Inhibition of prostasin-induced ENaC activities by PN-1 and regulation of PN-1 expression by TGF-beta1 and aldosterone
about
The role of transforming growth factor β1 in the regulation of blood pressureRegulation and dysregulation of epithelial Na+ channelsPlasmin in nephrotic urine activates the epithelial sodium channelMembrane-anchored serine proteases in vertebrate cell and developmental biologyRegulation of sodium transport by ENaC in the kidneyInterleukin-6 stimulates epithelial sodium channels in mouse cortical collecting duct cellsProteolytic activation of the epithelial sodium channel and therapeutic application of a serine protease inhibitor for the treatment of salt-sensitive hypertension.Intracellular ubiquitylation of the epithelial Na+ channel controls extracellular proteolytic channel activation via conformational change.The channel-activating protease CAP1/Prss8 is required for placental labyrinth maturation.Urinary prostasin excretion is associated with adiposity in nonhypertensive African-American adolescents.Cathepsin B is secreted apically from Xenopus 2F3 cells and cleaves the epithelial sodium channel (ENaC) to increase its activity.Prostasin expression is regulated by airway surface liquid volume and is increased in cystic fibrosis.Protease nexin-1, tPA, and PAI-1 are upregulated in cryoglobulinemic membranoproliferative glomerulonephritis.Transforming growth factor-β1 and diabetic nephropathyThe cutting edge: membrane-anchored serine protease activities in the pericellular microenvironment.Membrane-anchored serine proteases in health and disease.ENaC at the cutting edge: regulation of epithelial sodium channels by proteases.Transforming growth factor beta1 and aldosterone.The function and regulation of acid-sensing ion channels (ASICs) and the epithelial Na(+) channel (ENaC): IUPHAR Review 19.Increased expression of protease nexin-1 in fibroblasts during idiopathic pulmonary fibrosis regulates thrombin activity and fibronectin expression.Cleavage in the {gamma}-subunit of the epithelial sodium channel (ENaC) plays an important role in the proteolytic activation of near-silent channels.Serpine2 deficiency results in lung lymphocyte accumulation and bronchus-associated lymphoid tissue formation.Epithelial Na+ Channel Regulation by Extracellular and Intracellular Factors.Reduced ENaC protein abundance contributes to the lower blood pressure observed in pendrin-null mice.Albuminuria is associated with an increased prostasin in urine while aldosterone has no direct effect on urine and kidney tissue abundance of prostasin.Loss of HAI-2 in mice with decreased prostasin activity leads to an early-onset intestinal failure resembling congenital tufting enteropathy.
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P2860
Inhibition of prostasin-induced ENaC activities by PN-1 and regulation of PN-1 expression by TGF-beta1 and aldosterone
description
2006 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2006
@ast
im Oktober 2006 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2006/10/01)
@sk
vědecký článek publikovaný v roce 2006
@cs
wetenschappelijk artikel (gepubliceerd op 2006/10/01)
@nl
наукова стаття, опублікована в жовтні 2006
@uk
مقالة علمية (نشرت في أكتوبر 2006)
@ar
name
Inhibition of prostasin-induce ...... n by TGF-beta1 and aldosterone
@ast
Inhibition of prostasin-induce ...... n by TGF-beta1 and aldosterone
@en
Inhibition of prostasin-induce ...... n by TGF-beta1 and aldosterone
@nl
type
label
Inhibition of prostasin-induce ...... n by TGF-beta1 and aldosterone
@ast
Inhibition of prostasin-induce ...... n by TGF-beta1 and aldosterone
@en
Inhibition of prostasin-induce ...... n by TGF-beta1 and aldosterone
@nl
prefLabel
Inhibition of prostasin-induce ...... n by TGF-beta1 and aldosterone
@ast
Inhibition of prostasin-induce ...... n by TGF-beta1 and aldosterone
@en
Inhibition of prostasin-induce ...... n by TGF-beta1 and aldosterone
@nl
P2093
P921
P356
P1433
P1476
Inhibition of prostasin-induce ...... n by TGF-beta1 and aldosterone
@en
P2093
A. Maekawa
D. G. Tuyen
H. Nonoguchi
K. Kitamura
N. Shiraishi
T. Miyoshi
P2888
P304
P356
10.1038/SJ.KI.5001787
P407
P577
2006-10-01T00:00:00Z
P5875
P6179
1042889661