Raf-1 sets the threshold of Fas sensitivity by modulating Rok-alpha signaling
about
Nilotinib and MEK inhibitors induce synthetic lethality through paradoxical activation of RAF in drug-resistant chronic myeloid leukemiaRaf family kinases: old dogs have learned new tricksRASSF1A elicits apoptosis through an MST2 pathway directing proapoptotic transcription by the p73 tumor suppressor proteinPI3K-AKT-mTOR-signaling and beyond: the complex network in gastroenteropancreatic neuroendocrine neoplasmsRegulation of ROCK activity in cancerIntegrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapyRaf kinases in cancer-roles and therapeutic opportunitiesA genome-scale RNA-interference screen identifies RRAS signaling as a pathologic feature of Huntington's diseaseTNFα induces survival through the FLIP-L-dependent activation of the MAPK/ERK pathwayMAP kinase signalling pathways in cancerROCK2 is a major regulator of axonal degeneration, neuronal death and axonal regeneration in the CNS.CAML regulates Bim-dependent thymocyte death.ERK-MAPK signaling opposes rho-kinase to reduce cardiomyocyte apoptosis in heart ischemic preconditioning.The tumor suppressor DiRas3 forms a complex with H-Ras and C-RAF proteins and regulates localization, dimerization, and kinase activity of C-RAFBRAF inactivation drives aneuploidy by deregulating CRAFDeath Receptor-Induced Apoptosis Signalling Regulation by Ezrin Is Cell Type Dependent and Occurs in a DISC-Independent Manner in Colon Cancer Cells.Angiogenic sprouting requires the fine tuning of endothelial cell cohesion by the Raf-1/Rok-α complexIncreased BRAF heterodimerization is the common pathogenic mechanism for noonan syndrome-associated RAF1 mutantsRho kinase in the regulation of cell death and survival.TNFR1 promotes tumor necrosis factor-mediated mouse colon epithelial cell survival through RAF activation of NF-kappaB.Mechanistic principles of RAF kinase signaling.ROCKing Regeneration: Rho Kinase Inhibition as Molecular Target for Neurorestoration.It takes two to tango--signalling by dimeric Raf kinases.Rho-associated coiled-coil kinase (ROCK) signaling and disease."RAF" neighborhood: protein-protein interaction in the Raf/Mek/Erk pathway.Lipid rafts and raft-mediated supramolecular entities in the regulation of CD95 death receptor apoptotic signaling.RhoA/Rho kinase in spinal cord injury.The secret life of kinases: functions beyond catalysisc-Raf, but not B-Raf, is essential for development of K-Ras oncogene-driven non-small cell lung carcinomaEzrin is a negative regulator of death receptor-induced apoptosis.The roles of apoptotic pathways in the low recovery rate after cryopreservation of dissociated human embryonic stem cells.The long non-coding RNA PARROT is an upstream regulator of c-Myc and affects proliferation and translation.CRAF autophosphorylation of serine 621 is required to prevent its proteasome-mediated degradation.From autoinhibition to inhibition in trans: the Raf-1 regulatory domain inhibits Rok-alpha kinase activity.BAG1 promotes axonal outgrowth and regeneration in vivo via Raf-1 and reduction of ROCK activity.RhoA/Rho Kinase Mediates Neuronal Death Through Regulating cPLA2 Activation.Caspase-dependent cleavage disrupts the ERK cascade scaffolding function of KSR1.
P2860
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P2860
Raf-1 sets the threshold of Fas sensitivity by modulating Rok-alpha signaling
description
2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2005
@ast
im Dezember 2005 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2005/12/19)
@sk
vědecký článek publikovaný v roce 2005
@cs
wetenschappelijk artikel (gepubliceerd op 2005/12/19)
@nl
наукова стаття, опублікована в грудні 2005
@uk
مقالة علمية (نشرت في 19-12-2005)
@ar
name
Raf-1 sets the threshold of Fas sensitivity by modulating Rok-alpha signaling
@ast
Raf-1 sets the threshold of Fas sensitivity by modulating Rok-alpha signaling
@en
Raf-1 sets the threshold of Fas sensitivity by modulating Rok-alpha signaling
@nl
type
label
Raf-1 sets the threshold of Fas sensitivity by modulating Rok-alpha signaling
@ast
Raf-1 sets the threshold of Fas sensitivity by modulating Rok-alpha signaling
@en
Raf-1 sets the threshold of Fas sensitivity by modulating Rok-alpha signaling
@nl
prefLabel
Raf-1 sets the threshold of Fas sensitivity by modulating Rok-alpha signaling
@ast
Raf-1 sets the threshold of Fas sensitivity by modulating Rok-alpha signaling
@en
Raf-1 sets the threshold of Fas sensitivity by modulating Rok-alpha signaling
@nl
P2093
P2860
P921
P3181
P356
P1476
Raf-1 sets the threshold of Fas sensitivity by modulating Rok-alpha signaling
@en
P2093
Cristina Rubiolo
Daniela Piazzolla
Katrin Meissl
Lucia Kucerova
P2860
P304
P3181
P356
10.1083/JCB.200504137
P407
P577
2005-12-19T00:00:00Z