Role of TC21/R-Ras2 in enhanced migration of neurofibromin-deficient Schwann cells
about
Molecular mechanisms promoting the pathogenesis of Schwann cell neoplasmsNf1 RasGAP inhibition of LIMK2 mediates a new cross-talk between Ras and Rho pathwaysIn vivo regulation of TGF-β by R-Ras2 revealed through loss of the RasGAP protein NF1.Reduced growth of Drosophila neurofibromatosis 1 mutants reflects a non-cell-autonomous requirement for GTPase-Activating Protein activity in larval neurons.Classic Ras Proteins Promote Proliferation and Survival via Distinct Phosphoproteome Alterations in Neurofibromin-Null Malignant Peripheral Nerve Sheath Tumor Cells.Schweinfurthin A selectively inhibits proliferation and Rho signaling in glioma and neurofibromatosis type 1 tumor cells in a NF1-GRD-dependent manner.Genome-wide functional screen identifies a compendium of genes affecting sensitivity to tamoxifen.Hyperactive RAS/PI3-K/MAPK Signaling Cascade in Migration and Adhesion of Nf1 Haploinsufficient Mesenchymal Stem/Progenitor Cells.Tumor suppressor mutations and growth factor signaling in the pathogenesis of NF1-associated peripheral nerve sheath tumors. I. The role of tumor suppressor mutations.The Ras-like protein R-Ras2/TC21 is important for proper mammary gland development.Partial Blindness to Submicron Topography in NF1 Haploinsufficient Cultured Fibroblasts Indicates a New Function of Neurofibromin in Regulation of Mechanosensoric.Neurofibromin regulates somatic growth through the hypothalamic-pituitary axisHow does the Schwann cell lineage form tumors in NF1?Structural and spatial determinants regulating TC21 activation by RasGRF family nucleotide exchange factorsRas-driven transcriptome analysis identifies aurora kinase A as a potential malignant peripheral nerve sheath tumor therapeutic target.Oligodendrocyte progenitor cell numbers and migration are regulated by the zebrafish orthologs of the NF1 tumor suppressor genePalmitoylation regulates vesicular trafficking of R-Ras to membrane ruffles and effects on ruffling and cell spreading.
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P2860
Role of TC21/R-Ras2 in enhanced migration of neurofibromin-deficient Schwann cells
description
2004 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հունվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2004
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im Januar 2004 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 2004/01/15)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/01/15)
@nl
наукова стаття, опублікована в січні 2004
@uk
مقالة علمية (نشرت في 15-1-2004)
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name
Role of TC21/R-Ras2 in enhanced migration of neurofibromin-deficient Schwann cells
@ast
Role of TC21/R-Ras2 in enhanced migration of neurofibromin-deficient Schwann cells
@en
Role of TC21/R-Ras2 in enhanced migration of neurofibromin-deficient Schwann cells
@nl
type
label
Role of TC21/R-Ras2 in enhanced migration of neurofibromin-deficient Schwann cells
@ast
Role of TC21/R-Ras2 in enhanced migration of neurofibromin-deficient Schwann cells
@en
Role of TC21/R-Ras2 in enhanced migration of neurofibromin-deficient Schwann cells
@nl
prefLabel
Role of TC21/R-Ras2 in enhanced migration of neurofibromin-deficient Schwann cells
@ast
Role of TC21/R-Ras2 in enhanced migration of neurofibromin-deficient Schwann cells
@en
Role of TC21/R-Ras2 in enhanced migration of neurofibromin-deficient Schwann cells
@nl
P2093
P2860
P921
P356
P1433
P1476
Role of TC21/R-Ras2 in enhanced migration of neurofibromin-deficient Schwann cells
@en
P2093
Adrienne D. Cox
Fatima Rangwala
John Kamholz
Nancy Ratner
Patricia C. Fulkerson
Yuan Huang
P2860
P2888
P304
P356
10.1038/SJ.ONC.1207075
P407
P577
2004-01-15T00:00:00Z
P5875
P6179
1045829746