about
C5L2 is a functional receptor for acylation-stimulating proteinThe role of the N-terminal domain of the complement fragment receptor C5L2 in ligand bindingTLR activation enhances C5a-induced pro-inflammatory responses by negatively modulating the second C5a receptor, C5L2Beta-arrestin- but not G protein-mediated signaling by the "decoy" receptor CXCR7Function, structure and therapeutic potential of complement C5a receptorsComplement activation in the context of stem cells and tissue repairAntimicrobial peptides and complement in neonatal hypoxia-ischemia induced brain damageProtein-based therapies for acute lung injury: targeting neutrophil extracellular trapsC5a mutants are potent antagonists of the C5a receptor (CD88) and of C5L2: position 69 is the locus that determines agonism or antagonismComplement System Part II: Role in ImmunityLigand specificity of the anaphylatoxin C5L2 receptor and its regulation on myeloid and epithelial cell linesA Comparative Study of Impedance versus Optical Label-Free Systems Relative to Labelled Assays in a Predominantly Gi Coupled GPCR (C5aR) Signalling.The Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptorsThe C5a receptor (C5aR) C5L2 is a modulator of C5aR-mediated signal transduction.The Controversial C5a Receptor C5aR2: Its Role in Health and Disease.A novel role for the fifth component of complement (C5) in cardiac physiology.Absence of signaling into CD4⁺ cells via C3aR and C5aR enables autoinductive TGF-β1 signaling and induction of Foxp3⁺ regulatory T cells.Role of C3a receptors, C5a receptors, and complement protein C6 deficiency in collagen antibody-induced arthritis in mice.The complement systemRecombinant acylation stimulating protein administration to C3-/- mice increases insulin resistance via adipocyte inflammatory mechanisms.Complement System Part I - Molecular Mechanisms of Activation and Regulation.C5a receptor-deficient dendritic cells promote induction of Treg and Th17 cellsRelationship of C5L2 receptor to skeletal muscle substrate utilization.Deficiency of C5L2 increases macrophage infiltration and alters adipose tissue function in mice.C5a receptor deficiency alters energy utilization and fat storage.A pro-inflammatory role of C5L2 in C5a-primed neutrophils for ANCA-induced activation.The role of the anaphylatoxins in health and disease.Complement activation product C5a is a selective suppressor of TLR4-induced, but not TLR3-induced, production of IL-27(p28) from macrophages.Discovery of functionally selective C5aR2 ligands: novel modulators of C5a signalling.Disruption of the complement anaphylatoxin receptor C5L2 exacerbates inflammation in allergic contact dermatitisRole of C3, C5 and anaphylatoxin receptors in acute lung injury and in sepsisCharacterization of Pharmacologic and Pharmacokinetic Properties of CCX168, a Potent and Selective Orally Administered Complement 5a Receptor Inhibitor, Based on Preclinical Evaluation and Randomized Phase 1 Clinical Study.Novel C5a regulators in inflammatory disease.Differential Contributions of the Complement Anaphylotoxin Receptors C5aR1 and C5aR2 to the Early Innate Immune Response against Staphylococcus aureus Infection.Complement 5a receptor-mediated neutrophil dysfunction is associated with a poor outcome in sepsis.C5a receptor-dependent cell activation by physiological concentrations of desarginated C5a: insights from a novel label-free cellular assay.New approaches to the study of sepsisFcgammaRIII is protective against Pseudomonas aeruginosa pneumoniaThe role of complement, C5a and its receptors in sepsis and multiorgan dysfunction syndrome.Experimental design of complement component 5a-induced acute lung injury (C5a-ALI): a role of CC-chemokine receptor type 5 during immune activation by anaphylatoxin.
P2860
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P2860
description
2003 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2003
@ast
im August 2003 veröffentlicher wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2003/08/12)
@sk
vědecký článek publikovaný v roce 2003
@cs
wetenschappelijk artikel (gepubliceerd op 2003/08/12)
@nl
наукова стаття, опублікована в серпні 2003
@uk
مقالة علمية (نشرت في 12-8-2003)
@ar
name
C5L2, a nonsignaling C5A binding protein
@ast
C5L2, a nonsignaling C5A binding protein
@en
C5L2, a nonsignaling C5A binding protein
@nl
type
label
C5L2, a nonsignaling C5A binding protein
@ast
C5L2, a nonsignaling C5A binding protein
@en
C5L2, a nonsignaling C5A binding protein
@nl
prefLabel
C5L2, a nonsignaling C5A binding protein
@ast
C5L2, a nonsignaling C5A binding protein
@en
C5L2, a nonsignaling C5A binding protein
@nl
P2093
P3181
P356
P1433
P1476
C5L2, a nonsignaling C5A binding protein
@en
P2093
Alison Humbles
Craig Gerard
Dubhfeasa Slattery
Hye-Ryun Choe
James E Krause
Michele Bennett Kinrade
Norma P Gerard
Olivier Morteau
Robbin M Brodbeck
Shoji Okinaga
P304
P3181
P356
10.1021/BI034489V
P407
P577
2003-08-01T00:00:00Z