The mouse slalom mutant demonstrates a role for Jagged1 in neuroepithelial patterning in the organ of Corti
about
Focusing on the genetics of hearing: you ain't heard nothin' yet.The Notch ligand JAG1 is required for sensory progenitor development in the mammalian inner earSegregating neural and mechanosensory fates in the developing ear: patterning, signaling, and transcriptional control.Family Wide Molecular Adaptations to Underground Life in African Mole-Rats Revealed by Phylogenomic Analysis.A murine model of neurofibromatosis type 2 that accurately phenocopies human schwannoma formationCanonical Notch signaling plays an instructive role in auditory supporting cell development.The candidate splicing factor Sfswap regulates growth and patterning of inner ear sensory organsSox2 is required for sensory organ development in the mammalian inner earThe canonical Notch signaling pathway: unfolding the activation mechanism.Requirement for Jagged1-Notch2 signaling in patterning the bones of the mouse and human middle ear.Transcript profiling of functionally related groups of genes during conditional differentiation of a mammalian cochlear hair cell line.Hesr1 and Hesr2 may act as early effectors of Notch signaling in the developing cochleaDelayed fusion and altered gene expression contribute to semicircular canal defects in Chd7 deficient miceNumb is not a critical regulator of Notch-mediated cell fate decisions in the developing chick inner ear.Basic helix-loop-helix gene Hes6 delineates the sensory hair cell lineage in the inner ear.Building the world's best hearing aid; regulation of cell fate in the cochleaThe mouse: genetics meets behaviour.Molecular and comparative genetics of mental retardation.The Notch ligand Jagged1 is required for inner ear sensory development.In vivo Notch reactivation in differentiating cochlear hair cells induces Sox2 and Prox1 expression but does not disrupt hair cell maturation.Overactivation of Notch1 signaling induces ectopic hair cells in the mouse inner ear in an age-dependent manner.Development of hair cells in inner ear is associated with expression and promoter methylation of Notch-1 in postnatal mice.Genetic background modifies inner ear and eye phenotypes of jag1 heterozygous mice.Regulation of cell fate in the sensory epithelia of the inner ear.A novel non-canonical Notch signaling regulates expression of synaptic vesicle proteins in excitatory neurons.Development and regeneration of hair cells.Familial deafness, congenital heart defects, and posterior embryotoxon caused by cysteine substitution in the first epidermal-growth-factor-like domain of jagged 1.Specification of cell fate in the mammalian cochleaHair cell progenitors: identification and regulatory genes.Canonical and non-canonical Notch ligands.Patterning and cell fate in the inner ear: a case for Notch in the chicken embryo.The plasma membrane calcium pump in health and disease.Therapeutic modulation of Notch signalling--are we there yet?Alternative splicing of inner-ear-expressed genes.Hes5 expression in the postnatal and adult mouse inner ear and the drug-damaged cochlea.Jagged1-mediated Notch signaling regulates mammalian inner ear development independent of lateral inhibition.Identification of Domains for Efficient Notch Signaling Activity in Immobilized Notch Ligand Proteins.A hearing and vestibular phenotyping pipeline to identify mouse mutants with hearing impairment.Screening for novel ENU-induced rhythm, entrainment and activity mutants.Notch1 and Jagged1 expression by the developing pulmonary vasculature.
P2860
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P2860
The mouse slalom mutant demonstrates a role for Jagged1 in neuroepithelial patterning in the organ of Corti
description
2001 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մարտին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2001
@ast
im März 2001 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2001/03/01)
@sk
vědecký článek publikovaný v roce 2001
@cs
wetenschappelijk artikel (gepubliceerd op 2001/03/01)
@nl
наукова стаття, опублікована в березні 2001
@uk
مقالة علمية (نشرت في مارس 2001)
@ar
name
The mouse slalom mutant demons ...... tterning in the organ of Corti
@ast
The mouse slalom mutant demons ...... tterning in the organ of Corti
@en
The mouse slalom mutant demons ...... tterning in the organ of Corti
@nl
type
label
The mouse slalom mutant demons ...... tterning in the organ of Corti
@ast
The mouse slalom mutant demons ...... tterning in the organ of Corti
@en
The mouse slalom mutant demons ...... tterning in the organ of Corti
@nl
prefLabel
The mouse slalom mutant demons ...... tterning in the organ of Corti
@ast
The mouse slalom mutant demons ...... tterning in the organ of Corti
@en
The mouse slalom mutant demons ...... tterning in the organ of Corti
@nl
P2093
P3181
P356
P1476
The mouse slalom mutant demons ...... tterning in the organ of Corti
@en
P2093
A. E. Kiernan
A. J. Hunter
K. P. Steel
R. E. Hardisty
S. D. Brown
P304
P3181
P356
10.1093/HMG/10.5.507
P577
2001-03-01T00:00:00Z