Arf4 is required for Mammalian development but dispensable for ciliary assembly
about
Structure of Rab11-FIP3-Rabin8 reveals simultaneous binding of FIP3 and Rabin8 effectors to Rab11The Arf and Rab11 effector FIP3 acts synergistically with ASAP1 to direct Rabin8 in ciliary receptor targetingLoss of Arf4 causes severe degeneration of the exocrine pancreas but not cystic kidney disease or retinal degenerationTrafficking to the primary cilium membrane.A Presenilin-2-ARF4 trafficking axis modulates Notch signaling during epidermal differentiationCilia and DiseasesRegulation of polycystin-1 ciliary trafficking by motifs at its C-terminus and polycystin-2 but not by cleavage at the GPS siteTubby family proteins are adapters for ciliary trafficking of integral membrane proteinsRab GTPases in cilium formation and function.The Arf GEF GBF1 and Arf4 synergize with the sensory receptor cargo, rhodopsin, to regulate ciliary membrane trafficking.BLOC-1 is required for selective membrane protein trafficking from endosomes to primary cilia.
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Q27701769-83FB4CC3-7F2C-43F5-84A7-D2D03ABC29F7Q28508183-E7C96C68-23A5-436D-9E8F-B9E6FAB78F24Q30352739-F73A3C52-AF7F-46B0-B513-E0FA0F9BF79DQ30353488-B14CD493-E569-41B1-8956-B8E1FA391684Q30780422-207EB5FA-DCEB-46DC-82D6-1F4B06049C76Q35571167-3AE8C112-FCF3-4B1F-98B2-D0EA0ABA73F0Q36462325-A39D9016-29F2-4651-B237-A583F587B6D0Q38718216-4EAE10F8-D4FC-4B97-A020-CEA8C8EC9DD7Q42517436-8092FB00-4A21-4C1F-B2D8-6A4F35EFC76AQ47660256-5F76DD5B-392C-4AF6-91E1-2E2EF64C8004Q47826855-F7CFA099-5346-43A9-BBEB-F850A0FC5A10
P2860
Arf4 is required for Mammalian development but dispensable for ciliary assembly
description
2014 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2014
@ast
im Februar 2014 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2014/02/01)
@sk
vědecký článek publikovaný v roce 2014
@cs
wetenschappelijk artikel (gepubliceerd op 2014/02/01)
@nl
наукова стаття, опублікована в лютому 2014
@uk
مقالة علمية (نشرت في فبراير 2014)
@ar
name
Arf4 is required for Mammalian development but dispensable for ciliary assembly
@ast
Arf4 is required for Mammalian development but dispensable for ciliary assembly
@en
Arf4 is required for Mammalian development but dispensable for ciliary assembly
@nl
type
label
Arf4 is required for Mammalian development but dispensable for ciliary assembly
@ast
Arf4 is required for Mammalian development but dispensable for ciliary assembly
@en
Arf4 is required for Mammalian development but dispensable for ciliary assembly
@nl
prefLabel
Arf4 is required for Mammalian development but dispensable for ciliary assembly
@ast
Arf4 is required for Mammalian development but dispensable for ciliary assembly
@en
Arf4 is required for Mammalian development but dispensable for ciliary assembly
@nl
P2093
P2860
P921
P3181
P1433
P1476
Arf4 is required for Mammalian development but dispensable for ciliary assembly
@en
P2093
Jaime A Rivera-Perez
John A Follit
Jovenal T San Agustin
Julie A Jonassen
Kimberly D Tremblay
Tingting Huang
P2860
P304
P3181
P356
10.1371/JOURNAL.PGEN.1004170
P577
2014-02-20T00:00:00Z