Hesr1 and Hesr2 may act as early effectors of Notch signaling in the developing cochlea - Wikidata - awgldk - TriplyDB

Hesr1 and Hesr2 may act as early effectors of Notch signaling in the developing cochlea

Hesr1 and Hesr2 may act as early effectors of Notch signaling in the developing cochlea

http://www.wikidata.org/entity/Q30481816

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Cyclic stretch stimulates vascular smooth muscle cell alignment by redox-dependent activation of Notch3 Early development of the vertebrate inner ear Molecular mechanisms of inner ear development Segregating neural and mechanosensory fates in the developing ear: patterning, signaling, and transcriptional control.Where hearing starts: the development of the mammalian cochlea Hey2 regulation by FGF provides a Notch-independent mechanism for maintaining pillar cell fate in the organ of Corti Pax2 contributes to inner ear patterning and optic nerve trajectory Role of chromatin remodeling gene Cecr2 in neurulation and inner ear development Fgf20 is required for sensory epithelial specification in the developing cochlea Co-regulation of the Notch and Wnt signaling pathways promotes supporting cell proliferation and hair cell regeneration in mouse utricles.Wnt activation followed by Notch inhibition promotes mitotic hair cell regeneration in the postnatal mouse cochlea.A central to peripheral progression of cell cycle exit and hair cell differentiation in the developing mouse cristae.Transcriptomic Analysis of Mouse Cochlear Supporting Cell Maturation Reveals Large-Scale Changes in Notch Responsiveness Prior to the Onset of Hearing.The Role of Atonal Factors in Mechanosensory Cell Specification and Function Sensory hair cell regeneration in the zebrafish lateral line.Regulated reprogramming in the regeneration of sensory receptor cells.Changes in the regulation of the Notch signaling pathway are temporally correlated with regenerative failure in the mouse cochlea The postnatal accumulation of junctional E-cadherin is inversely correlated with the capacity for supporting cells to convert directly into sensory hair cells in mammalian balance organs Inner ear supporting cells: rethinking the silent majority.Lgr5-positive supporting cells generate new hair cells in the postnatal cochlea.The challenge of hair cell regeneration.Notch signaling limits supporting cell plasticity in the hair cell-damaged early postnatal murine cochlea In vivo visualization of Notch1 proteolysis reveals the heterogeneity of Notch1 signaling activity in the mouse cochlea.Inhibition of Notch activity promotes nonmitotic regeneration of hair cells in the adult mouse utricles Hair cell fate decisions in cochlear development and regeneration Notch regulation of progenitor cell behavior in quiescent and regenerating auditory epithelium of mature birds.Notch signaling specifies prosensory domains via lateral induction in the developing mammalian inner ear The Notch effector Hey1 associates with myogenic target genes to repress myogenesis.Building the world's best hearing aid; regulation of cell fate in the cochlea Delta/notch-like EGF-related receptor (DNER) is expressed in hair cells and neurons in the developing and adult mouse inner ear Regulation of cell fate and patterning in the developing mammalian cochlea.The prosensory function of Sox2 in the chicken inner ear relies on the direct regulation of Atoh1.Hey1 and Hey2 control the spatial and temporal pattern of mammalian auditory hair cell differentiation downstream of Hedgehog signaling In vivo Notch reactivation in differentiating cochlear hair cells induces Sox2 and Prox1 expression but does not disrupt hair cell maturation.Overactivation of Notch1 signaling induces ectopic hair cells in the mouse inner ear in an age-dependent manner.A dual function for canonical Wnt/β-catenin signaling in the developing mammalian cochlea.Notch prosensory effects in the Mammalian cochlea are partially mediated by Fgf20.Selection of cell fate in the organ of Corti involves the integration of Hes/Hey signaling at the Atoh1 promoter.Conditional deletion of Atoh1 reveals distinct critical periods for survival and function of hair cells in the organ of Corti.Notch signaling during cell fate determination in the inner ear.

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Hesr1 and Hesr2 may act as early effectors of Notch signaling in the developing cochlea

http://www.wikidata.org/entity/Q30481816

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2008年の論文

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2008年论文

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Hesr1 and Hesr2 may act as early effectors of Notch signaling in the developing cochlea

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Hesr1 and Hesr2 may act as early effectors of Notch signaling in the developing cochlea

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Hesr1 and Hesr2 may act as early effectors of Notch signaling in the developing cochlea

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Hesr1 and Hesr2 may act as early effectors of Notch signaling in the developing cochlea

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Hesr1 and Hesr2 may act as early effectors of Notch signaling in the developing cochlea

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Hesr1 and Hesr2 may act as early effectors of Notch signaling in the developing cochlea

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J.YDBIO.2008.01.006

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Developmental Biology

P1476

Hesr1 and Hesr2 may act as early effectors of Notch signaling in the developing cochlea

@en

P2093

Byron H Hartman

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Catherine A Ray

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Hiroki Kokubo

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Olivia Bermingham-McDonogh

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Thomas A Reh

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Toshinori Hayashi

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P2860

Notch signalling pathway mediates hair cell development in mammalian cochlea

MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors

A human protein with sequence similarity to Drosophila mastermind coordinates the nuclear form of notch and a CSL protein to build a transcriptional activator complex on target promoters

The Notch ligand JAG1 is required for sensory progenitor development in the mammalian inner ear

A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE

Hey genes: a novel subfamily of hairy- and Enhancer of split related genes specifically expressed during mouse embryogenesis

Expression of Delta1 and Serrate1 (Jagged1) in the mouse inner ear

Structural requirements for assembly of the CSL.intracellular Notch1.Mastermind-like 1 transcriptional activation complex

HES and HERP families: multiple effectors of the Notch signaling pathway

Notch signaling: control of cell communication and cell fate

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87-99

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10.1016/J.YDBIO.2008.01.006

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1

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316

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5561552

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18291358

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2362132

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