Dose-dependent interaction of Tbx1 and Crkl and locally aberrant RA signaling in a model of del22q11 syndrome
about
MAP'ing CNS development and cognition: an ERKsome processThe adaptor protein Crk in immune responseOf mice and men: molecular genetics of congenital heart diseaseThe neural crest in cardiac congenital anomaliesTbx1 regulates the BMP-Smad1 pathway in a transcription independent manner.Modeling a model: Mouse genetics, 22q11.2 Deletion Syndrome, and disorders of cortical circuit developmentPrdm1 functions in the mesoderm of the second heart field, where it interacts genetically with Tbx1, during outflow tract morphogenesis in the mouse embryoFgf8 expression in the Tbx1 domain causes skeletal abnormalities and modifies the aortic arch but not the outflow tract phenotype of Tbx1 mutantsPartial rescue of the Tbx1 mutant heart phenotype by Fgf8: genetic evidence of impaired tissue response to Fgf8Mesodermal expression of Tbx1 is necessary and sufficient for pharyngeal arch and cardiac outflow tract developmentTbx1 controls cardiac neural crest cell migration during arch artery development by regulating Gbx2 expression in the pharyngeal ectodermThe mammalian doublesex homolog DMRT1 is a transcriptional gatekeeper that controls the mitosis versus meiosis decision in male germ cellsThe retinaldehyde reductase DHRS3 is essential for preventing the formation of excess retinoic acid during embryonic developmentEvolutionary and developmental origins of the cardiac neural crest: building a divided outflow tractA pre-metazoan origin of the CRK gene family and co-opted signaling networkIdentification of putative retinoic acid target genes downstream of mesenchymal Tbx1 during inner ear developmentSchizophrenia and 22q11.2 deletion syndrome.Chordin is a modifier of tbx1 for the craniofacial malformations of 22q11 deletion syndrome phenotypes in mouse.Tbx1 and Brn4 regulate retinoic acid metabolic genes during cochlear morphogenesis.Retinoic acid signaling organizes endodermal organ specification along the entire antero-posterior axisBeta-catenin deficiency causes DiGeorge syndrome-like phenotypes through regulation of Tbx1.Tbx1 modulates endodermal and mesodermal differentiation from mouse induced pluripotent stem cells.Decreased levels of embryonic retinoic acid synthesis accelerate recovery from arterial growth delay in a mouse model of DiGeorge syndromeNovel TBX1 loss-of-function mutation causes isolated conotruncal heart defects in Chinese patients without 22q11.2 deletion.Endothelial neuropilin disruption in mice causes DiGeorge syndrome-like malformations via mechanisms distinct to those caused by loss of Tbx1Phenotypic impact of genomic structural variation: insights from and for human disease.Genotype-phenotype correlation in 22q11.2 deletion syndrome.Functional zebrafish studies based on human genotyping point to netrin-1 as a link between aberrant cardiovascular development and thyroid dysgenesisA mouse splice-site mutant and individuals with atypical chromosome 22q11.2 deletions demonstrate the crucial role for crkl in craniofacial and pharyngeal development.Molecular characterization of deletion breakpoints in adults with 22q11 deletion syndromeExpression in the human brain of retinoic acid induced 1, a protein associated with neurobehavioural disorders.A defect in early myogenesis causes Otitis media in two mouse models of 22q11.2 Deletion Syndrome.Genotype and cardiovascular phenotype correlations with TBX1 in 1,022 velo-cardio-facial/DiGeorge/22q11.2 deletion syndrome patients.Crkl deficiency disrupts Fgf8 signaling in a mouse model of 22q11 deletion syndromes.RIPPLY3 is a retinoic acid-inducible repressor required for setting the borders of the pre-placodal ectodermGenetic pathways to mammalian heart development: Recent progress from manipulation of the mouse genome.Identification of a Tbx1/Tbx2/Tbx3 genetic pathway governing pharyngeal and arterial pole morphogenesis22q11 Gene dosage establishes an adaptive range for sonic hedgehog and retinoic acid signaling during early development.Hard to swallow: Developmental biological insights into pediatric dysphagia.Model systems for the study of heart development and disease. Cardiac neural crest and conotruncal malformations
P2860
Q24621710-67449F94-0E63-4F14-8499-FB8B1447DBC1Q26849320-162B096F-81E7-4D93-A580-C948A1EAF60EQ26995476-DF1BFB02-A88F-448D-99A9-EB85F414CF39Q27024385-5B5FC1BB-F9B9-4FC0-A813-46C9A5E373CCQ27863405-B9E979FC-A3DB-48F6-A40A-746884C835F2Q28081179-2142406C-F7E4-4AD7-B2E9-1AAD212F4073Q28509491-538A87EE-41D3-4E47-9978-03B8B07F493EQ28513912-E5CF5D76-CC04-4502-A7C2-903D094EA187Q28585923-E0E0A8B7-FA08-43E4-B2A0-CCF45BE557EFQ28587491-B1A1C7F4-BBD9-448C-9152-7E68F839A851Q28588434-41B04595-CDE4-4ABA-B309-13E6491A9584Q28588842-6960B3F9-B07E-4E19-B3A8-A3E85F009B52Q28593890-09D08CF6-A4CE-4ECB-B6AA-9BEA990DB6BAQ28652450-6750376A-5A4C-4442-9057-6C5EF34B21ABQ30008856-F2A28088-C726-4D2B-BE6B-DBDEDDD3FABAQ30505432-8871EB35-41AE-4E3B-A36F-F102E7AD8330Q31155236-E6058CD9-F37C-4F5D-9FC6-D5AE97692585Q33413046-430FF5AB-51B8-412A-ACEB-CE8E8CA9C0D9Q33455008-2B63B336-9B9D-4B99-9DE1-FAE47B854239Q33466026-9974D722-4F1F-43C8-AFFB-08ABD567D283Q33714238-6C653FC6-1D84-4AFB-8875-767AD701BF06Q33788869-86C0C2A5-8AF7-4B29-B3FC-54642CC489BCQ33829670-F35F68C3-73A7-460A-B683-83AC4FFB7650Q33905027-84223B74-6388-46FA-BE2D-2470F4222018Q34187192-50DCD992-5249-4826-89ED-EA7AACB86A59Q34323221-712AE88A-F6C0-43B3-A4DC-F667FC2AA664Q34514307-BBD7A26B-4110-43EC-897B-C21D5FF88A11Q34745253-F927C1CC-70F2-45C3-A543-FA3906EB712CQ34800084-8A7A43F7-9A6D-4B39-84BF-6969B3979EB7Q35115385-F8CD97AA-5FB2-4418-B680-A5A28FA05A6FQ35123153-FF8A08B8-446D-473E-BFB7-BBADDECBDBA1Q35163449-3F562CFF-2D56-499F-A03D-A38A67BD5601Q35388414-2A03B3D1-A91E-4433-9191-2988DFCA12C2Q35606917-DF63B213-2E93-425A-83F1-54C63BB33C2AQ35768103-6E345193-BE7B-4A37-A23A-F87CB5CDA5CCQ35916112-7FB6501D-6B53-4BE2-88CD-BCEA3E405116Q36379778-613D6E34-55C0-4606-BCE6-36B1AC923B53Q36477668-CB691ACE-49AB-453D-AF0C-13E2C49188E6Q36494895-B273AFEB-9AB6-4B31-9143-316A68082810Q36708506-F06F3286-1D94-46DA-A7FC-3EB5B6EA101A
P2860
Dose-dependent interaction of Tbx1 and Crkl and locally aberrant RA signaling in a model of del22q11 syndrome
description
2006 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2006
@ast
im Januar 2006 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2006/01/01)
@sk
vědecký článek publikovaný v roce 2006
@cs
wetenschappelijk artikel (gepubliceerd op 2006/01/01)
@nl
наукова стаття, опублікована в січні 2006
@uk
مقالة علمية (نشرت عام 2006)
@ar
name
Dose-dependent interaction of ...... n a model of del22q11 syndrome
@ast
Dose-dependent interaction of ...... n a model of del22q11 syndrome
@en
Dose-dependent interaction of ...... n a model of del22q11 syndrome
@nl
type
label
Dose-dependent interaction of ...... n a model of del22q11 syndrome
@ast
Dose-dependent interaction of ...... n a model of del22q11 syndrome
@en
Dose-dependent interaction of ...... n a model of del22q11 syndrome
@nl
prefLabel
Dose-dependent interaction of ...... n a model of del22q11 syndrome
@ast
Dose-dependent interaction of ...... n a model of del22q11 syndrome
@en
Dose-dependent interaction of ...... n a model of del22q11 syndrome
@nl
P3181
P1433
P1476
Dose-dependent interaction of ...... n a model of del22q11 syndrome
@en
P2093
Akira Imamoto
Deborah L Guris
P3181
P356
10.1016/J.DEVCEL.2005.12.002
P407
P577
2006-01-01T00:00:00Z