Mesodermal expression of Tbx1 is necessary and sufficient for pharyngeal arch and cardiac outflow tract development
about
The clinical spectrum of homozygous HOXA1 mutationsEvolution and development of the vertebrate neckCiona as a Simple Chordate Model for Heart Development and RegenerationTBX1 Represses Vegfr2 Gene Expression and Enhances the Cardiac Fate of VEGFR2+ CellsTbx1 regulates the BMP-Smad1 pathway in a transcription independent manner.Prdm1 functions in the mesoderm of the second heart field, where it interacts genetically with Tbx1, during outflow tract morphogenesis in the mouse embryoTbx1 regulates population, proliferation and cell fate determination of otic epithelial cellsTbx1 regulates proliferation and differentiation of multipotent heart progenitorsPartial rescue of the Tbx1 mutant heart phenotype by Fgf8: genetic evidence of impaired tissue response to Fgf8Great vessel development requires biallelic expression of Chd7 and Tbx1 in pharyngeal ectoderm in miceTbx1 controls cardiac neural crest cell migration during arch artery development by regulating Gbx2 expression in the pharyngeal ectodermA Tbx1-Six1/Eya1-Fgf8 genetic pathway controls mammalian cardiovascular and craniofacial morphogenesisEarly thyroid development requires a Tbx1-Fgf8 pathwayIn vivo genetic ablation of the periotic mesoderm affects cell proliferation survival and differentiation in the cochlea.Mesodermal Tbx1 is required for patterning the proximal mandible in miceTbx1 regulates progenitor cell proliferation in the dental epithelium by modulating Pitx2 activation of p21Early chordate origins of the vertebrate second heart fieldChick Lrrn2, a novel downstream effector of Hoxb1 and Shh, functions in the selective targeting of rhombomere 4 motor neuronsTbx1 controls the morphogenesis of pharyngeal pouch epithelia through mesodermal Wnt11r and Fgf8a.Tbx1 and Brn4 regulate retinoic acid metabolic genes during cochlear morphogenesis.Engineered chromosome-based genetic mapping establishes a 3.7 Mb critical genomic region for Down syndrome-associated heart defects in miceBeta-catenin deficiency causes DiGeorge syndrome-like phenotypes through regulation of Tbx1.AcvR1-mediated BMP signaling in second heart field is required for arterial pole development: implications for myocardial differentiation and regional identity.Tbx1 modulates endodermal and mesodermal differentiation from mouse induced pluripotent stem cells.Tbx1 is required autonomously for cell survival and fate in the pharyngeal core mesoderm to form the muscles of mastication.Endothelial neuropilin disruption in mice causes DiGeorge syndrome-like malformations via mechanisms distinct to those caused by loss of Tbx1p53 Suppression partially rescues the mutant phenotype in mouse models of DiGeorge syndrome.Jun is required in Isl1-expressing progenitor cells for cardiovascular developmentDiGeorge syndrome gene tbx1 functions through wnt11r to regulate heart looping and differentiationNK4 antagonizes Tbx1/10 to promote cardiac versus pharyngeal muscle fate in the ascidian second heart fieldInactivation of Bmp4 from the Tbx1 expression domain causes abnormal pharyngeal arch artery and cardiac outflow tract remodeling.Mesodermal Nkx2.5 is necessary and sufficient for early second heart field developmentGenetic pathways to mammalian heart development: Recent progress from manipulation of the mouse genome.Tbx1 is a negative modulator of Mef2c.Origin, Specification, and Plasticity of the Great Vessels of the Heart.How insights from cardiovascular developmental biology have impacted the care of infants and children with congenital heart disease.Partitioning the heart: mechanisms of cardiac septation and valve developmentDisruption of Smad4 in neural crest cells leads to mid-gestation death with pharyngeal arch, craniofacial and cardiac defectsModel systems for the study of heart development and disease. Cardiac neural crest and conotruncal malformationsTbx1 is required for second heart field proliferation in zebrafish
P2860
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P2860
Mesodermal expression of Tbx1 is necessary and sufficient for pharyngeal arch and cardiac outflow tract development
description
2006 nî lūn-bûn
@nan
2006 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Mesodermal expression of Tbx1 ...... diac outflow tract development
@ast
Mesodermal expression of Tbx1 ...... diac outflow tract development
@en
Mesodermal expression of Tbx1 ...... diac outflow tract development
@nl
type
label
Mesodermal expression of Tbx1 ...... diac outflow tract development
@ast
Mesodermal expression of Tbx1 ...... diac outflow tract development
@en
Mesodermal expression of Tbx1 ...... diac outflow tract development
@nl
prefLabel
Mesodermal expression of Tbx1 ...... diac outflow tract development
@ast
Mesodermal expression of Tbx1 ...... diac outflow tract development
@en
Mesodermal expression of Tbx1 ...... diac outflow tract development
@nl
P2860
P3181
P356
P1433
P1476
Mesodermal expression of Tbx1 ...... diac outflow tract development
@en
P2093
Antonio Baldini
Tuong Huynh
P2860
P304
P3181
P356
10.1242/DEV.02539
P407
P50
P577
2006-08-16T00:00:00Z