FSGS-associated alpha-actinin-4 (K256E) impairs cytoskeletal dynamics in podocytes
about
Familial focal segmental glomerulosclerosis (FSGS)-linked α-actinin 4 (ACTN4) protein mutants lose ability to activate transcription by nuclear hormone receptorsPlanar cell polarity pathway regulates actin rearrangement, cell shape, motility, and nephrin distribution in podocytesTRPC6 in glomerular health and disease: what we know and what we believePodocytesCrystal Structure of the Actin-Binding Domain of α-Actinin-4 Lys255Glu Mutant Implicated in Focal Segmental Glomerulosclerosisα-Actinin-4/FSGS1 is required for Arp2/3-dependent actin assembly at the adherens junctionShiga toxin promotes podocyte injury in experimental hemolytic uremic syndrome via activation of the alternative pathway of complementGenetic causes of proteinuria and nephrotic syndrome: impact on podocyte pathobiology.Alpha-actinin-4 and CLP36 protein deficiencies contribute to podocyte defects in multiple human glomerulopathies.Focal segmental glomerulosclerosis: molecular genetics and targeted therapiesProteinuria: is it all in the foot?Progress in pathogenesis of proteinuria.Diabetes and Kidney Disease: Role of Oxidative Stress.Nephropathy and elevated BP in mice with podocyte-specific NADPH oxidase 5 expression.Pathogenesis and therapy of focal segmental glomerulosclerosis: an update.Educational paper: the podocytopathies.Relevance of the ACTN4 gene in African-Americans with non-diabetic end-stage renal disease.The role of alpha-actinin-4 in human kidney disease.Tandem phosphorylation within an intrinsically disordered region regulates ACTN4 function.Overexpression of Myo1e in mouse podocytes enhances cellular endocytosis, migration, and adhesion.Disease modeling in genetic kidney diseases: mice.Three-layered proteomic characterization of a novel ACTN4 mutation unravels its pathogenic potential in FSGS.Podocyte Injury Associated with Mutant α-Actinin-4Glomerular epithelial cell injury associated with mutant alpha-actinin-4.Endoplasmic reticulum stress, the unfolded protein response and autophagy in kidney diseases.Hereditary Podocytopathies in Adults: The Next Generation.The Evolving Complexity of the Podocyte Cytoskeleton.Non-muscle myosins and the podocyte.SGLT2 inhibitor dapagliflozin limits podocyte damage in proteinuric nondiabetic nephropathyRecent Progress in the Pathogenesis of Nephrotic Proteinuria
P2860
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P2860
FSGS-associated alpha-actinin-4 (K256E) impairs cytoskeletal dynamics in podocytes
description
2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2006
@ast
im September 2006 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2006/09/01)
@sk
vědecký článek publikovaný v roce 2006
@cs
wetenschappelijk artikel (gepubliceerd op 2006/09/01)
@nl
наукова стаття, опублікована у вересні 2006
@uk
مقالة علمية (نشرت في سبتمبر 2006)
@ar
name
FSGS-associated alpha-actinin-4 (K256E) impairs cytoskeletal dynamics in podocytes
@ast
FSGS-associated alpha-actinin-4 (K256E) impairs cytoskeletal dynamics in podocytes
@en
FSGS-associated alpha-actinin-4 (K256E) impairs cytoskeletal dynamics in podocytes
@nl
type
label
FSGS-associated alpha-actinin-4 (K256E) impairs cytoskeletal dynamics in podocytes
@ast
FSGS-associated alpha-actinin-4 (K256E) impairs cytoskeletal dynamics in podocytes
@en
FSGS-associated alpha-actinin-4 (K256E) impairs cytoskeletal dynamics in podocytes
@nl
prefLabel
FSGS-associated alpha-actinin-4 (K256E) impairs cytoskeletal dynamics in podocytes
@ast
FSGS-associated alpha-actinin-4 (K256E) impairs cytoskeletal dynamics in podocytes
@en
FSGS-associated alpha-actinin-4 (K256E) impairs cytoskeletal dynamics in podocytes
@nl
P2093
P356
P1433
P1476
FSGS-associated alpha-actinin-4 (K256E) impairs cytoskeletal dynamics in podocytes
@en
P2093
C. R. J. Kennedy
J.-L. R. Michaud
K. M. Chaisson
R. J. Parks
P2888
P304
P356
10.1038/SJ.KI.5001665
P407
P577
2006-09-01T00:00:00Z
P5875
P6179
1019101242