Crystal structure of nerve growth factor in complex with the ligand-binding domain of the TrkA receptor
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Structural interactions of fibroblast growth factor receptor with its ligandsbeta -Amyloid peptide-induced apoptosis regulated by a novel protein containing a g protein activation moduleIL-17s adopt a cystine knot fold: structure and activity of a novel cytokine, IL-17F, and implications for receptor bindingStructural insights into the Slit-Robo complexCell signaling by receptor tyrosine kinases3D domain swapping: as domains continue to swapStructural basis of receptor sharing by interleukin 17 cytokinesNeurotrophins: roles in neuronal development and functionNeurotrophin-regulated signalling pathwaysStructural basis for stem cell factor–KIT signaling and activation of class III receptor tyrosine kinasesA mechanistic basis for converting a receptor tyrosine kinase agonist to an antagonistMolecular and Structural Insight into proNGF Engagement of p75NTR and SortilinCytokine Spatzle binds to the Drosophila immunoreceptor Toll with a neurotrophin-like specificity and couples receptor activationGeneration of a high-fidelity antibody against nerve growth factor using library scanning mutagenesis and validation with structures of the initial and optimized Fab-antigen complexesIsolation of recombinant BMP receptor IA ectodomain and its 2:1 complex with BMP-2Conformational plasticity of proNGFAgrin binds to the N-terminal region of Lrp4 protein and stimulates association between Lrp4 and the first immunoglobulin-like domain in muscle-specific kinase (MuSK)Crystal structure of the agrin-responsive immunoglobulin-like domains 1 and 2 of the receptor tyrosine kinase MuSKSodium depletion increases sympathetic neurite outgrowth and expression of a novel TMEM35 gene-derived protein (TUF1) in the rat adrenal zona glomerulosaSingle cycle structure-based humanization of an anti-nerve growth factor therapeutic antibodyTaking pain out of NGF: a "painless" NGF mutant, linked to hereditary sensory autonomic neuropathy type V, with full neurotrophic activitySmall-molecule inhibitors of protein-protein interactions: progressing towards the dreamOverview of protein structural and functional folds.Predicting a double mutant in the twilight zone of low homology modeling for the skeletal muscle voltage-gated sodium channel subunit beta-1 (Nav1.4 β1).Low molecular weight, non-peptidic agonists of TrkA receptor with NGF-mimetic activityA close look at axonal transport: Cargos slow down when crossing stationary organelles.Molecular dynamics simulations of the NGF-TrkA domain 5 complex and comparison with biological data.Cyclic-AMP response element-based signaling assays for characterization of Trk family tyrosine kinases modulators.Mechanisms of activation of receptor tyrosine kinases: monomers or dimers.TrkA immunoglobulin-like ligand binding domains inhibit spontaneous activation of the receptorProtein-protein interactions in receptor activation and intracellular signalling.A novel NGF mutation clarifies the molecular mechanism and extends the phenotypic spectrum of the HSAN5 neuropathy.Nerve growth factor signals via preexisting TrkA receptor oligomersSignaling receptome: a genomic and evolutionary perspective of plasma membrane receptors involved in signal transduction.Directed evolution of brain-derived neurotrophic factor for improved folding and expression in Saccharomyces cerevisiae.Functional map and domain structure of MET, the product of the c-met protooncogene and receptor for hepatocyte growth factor/scatter factorBiochemical and biophysical investigation of the brain-derived neurotrophic factor mimetic 7,8-dihydroxyflavone in the binding and activation of the TrkB receptor.Intranasal "painless" human Nerve Growth Factor [corrected] slows amyloid neurodegeneration and prevents memory deficits in App X PS1 miceSmall-molecule modulation of neurotrophin receptors: a strategy for the treatment of neurological disease.Structural basis of hepatocyte growth factor/scatter factor and MET signalling.
P2860
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P2860
Crystal structure of nerve growth factor in complex with the ligand-binding domain of the TrkA receptor
description
1999 nî lūn-bûn
@nan
1999 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
name
Crystal structure of nerve gro ...... ng domain of the TrkA receptor
@ast
Crystal structure of nerve gro ...... ng domain of the TrkA receptor
@en
Crystal structure of nerve gro ...... ng domain of the TrkA receptor
@en-gb
Crystal structure of nerve gro ...... ng domain of the TrkA receptor
@nl
type
label
Crystal structure of nerve gro ...... ng domain of the TrkA receptor
@ast
Crystal structure of nerve gro ...... ng domain of the TrkA receptor
@en
Crystal structure of nerve gro ...... ng domain of the TrkA receptor
@en-gb
Crystal structure of nerve gro ...... ng domain of the TrkA receptor
@nl
prefLabel
Crystal structure of nerve gro ...... ng domain of the TrkA receptor
@ast
Crystal structure of nerve gro ...... ng domain of the TrkA receptor
@en
Crystal structure of nerve gro ...... ng domain of the TrkA receptor
@en-gb
Crystal structure of nerve gro ...... ng domain of the TrkA receptor
@nl
P2093
P356
P1433
P1476
Crystal structure of nerve gro ...... ng domain of the TrkA receptor
@en
P2093
P2888
P304
P356
10.1038/43705
P407
P577
1999-09-01T00:00:00Z
P6179
1009144394