Plasticity and expanding complexity of the hepatic transcription factor network during liver development
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Identification of an endogenous ligand bound to a native orphan nuclear receptorDifferential binding and co-binding pattern of FOXA1 and FOXA3 and their relation to H3K4me3 in HepG2 cells revealed by ChIP-seqInvolvement of corepressor complex subunit GPS2 in transcriptional pathways governing human bile acid biosynthesisGenetic predictors of interindividual variability in hepatic CYP3A4 expressionRegulation of liver development: implications for liver biology across the lifespanEpistasis of transcriptomes reveals synergism between transcriptional activators Hnf1alpha and Hnf4alphaCrosstalk of HNF4α with extracellular and intracellular signaling pathways in the regulation of hepatic metabolism of drugs and lipidsRole of Hepatic-Specific Transcription Factors and Polycomb Repressive Complex 2 during Induction of Fibroblasts to Hepatic FateHepatocyte-ductal transdifferentiation is mediated by reciprocal repression of SOX9 and C/EBPα.DNA methylation profiling of the fibrinogen gene landscape in human cells and during mouse and zebrafish development.Hepatocyte nuclear factor 4alpha coordinates a transcription factor network regulating hepatic fatty acid metabolism.A systems approach to mapping transcriptional networks controlling surfactant homeostasis.Hepatocyte nuclear factor-4alpha induces transdifferentiation of hematopoietic cells into hepatocytesGenome-wide analyses of ChIP-Seq derived FOXA2 DNA occupancy in liver points to genetic networks underpinning multiple complex traits.Study of FoxA pioneer factor at silent genes reveals Rfx-repressed enhancer at Cdx2 and a potential indicator of esophageal adenocarcinoma developmentHNF1α inhibition triggers epithelial-mesenchymal transition in human liver cancer cell lines.Induction of highly functional hepatocytes from human umbilical cord mesenchymal stem cells by HNF4α transductionTransforming growth factor-β1 suppresses hepatitis B virus replication by the reduction of hepatocyte nuclear factor-4α expression.Beta-catenin signaling in hepatic development and progenitors: which way does the WNT blow?Induction of functional hepatocyte-like cells from mouse fibroblasts by defined factors.HNF-4α determines hepatic differentiation of human mesenchymal stem cells from bone marrow.Alterations in hepatic mRNA expression of phase II enzymes and xenobiotic transporters after targeted disruption of hepatocyte nuclear factor 4 alphaCooperativity and rapid evolution of cobound transcription factors in closely related mammalsPancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants.High-resolution mapping of transcriptional dynamics across tissue development reveals a stable mRNA-tRNA interfaceProteomic analysis of native hepatocyte nuclear factor-4α (HNF4α) isoforms, phosphorylation status, and interactive cofactors.Foxa2-dependent hepatic gene regulatory networks depend on physiological stateDifferentiation of human embryonic stem cells along a hepatic lineage.Deep resequencing of GWAS loci identifies rare variants in CARD9, IL23R and RNF186 that are associated with ulcerative colitis.Function of GATA factors in the adult mouse liver.Spontaneous development of hepatocellular carcinoma with cancer stem cell properties in PR-SET7-deficient livers.Comparison of the cytokine and chemokine dynamics of the early inflammatory response in models of burn injury and infectionMulti-species, multi-transcription factor binding highlights conserved control of tissue-specific biological pathways.TAF4, a subunit of transcription factor II D, directs promoter occupancy of nuclear receptor HNF4A during post-natal hepatocyte differentiation.HNF4A is essential for specification of hepatic progenitors from human pluripotent stem cells.Resetting the transcription factor network reverses terminal chronic hepatic failure.Human Enhancers Are Fragile and Prone to Deactivating MutationsAn HNF4α-miRNA inflammatory feedback circuit regulates hepatocellular oncogenesisOrchestrating liver development.Limited effects of bile acids and small heterodimer partner on hepatitis B virus biosynthesis in vivo.
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P248
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P2860
Plasticity and expanding complexity of the hepatic transcription factor network during liver development
description
2006 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2006
@ast
im August 2006 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
@en
vedecký článok (publikovaný 2006/08/15)
@sk
vědecký článek publikovaný v roce 2006
@cs
wetenschappelijk artikel (gepubliceerd op 2006/08/15)
@nl
наукова стаття, опублікована в серпні 2006
@uk
مقالة علمية (نشرت في 15-8-2006)
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name
Plasticity and expanding compl ...... twork during liver development
@ast
Plasticity and expanding compl ...... twork during liver development
@en
Plasticity and expanding compl ...... twork during liver development
@nl
type
label
Plasticity and expanding compl ...... twork during liver development
@ast
Plasticity and expanding compl ...... twork during liver development
@en
Plasticity and expanding compl ...... twork during liver development
@nl
prefLabel
Plasticity and expanding compl ...... twork during liver development
@ast
Plasticity and expanding compl ...... twork during liver development
@en
Plasticity and expanding compl ...... twork during liver development
@nl
P2093
P2860
P921
P3181
P356
P1433
P1476
Plasticity and expanding compl ...... twork during liver development
@en
P2093
Francois Tronche
Frank J. Gonzalez
Irene Kyrmizi
Nitsa Katrakili
Pantelis Hatzis
P2860
P304
P3181
P356
10.1101/GAD.390906
P577
2006-08-15T00:00:00Z