Congenic mapping and genotyping of the tetrahydrobiopterin-deficient hph-1 mouse
about
A requirement for Gch1 and tetrahydrobiopterin in embryonic developmentErythropoietin increases bioavailability of tetrahydrobiopterin and protects cerebral microvasculature against oxidative stress induced by eNOS uncouplingDihydrofolate reductase protects endothelial nitric oxide synthase from uncoupling in tetrahydrobiopterin deficiency.Differential effects of eNOS uncoupling on conduit and small arteries in GTP-cyclohydrolase I-deficient hph-1 mice.Regulation of β-adrenergic control of heart rate by GTP-cyclohydrolase 1 (GCH1) and tetrahydrobiopterin.Uncoupling of eNOS causes superoxide anion production and impairs NO signaling in the cerebral microvessels of hph-1 mice.Impaired behavioural pain responses in hph-1 mice with inherited deficiency in GTP cyclohydrolase 1 in models of inflammatory pain.Role of uncoupled endothelial nitric oxide synthase in abdominal aortic aneurysm formation: treatment with folic acidGCH1 haplotype determines vascular and plasma biopterin availability in coronary artery disease effects on vascular superoxide production and endothelial functionPolymorphisms of genes in nitric oxide-forming pathway associated with ischemic stroke in Chinese Han population.Combining Human and Rodent Genetics to Identify New Analgesics.GTP cyclohydrolase I expression, protein, and activity determine intracellular tetrahydrobiopterin levels, independent of GTP cyclohydrolase feedback regulatory protein expression.Tetrahydrobiopterin: a vascular redox target to improve endothelial function.
P2860
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P2860
Congenic mapping and genotyping of the tetrahydrobiopterin-deficient hph-1 mouse
description
2004 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2004
@ast
im Juli 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/07/01)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/07/01)
@nl
наукова стаття, опублікована в липні 2004
@uk
مقالة علمية (نشرت في يوليو 2004)
@ar
name
Congenic mapping and genotyping of the tetrahydrobiopterin-deficient hph-1 mouse
@ast
Congenic mapping and genotyping of the tetrahydrobiopterin-deficient hph-1 mouse
@en
Congenic mapping and genotyping of the tetrahydrobiopterin-deficient hph-1 mouse
@nl
type
label
Congenic mapping and genotyping of the tetrahydrobiopterin-deficient hph-1 mouse
@ast
Congenic mapping and genotyping of the tetrahydrobiopterin-deficient hph-1 mouse
@en
Congenic mapping and genotyping of the tetrahydrobiopterin-deficient hph-1 mouse
@nl
prefLabel
Congenic mapping and genotyping of the tetrahydrobiopterin-deficient hph-1 mouse
@ast
Congenic mapping and genotyping of the tetrahydrobiopterin-deficient hph-1 mouse
@en
Congenic mapping and genotyping of the tetrahydrobiopterin-deficient hph-1 mouse
@nl
P2093
P1476
Congenic mapping and genotyping of the tetrahydrobiopterin-deficient hph-1 mouse
@en
P2093
Jeffrey P Khoo
Jonathan Flint
Nicholas J Alp
Taija Nicoli
P304
P356
10.1016/J.YMGME.2004.04.006
P577
2004-07-01T00:00:00Z