profile of the GSK published protein kinase inhibitor set across ATP-dependent and-independent luciferases: implications for reporter-gene assays
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When Quality Beats Quantity: Decision Theory, Drug Discovery, and the Reproducibility CrisisThe ChEMBL bioactivity database: an updateComprehensive characterization of the Published Kinase Inhibitor SetIdentification and characterization of hundreds of potent and selective inhibitors of Trypanosoma brucei growth from a kinase-targeted library screening campaignApplications of chemogenomic library screening in drug discoverySeeding collaborations to advance kinase science with the GSK Published Kinase Inhibitor Set (PKIS)Identification of potent Yes1 kinase inhibitors using a library screening approach.Composition and applications of focus libraries to phenotypic assaysPAINS in the assay: chemical mechanisms of assay interference and promiscuous enzymatic inhibition observed during a sulfhydryl-scavenging HTS.Bioluminescence Methods for Assaying Kinases in Quantitative High-Throughput Screening (qHTS) Format Applied to Yes1 Tyrosine Kinase, Glucokinase, and PI5P4Kα Lipid Kinase.Non-stoichiometric inhibition in integrated lead finding - a literature review.Identification of "Preferred" Human Kinase Inhibitors for Sleeping Sickness Lead Discovery. Are Some Kinases Better than Others for Inhibitor Repurposing?Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci.Unprecedently Large-Scale Kinase Inhibitor Set Enabling the Accurate Prediction of Compound-Kinase Activities: A Way toward Selective Promiscuity by Design?Deciphering the true antiproliferative target of an MK2 activation inhibitor in glioblastoma.Signalome-wide assessment of host cell response to hepatitis C virus.Best of both worlds: on the complementarity of ligand-based and structure-based virtual screeningAn iterative compound screening contest method for identifying target protein inhibitors using the tyrosine-protein kinase Yes.Kinase inhibitor screening using artificial neural networks and engineered cardiac biowiresDifferential prioritization of therapies to subtypes of triple negative breast cancer using a systems medicine method.Functional annotation of chemical libraries across diverse biological processes.The ChEMBL database: a taster for medicinal chemists.Inhibition of CREB phosphorylation by conjugates of adenosine analogues and arginine-rich peptides, inhibitors of PKA catalytic subunit.Immuno-detection by sequencing enables large-scale high-dimensional phenotyping in cells.KInhibition: A Kinase Inhibitor Selection Portal
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P2860
Profile of the GSK published protein kinase inhibitor set across ATP-dependent and-independent luciferases: implications for reporter-gene assays
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2013 թվականին հրատարակված գիտական հոդված
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2013年の論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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Profile of the GSK published p ...... tions for reporter-gene assays
@ast
Profile of the GSK published p ...... tions for reporter-gene assays
@en
Profile of the GSK published p ...... tions for reporter-gene assays
@nl
type
label
Profile of the GSK published p ...... tions for reporter-gene assays
@ast
Profile of the GSK published p ...... tions for reporter-gene assays
@en
Profile of the GSK published p ...... tions for reporter-gene assays
@nl
prefLabel
Profile of the GSK published p ...... tions for reporter-gene assays
@ast
Profile of the GSK published p ...... tions for reporter-gene assays
@en
Profile of the GSK published p ...... tions for reporter-gene assays
@nl
P2093
P2860
P1433
P1476
Profile of the GSK published p ...... tions for reporter-gene assays
@en
P2093
Douglas S Auld
James Inglese
Patricia Dranchak
Rajarshi Guha
Ryan MacArthur
William J Zuercher
P2860
P304
P356
10.1371/JOURNAL.PONE.0057888
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P50
P577
2013-01-01T00:00:00Z