Restoration of cone vision in a mouse model of achromatopsia
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Gene therapy rescues cone function in congenital achromatopsia.AAV-mediated gene therapy in mouse models of recessive retinal degenerationA comprehensive review of retinal gene therapyCanine CNGA3 Gene Mutations Provide Novel Insights into Human Achromatopsia-Associated Channelopathies and TreatmentGene Augmentation Therapy Restores Retinal Function and Visual Behavior in a Sheep Model of CNGA3 AchromatopsiaBiology and therapy of inherited retinal degenerative disease: insights from mouse modelsMutations in the unfolded protein response regulator ATF6 cause the cone dysfunction disorder achromatopsiaAAV-mediated cone rescue in a naturally occurring mouse model of CNGA3-achromatopsiaRestoration of cone vision in the CNGA3-/- mouse model of congenital complete lack of cone photoreceptor functionThe human rhodopsin kinase promoter in an AAV5 vector confers rod- and cone-specific expression in the primate retina.Intraocular route of AAV2 vector administration defines humoral immune response and therapeutic potentialOcular delivery of compacted DNA-nanoparticles does not elicit toxicity in the mouse retinaNon-invasive stem cell therapy in a rat model for retinal degeneration and vascular pathology.Gene therapy with a promoter targeting both rods and cones rescues retinal degeneration caused by AIPL1 mutationsEvaluation of a behavioral method for objective vision testing and identification of achromatopsia in dogs.Functional and behavioral restoration of vision by gene therapy in the guanylate cyclase-1 (GC1) knockout mouse.Adaptive optics retinal imaging--clinical opportunities and challengesSelf-complementary AAV5 vector facilitates quicker transgene expression in photoreceptor and retinal pigment epithelial cells of normal mouse.Distinct and conserved prominin-1/CD133-positive retinal cell populations identified across speciesIn vivo imaging of human cone photoreceptor inner segments.Mechanistic basis for the failure of cone transducin to translocate: why cones are never blinded by lightA Quantitative and Qualitative Exploration of Photoaversion in Achromatopsia.Mutation discovered in a feline model of human congenital retinal blinding disease.γ-Secretase inhibition of murine choroidal neovascularization is associated with reduction of superoxide and proinflammatory cytokines.A prospective longitudinal study of retinal structure and function in achromatopsia.Dark-adaptation functions in molecularly confirmed achromatopsia and the implications for assessment in retinal therapy trials.Self-complementary AAV-mediated gene therapy restores cone function and prevents cone degeneration in two models of Rpe65 deficiency.Genotype-dependent variability in residual cone structure in achromatopsia: toward developing metrics for assessing cone healthVector platforms for gene therapy of inherited retinopathies.Genomic deletion of CNGB3 is identical by descent in multiple canine breeds and causes achromatopsia.AAV-mediated photoreceptor transduction of the pig cone-enriched retina.Long-term and age-dependent restoration of visual function in a mouse model of CNGB3-associated achromatopsia following gene therapyNatural history of cone disease in the murine model of Leber congenital amaurosis due to CEP290 mutation: determining the timing and expectation of therapy.Gene therapy for ocular diseasesRepublished review: Gene therapy for ocular diseases.Photoreceptor structure and function in patients with congenital achromatopsia.C1q enhances cone photoreceptor survival in a mouse model of autosomal recessive retinitis pigmentosa.Gene therapy rescues photoreceptor blindness in dogs and paves the way for treating human X-linked retinitis pigmentosa.X-linked juvenile retinoschisis: clinical diagnosis, genetic analysis, and molecular mechanisms.Mutation in the platelet-derived growth factor receptor alpha inhibits adeno-associated virus type 5 transduction.
P2860
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P2860
Restoration of cone vision in a mouse model of achromatopsia
description
2007 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2007
@ast
im Juni 2007 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2007/06/01)
@sk
vědecký článek publikovaný v roce 2007
@cs
wetenschappelijk artikel (gepubliceerd op 2007/06/01)
@nl
наукова стаття, опублікована в червні 2007
@uk
مقالة علمية (نشرت في يونيو 2007)
@ar
name
Restoration of cone vision in a mouse model of achromatopsia
@ast
Restoration of cone vision in a mouse model of achromatopsia
@en
Restoration of cone vision in a mouse model of achromatopsia
@nl
type
label
Restoration of cone vision in a mouse model of achromatopsia
@ast
Restoration of cone vision in a mouse model of achromatopsia
@en
Restoration of cone vision in a mouse model of achromatopsia
@nl
prefLabel
Restoration of cone vision in a mouse model of achromatopsia
@ast
Restoration of cone vision in a mouse model of achromatopsia
@en
Restoration of cone vision in a mouse model of achromatopsia
@nl
P2093
P2860
P3181
P356
P1433
P1476
Restoration of cone vision in a mouse model of achromatopsia
@en
P2093
Adrian M. Timmers
Drew Everhart
Ji-Jing Pang
John J. Alexander
Norman L. Hawes
Qiuhong Li
Robert B. Barlow
Seok H. Min
William W. Hauswirth
P2860
P2888
P304
P3181
P356
10.1038/NM1596
P407
P577
2007-06-01T00:00:00Z