Dynamic and multi-pharmacophore modeling for designing polo-box domain inhibitors

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The hunt for antimitotic agents: an overview of structure-based design strategies.

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Dynamic and multi-pharmacophore modeling for designing polo-box domain inhibitors

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2014 թուականին հրատարակուած գիտական յօդուած

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2014 թվականին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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Dynamic and multi-pharmacophore modeling for designing polo-box domain inhibitors

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Dynamic and multi-pharmacophore modeling for designing polo-box domain inhibitors

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Dynamic and multi-pharmacophore modeling for designing polo-box domain inhibitors

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Dynamic and multi-pharmacophore modeling for designing polo-box domain inhibitors

@ast

Dynamic and multi-pharmacophore modeling for designing polo-box domain inhibitors

@en

Dynamic and multi-pharmacophore modeling for designing polo-box domain inhibitors

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Dynamic and multi-pharmacophore modeling for designing polo-box domain inhibitors

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Dynamic and multi-pharmacophore modeling for designing polo-box domain inhibitors

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Dynamic and multi-pharmacophore modeling for designing polo-box domain inhibitors

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P1476

Dynamic and multi-pharmacophore modeling for designing polo-box domain inhibitors

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P2093

Keun Woo Lee

http://www.w3.org/2001/XMLSchema#string

Qianfan Yang

http://www.w3.org/2001/XMLSchema#string

Silvia Senese

http://www.w3.org/2001/XMLSchema#string

P2860

Plk1 self-organization and priming phosphorylation of HsCYK-4 at the spindle midzone regulate the onset of division in human cells

Phosphorylation- and polo-box-dependent binding of Plk1 to Bub1 is required for the kinetochore localization of Plk1

Myosin phosphatase-targeting subunit 1 regulates mitosis by antagonizing polo-like kinase 1

The crystal structure of the human polo-like kinase-1 polo box domain and its phospho-peptide complex

Inhibitors targeting mitosis: tales of how great drugs against a promising target were brought down by a flawed rationale

The Sak polo-box comprises a structural domain sufficient for mitotic subcellular localization

The molecular basis for phosphodependent substrate targeting and regulation of Plks by the Polo-box domain

Molecular and structural basis of polo-like kinase 1 substrate recognition: Implications in centrosomal localization

Structural and functional analyses of minimal phosphopeptides targeting the polo-box domain of polo-like kinase 1

From Crystal Packing to Molecular Recognition: Prediction and Discovery of a Binding Site on the Surface of Polo-Like Kinase 1

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e101405

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scholarly article

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10.1371/JOURNAL.PONE.0101405

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English

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Jorge Z. Torres

Sugunadevi Sakkiah

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2014-01-01T00:00:00Z

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264053605

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25036740

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4103762

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Dynamic and multi-pharmacophore modeling for designing polo-box domain inhibitors

about

P2860

P2860

Dynamic and multi-pharmacophore modeling for designing polo-box domain inhibitors

description

name

type

label

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P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P5875

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P5875

P698

P932