Rnf2 (Ring1b) deficiency causes gastrulation arrest and cell cycle inhibition - Wikidata - awgldk - TriplyDB

Rnf2 (Ring1b) deficiency causes gastrulation arrest and cell cycle inhibition

Rnf2 (Ring1b) deficiency causes gastrulation arrest and cell cycle inhibition

http://www.wikidata.org/entity/Q24554110

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CBX8, a polycomb group protein, is essential for MLL-AF9-induced leukemogenesis Role of histone H2A ubiquitination in Polycomb silencing The putative cancer stem cell marker USP22 is a subunit of the human SAGA complex required for activated transcription and cell-cycle progression Several distinct polycomb complexes regulate and co-localize on the INK4a tumor suppressor locus Structure and E3-ligase activity of the Ring-Ring complex of polycomb proteins Bmi1 and Ring1b Interaction proteomics analysis of polycomb proteins defines distinct PRC1 complexes in mammalian cells Epigenetic regulation of the INK4b-ARF-INK4a locus: in sickness and in health Epigenetic control of embryonic stem cell fate Embryonic stem cell and induced pluripotent stem cell: an epigenetic perspective Ex uno plures: molecular designs for embryonic pluripotency Bivalent histone modifications in early embryogenesis Normal formation of a vertebrate body plan and loss of tissue maintenance in the absence of ezh2.Coordinating cell proliferation and differentiation: Antagonism between cell cycle regulators and cell type-specific gene expression MAPKAP kinase 3pK phosphorylates and regulates chromatin association of the polycomb group protein Bmi1 The H3K36 demethylase Jhdm1b/Kdm2b regulates cell proliferation and senescence through p15(Ink4b)Mammalian polyhomeotic homologues Phc2 and Phc1 act in synergy to mediate polycomb repression of Hox genes The chromodomain helicase Chd4 is required for Polycomb-mediated inhibition of astroglial differentiation Ink4a and Arf differentially affect cell proliferation and neural stem cell self-renewal in Bmi1-deficient mice.Proteomics analysis of Ring1B/Rnf2 interactors identifies a novel complex with the Fbxl10/Jhdm1B histone demethylase and the Bcl6 interacting corepressor Impaired maturation of myeloid progenitors in mice lacking novel Polycomb group protein MBT-1 Polycomb complexes repress developmental regulators in murine embryonic stem cells Polycomb silencers control cell fate, development and cancer The polycomb repressive complex 2 is a potential target of SUMO modifications.Ring1B is crucial for the regulation of developmental control genes and PRC1 proteins but not X inactivation in embryonic cells.Changes in the distributions and dynamics of polycomb repressive complexes during embryonic stem cell differentiation Different polycomb group CBX family proteins associate with distinct regions of chromatin using nonhomologous protein sequences.Ubiquitin E3 ligase Ring1b/Rnf2 of polycomb repressive complex 1 contributes to stable maintenance of mouse embryonic stem cells The Polycomb protein and E3 ubiquitin ligase Ring1B harbors an IRES in its highly conserved 5' UTR Molecular architecture of polycomb repressive complexes Additional sex combs-like 1 belongs to the enhancer of trithorax and polycomb group and genetically interacts with Cbx2 in mice KAP1 represses differentiation-inducible genes in embryonic stem cells through cooperative binding with PRC1 and derepresses pluripotency-associated genes Polycomb group protein expression during differentiation of human embryonic stem cells into pancreatic lineage in vitro The Polycomb group protein RING1B is overexpressed in ductal breast carcinoma and is required to sustain FAK steady state levels in breast cancer epithelial cells.The histone H2A deubiquitinase Usp16 regulates embryonic stem cell gene expression and lineage commitment.Kdm2b maintains murine embryonic stem cell status by recruiting PRC1 complex to CpG islands of developmental genes.Distinct histone modifications in stem cell lines and tissue lineages from the early mouse embryo Gatekeeper of pluripotency: a common Oct4 transcriptional network operates in mouse eggs and embryonic stem cells ARF-induced downregulation of Mip130/LIN-9 protein levels mediates a positive feedback that leads to increased expression of p16Ink4a and p19Arf.RNF2 is recruited by WASH to ubiquitinate AMBRA1 leading to downregulation of autophagy Ring1B and Suv39h1 delineate distinct chromatin states at bivalent genes during early mouse lineage commitment

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Rnf2 (Ring1b) deficiency causes gastrulation arrest and cell cycle inhibition

http://www.wikidata.org/entity/Q24554110

description

2003 nî lūn-bûn

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2003 թուականի Մարտին հրատարակուած գիտական յօդուած

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2003 թվականի մարտին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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name

Rnf2 (Ring1b) deficiency causes gastrulation arrest and cell cycle inhibition

@ast

Rnf2 (Ring1b) deficiency causes gastrulation arrest and cell cycle inhibition

@en

Rnf2 (Ring1b) deficiency causes gastrulation arrest and cell cycle inhibition

@nl

type

label

Rnf2 (Ring1b) deficiency causes gastrulation arrest and cell cycle inhibition

@ast

Rnf2 (Ring1b) deficiency causes gastrulation arrest and cell cycle inhibition

@en

Rnf2 (Ring1b) deficiency causes gastrulation arrest and cell cycle inhibition

@nl

prefLabel

Rnf2 (Ring1b) deficiency causes gastrulation arrest and cell cycle inhibition

@ast

Rnf2 (Ring1b) deficiency causes gastrulation arrest and cell cycle inhibition

@en

Rnf2 (Ring1b) deficiency causes gastrulation arrest and cell cycle inhibition

@nl

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Proceedings of the National Academy of Sciences of the United States of America

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Rnf2 (Ring1b) deficiency causes gastrulation arrest and cell cycle inhibition

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Bernard A J Roelen

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Els Verhoeven

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Jacqueline Deschamps

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Jan Willem Voncken

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Maarten van Lohuizen

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Mieke Roefs

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Silvia Marino

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Stijn de Vries

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P2860

A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in G0 cells

The core of the polycomb repressive complex is compositionally and functionally conserved in flies and humans.

RING1 is associated with the polycomb group protein complex and acts as a transcriptional repressor

Characterization of interactions between the mammalian polycomb-group proteins Enx1/EZH2 and EED suggests the existence of different mammalian polycomb-group protein complexes.

Interaction of mouse polycomb-group (Pc-G) proteins Enx1 and Enx2 with Eed: indication for separate Pc-G complexes.

Selective interactions between vertebrate polycomb homologs and the SUV39H1 histone lysine methyltransferase suggest that histone H3-K9 methylation contributes to chromosomal targeting of Polycomb group proteins.

The E2F6 transcription factor is a component of the mammalian Bmi1-containing polycomb complex

Identification and characterization of interactions between the vertebrate polycomb-group protein BMI1 and human homologs of polyhomeotic

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

A generic protein purification method for protein complex characterization and proteome exploration

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