Mammalian polyhomeotic homologues Phc2 and Phc1 act in synergy to mediate polycomb repression of Hox genes
about
Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A-ARF locusPHC3, a component of the hPRC-H complex, associates with E2F6 during G0 and is lost in osteosarcoma tumorsMAPKAP kinase MK2 maintains self-renewal capacity of haematopoietic stem cellsSeveral distinct polycomb complexes regulate and co-localize on the INK4a tumor suppressor locusUbiquitin-specific proteases 7 and 11 modulate Polycomb regulation of the INK4a tumour suppressorInteraction proteomics analysis of polycomb proteins defines distinct PRC1 complexes in mammalian cellsMultiple polymer architectures of human polyhomeotic homolog 3 sterile alpha motifMammalian polycomb-like Pcl2/Mtf2 is a novel regulatory component of PRC2 that can differentially modulate polycomb activity both at the Hox gene cluster and at Cdkn2a genesPolycomb complexes repress developmental regulators in murine embryonic stem cellsThe polycomb repressive complex 2 is a potential target of SUMO modifications.Changes in the distributions and dynamics of polycomb repressive complexes during embryonic stem cell differentiationTF-Cluster: a pipeline for identifying functionally coordinated transcription factors via network decomposition of the shared coexpression connectivity matrix (SCCM)ARF-induced downregulation of Mip130/LIN-9 protein levels mediates a positive feedback that leads to increased expression of p16Ink4a and p19Arf.NuRD-mediated deacetylation of H3K27 facilitates recruitment of Polycomb Repressive Complex 2 to direct gene repression.Dynamics of Polycomb and Trithorax activities during development.The B-MYB transcriptional network guides cell cycle progression and fate decisions to sustain self-renewal and the identity of pluripotent stem cells.Polycomb group complexes--many combinations, many functions.Recruitment of PRC1 function at the initiation of X inactivation independent of PRC2 and silencingPaternal heterochromatin formation in human embryos is H3K9/HP1 directed and primed by sperm-derived histone modifications.Lineage-specific regulation of epigenetic modifier genes in human liver and brainpRB family proteins are required for H3K27 trimethylation and Polycomb repression complexes binding to and silencing p16INK4alpha tumor suppressor gene.MK3 modulation affects BMI1-dependent and independent cell cycle check-points.A comprehensive ChIP-chip analysis of E2F1, E2F4, and E2F6 in normal and tumor cells reveals interchangeable roles of E2F family members.Multiple quantitative trait loci for cortical and trabecular bone regulation map to mid-distal mouse chromosome 4 that shares linkage homology to human chromosome 1p36RNA and protein actors in X-chromosome inactivation.Modular transcriptional repertoire and MicroRNA target analyses characterize genomic dysregulation in the thymus of Down syndrome infants.The Polycomb Group Protein Pcgf1 Is Dispensable in Zebrafish but Involved in Early Growth and Aging.Ash1l methylates Lys36 of histone H3 independently of transcriptional elongation to counteract polycomb silencingInterdependence of PRC1 and PRC2 for recruitment to Polycomb Response Elements.PCGF6-PRC1 suppresses premature differentiation of mouse embryonic stem cells by regulating germ cell-related genes.The time of timing: how Polycomb proteins regulate neurogenesis.Combinatorial assembly and function of chromatin regulatory complexes.Multiple layers of complexity in cis-regulatory regions of developmental genes.Polycomb group protein-mediated histone modifications during cell differentiation.Epigenetic balance of gene expression by Polycomb and COMPASS families.USP7 cooperates with SCML2 to regulate the activity of PRC1.Polycomb complexes act redundantly to repress genomic repeats and genes.Human polyhomeotic homolog 3 (PHC3) sterile alpha motif (SAM) linker allows open-ended polymerization of PHC3 SAM.Expression pattern and functional role of Phc2 during activation of helper T cells after antigenic stimulation.Samd7 is a cell type-specific PRC1 component essential for establishing retinal rod photoreceptor identity.
P2860
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P2860
Mammalian polyhomeotic homologues Phc2 and Phc1 act in synergy to mediate polycomb repression of Hox genes
description
2005 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2005
@ast
im August 2005 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2005/08/01)
@sk
vědecký článek publikovaný v roce 2005
@cs
wetenschappelijk artikel (gepubliceerd op 2005/08/01)
@nl
наукова стаття, опублікована в серпні 2005
@uk
مقالة علمية (نشرت في أغسطس 2005)
@ar
name
Mammalian polyhomeotic homolog ...... lycomb repression of Hox genes
@ast
Mammalian polyhomeotic homolog ...... lycomb repression of Hox genes
@en
Mammalian polyhomeotic homolog ...... lycomb repression of Hox genes
@nl
type
label
Mammalian polyhomeotic homolog ...... lycomb repression of Hox genes
@ast
Mammalian polyhomeotic homolog ...... lycomb repression of Hox genes
@en
Mammalian polyhomeotic homolog ...... lycomb repression of Hox genes
@nl
prefLabel
Mammalian polyhomeotic homolog ...... lycomb repression of Hox genes
@ast
Mammalian polyhomeotic homolog ...... lycomb repression of Hox genes
@en
Mammalian polyhomeotic homolog ...... lycomb repression of Hox genes
@nl
P2093
P2860
P921
P3181
P1476
Mammalian polyhomeotic homolog ...... lycomb repression of Hox genes
@en
P2093
Haruhiko Koseki
Jiyang O-Wang
Jun Shinga
Kyo-Ichi Isono
Makoto Yamaki
Yasuaki Murahashi
Yoko Mizutani-Koseki
Yoshihiro Takihara
Yu-Ichi Fujimura
Yuki Takada
P2860
P304
P3181
P356
10.1128/MCB.25.15.6694-6706.2005
P407
P577
2005-08-01T00:00:00Z