MuSK IgG4 autoantibodies cause myasthenia gravis by inhibiting binding between MuSK and Lrp4. - Wikidata - awgldk - TriplyDB

MuSK IgG4 autoantibodies cause myasthenia gravis by inhibiting binding between MuSK and Lrp4.

MuSK IgG4 autoantibodies cause myasthenia gravis by inhibiting binding between MuSK and Lrp4.

http://www.wikidata.org/entity/Q37409458

about

Pathogenesis of myasthenia gravis: update on disease types, models, and mechanisms Clinical features, pathogenesis, and treatment of myasthenia gravis: a supplement to the Guidelines of the German Neurological Society Mapping autoantigen epitopes: molecular insights into autoantibody-associated disorders of the nervous system Effects of the ß2-adrenoceptor agonist, albuterol, in a mouse model of anti-MuSK myasthenia gravis IgG-specific cell-based assay detects potentially pathogenic MuSK-Abs in seronegative MG LRP4 is critical for neuromuscular junction maintenance Altered active zones, vesicle pools, nerve terminal conductivity, and morphology during experimental MuSK myasthenia gravis Mitochondrial-dependent Autoimmunity in Membranous Nephropathy of IgG4-related Disease.Chronic inflammatory demyelinating polyradiculoneuropathy: from pathology to phenotype.Collagen Q and anti-MuSK autoantibody competitively suppress agrin/LRP4/MuSK signaling.Response to treatment of myasthenia gravis according to clinical subtype Forced expression of muscle specific kinase slows postsynaptic acetylcholine receptor loss in a mouse model of MuSK myasthenia gravis Myasthenia gravis: a clinical-immunological update.Specific contactin N-glycans are implicated in neurofascin binding and autoimmune targeting in peripheral neuropathies.IgG4-associated cholangitis: a comprehensive review.IgG4-related disease and its pathogenesis-cross-talk between innate and acquired immunity.Mechanisms controlling neuromuscular junction stability.Neuromuscular synaptogenesis: coordinating partners with multiple functions.Neuronal involvement in muscular atrophy.Maintenance plasma exchange treatment for muscle specific kinase antibody positive myasthenia gravis patients.Overcoming challenges in the diagnosis and treatment of myasthenia gravis.Myasthenia gravis: recent advances in immunopathology and therapy.Musk Kinase Activity is Modulated By A Serine Phosphorylation Site in The Kinase Loop Synaptic Homeostasis and Its Immunological Disturbance in Neuromuscular Junction Disorders.Autoantibodies in chronic inflammatory neuropathies: diagnostic and therapeutic implications.Molecular cloning and partial characterization of a low-density lipoprotein receptor-related protein 13 (Lrp13) involved in vitellogenin uptake in the cutthroat trout (Oncorhynchus clarki).Inhibitory axons are targeted in hippocampal cell culture by anti-Caspr2 autoantibodies associated with limbic encephalitis.Autoimmune Thyroiditis and Myasthenia Gravis.Diverging roles for Lrp4 and Wnt signaling in neuromuscular synapse development during evolution.Extensive glycosylation of ACPA-IgG variable domains modulates binding to citrullinated antigens in rheumatoid arthritis.Compromised fidelity of B-cell tolerance checkpoints in AChR and MuSK myasthenia gravis.The mouse passive-transfer model of MuSK myasthenia gravis: disrupted MuSK signaling causes synapse failure.Diagnostic utility of cortactin antibodies in myasthenia gravis.Myasthenia gravis with antibodies to MuSK: an update.IgG4-mediated autoimmune diseases: a niche of antibody-mediated disorders.Agrin-LRP4-MuSK signaling as a therapeutic target for myasthenia gravis and other neuromuscular disorders.Mechanisms of Caspr2 antibodies in autoimmune encephalitis and neuromyotonia.Preserving neuromuscular synapses in ALS by stimulating MuSK with a therapeutic agonist antibody.Circulating microRNAs as potential biomarkers in myasthenia gravis patients.Fundamental Molecules and Mechanisms for Forming and Maintaining Neuromuscular Synapses.

P2860

Q26740634-89564667-D413-489C-96F2-028A081C825C Q26765172-B2145CFD-C4DE-430C-BEA1-40FA5248BBDF Q28075974-C1DAEBD6-A60F-4694-9D88-FDF93299A493 Q28539518-2175CFDC-243A-4266-B77F-52976367F901 Q33765716-4EF343C4-3560-4681-983B-475BAF936FE6 Q34345625-C68147D1-D601-4D25-8F0C-A36932C42533 Q34599589-E196D830-DDA7-474A-B3E4-F445FC470A26 Q35799662-38884CC1-72AE-4276-B0EC-2A0C87EEC6A1 Q36005389-2C4A8280-C6F9-4512-B67F-EB056EA865FE Q36044172-BA900D04-FF1E-41AA-BE2F-584EC5D1ACFF Q36195346-2EB28E86-CD7A-4010-87A4-09DA7EFBE28C Q36597860-52E52C6E-21E7-4E45-97A6-F59399A955B0 Q36783864-B503237E-E13C-42C6-A3DF-A7CF52C2E77F Q37635865-0CC01477-B3A6-4008-8DAF-FD567B099FFE Q38222686-8B086A65-4A1C-4AED-A774-5B0F49DC2FBA Q38229557-45923AE9-7052-4B05-8B8F-C60582B88170 Q38264058-90D335B3-1B45-457A-87C7-50D2E18D6B2C Q38286009-A823D79C-D80D-4710-8C8C-83BAA4E72AB1 Q38300566-2D487665-3045-4172-8240-916135BBB79E Q38306801-E18AC518-3E70-45AF-AFB2-6C6F5A75F549 Q38671442-ABC4465E-3F33-4B86-ABA5-BC7166F553FF Q38969032-2C00BAAC-6309-46A0-B420-319D7931FEF0 Q39166938-1ECBD0AE-DC26-4EE5-B248-2C96333F8B0C Q39261822-86D529DC-6648-4EA7-AAB1-D75BA4361801 Q39434973-0B94E1AC-09AE-4650-9109-110B5AF576DD Q40579653-205C74E1-86EC-4949-AB75-E8AF9EDB7D77 Q40688737-EB9F41F9-CE87-4F8C-98FD-9BAB58993724 Q40999568-B759BD40-25D7-4FB8-8778-1350759CA3D5 Q41380639-A5FAD068-5765-41E9-83E7-ABC58BD60F75 Q41584831-F3118935-B02C-4A83-AADF-B16322A88F52 Q41893086-6B8A6DD1-F521-4D4F-9C4D-969702DAFAA5 Q47417344-1B2284B5-6B69-4DCE-9DAD-19FD83A9E1B8 Q47606036-FA540FD4-A752-4817-BB00-F001C134A61C Q47674286-3CA9CC7F-8CCE-4699-888A-63F55419808E Q47707731-3FE27CF3-EC0B-4AAF-84DA-BA84D8E967E4 Q47928036-D35D95CD-3AEE-4BD3-82A5-FF14DB86BBB1 Q48110568-C134CDD7-C1D9-4438-A472-502FEB524C5A Q49819864-5196A944-959D-4019-BF16-BBA7FE36D9C1 Q50073076-5849AB37-E6C7-45C5-ACB7-AD3DC7D4ABF2 Q50131806-DC70C100-7249-4E7D-AAEE-354C3DF78397

P2860

MuSK IgG4 autoantibodies cause myasthenia gravis by inhibiting binding between MuSK and Lrp4.

http://www.wikidata.org/entity/Q37409458

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 02 December 2013

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

MuSK IgG4 autoantibodies cause ...... binding between MuSK and Lrp4.

@en

MuSK IgG4 autoantibodies cause ...... binding between MuSK and Lrp4.

@nl

type

label

MuSK IgG4 autoantibodies cause ...... binding between MuSK and Lrp4.

@en

MuSK IgG4 autoantibodies cause ...... binding between MuSK and Lrp4.

@nl

prefLabel

MuSK IgG4 autoantibodies cause ...... binding between MuSK and Lrp4.

@en

MuSK IgG4 autoantibodies cause ...... binding between MuSK and Lrp4.

@nl

P1433

Q37409458-323E7751-6603-49F4-AF0C-69FE72FF77F0

P1476

Q37409458-D22B4CD6-80B2-4DE1-A410-3BCF0506D2B0

P2093

Q37409458-07ABEA2D-BA6E-4BB8-AD26-8884737357AC

Q37409458-2E0D30A0-598E-4BC6-94E9-503DC9D69AF2

Q37409458-2F339A62-7674-47F4-940A-7B6BD34068D6

Q37409458-74B1D355-0038-4538-B7F3-00C6C2237218

Q37409458-8C227E17-C64B-492D-83D1-0449580FC257

Q37409458-CEBB610B-2E8D-4402-99CA-BE10AF390E01

Q37409458-D40811F8-58E1-4D71-B0EF-20A98AAA4747

Q37409458-D6856631-47A1-4141-82D3-FF3799BA5799

Q37409458-F2EC97AB-B4C8-4F52-BA2A-3D7716B85751

Q37409458-FE25EECB-3591-4735-957B-6070DC1C31CF

P2860

Q37409458-02AF7EF4-2850-4C67-BC4B-79A1CB63A054

Q37409458-0CB713C0-0B37-4803-9AA5-8DDD10F20B89

Q37409458-0CCBFE30-25C5-4A9A-9505-F8A03CC47702

Q37409458-0D2C13F8-0195-4411-89F5-3A3AB3D4893C

Q37409458-0D5B27A1-B227-46CD-88A0-0A4983EBC768

Q37409458-0E204471-D143-4424-80B5-189F269561A8

Q37409458-186884D5-8D97-4A3C-9149-F55CF597A0AA

Q37409458-228C6B3D-A818-4190-9501-C041E48212B1

Q37409458-32F65FD2-B6A8-4472-95F0-70D203089A99

Q37409458-43F85FAE-FFEF-4BAC-A58C-BD1FB4B26769

P304

Q37409458-D549B35F-8D35-489D-A5C8-5534DC7EA062

P31

Q37409458-4553A184-B683-4C25-88B3-64427D77D200

P356

Q37409458-E9495C8E-0AF2-4A63-8136-0340F967B191

P407

Q37409458-5D3F1A47-BECE-464F-A93D-027AACB61D2B

P433

Q37409458-A4C15C28-0566-47AE-8EB9-D5CA2FB9A3F1

P478

Q37409458-CE4F6786-F242-4F15-AD5E-A2467E0E233F

P50

Q37409458-045FD131-583D-47EF-A04F-F8C74D8B6FB6

Q37409458-1C7EEE37-9116-4FC5-A718-4FD91C1DDF5F

Q37409458-9E75E72C-0A26-4B49-AF25-F0A31F41BA27

Q37409458-C920BEB2-B830-41FB-B091-472C39F376DA

P577

Q37409458-86299B40-BB89-468E-ADC9-4EDD99D00D9A

P5875

Q37409458-43963F4B-F4EA-4112-B205-7EB2475A245D

P698

Q37409458-491A45DA-3B35-4569-99A7-3F6375026137

P921

Q37409458-50EB2A56-71EE-4DF4-AB6D-EEED3B536F93

Q37409458-F395031B-073F-4887-ACA0-52B4198D1653

P932

Q37409458-8A92BC9D-22E4-480B-872F-D71F338158D5

P356

PNAS.1313944110

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

MuSK IgG4 autoantibodies cause ...... binding between MuSK and Lrp4.

@en

P2093

Hans Vrolijk

http://www.w3.org/2001/XMLSchema#string

Jaap J Plomp

http://www.w3.org/2001/XMLSchema#string

Kirsten R Straasheijm

http://www.w3.org/2001/XMLSchema#string

Maartje G Huijbers

http://www.w3.org/2001/XMLSchema#string

Matthew B Friese

http://www.w3.org/2001/XMLSchema#string

Pauline Vogels

http://www.w3.org/2001/XMLSchema#string

Peter E Thijssen

http://www.w3.org/2001/XMLSchema#string

Rinse Klooster

http://www.w3.org/2001/XMLSchema#string

Steven J Burden

http://www.w3.org/2001/XMLSchema#string

Wei Zhang

http://www.w3.org/2001/XMLSchema#string

P2860

Receptor tyrosine kinase specific for the skeletal muscle lineage: expression in embryonic muscle, at the neuromuscular junction, and after injury

M-type phospholipase A2 receptor as target antigen in idiopathic membranous nephropathy

MuSK is required for anchoring acetylcholinesterase at the neuromuscular junction

Crystal structure of the MuSK tyrosine kinase: insights into receptor autoregulation

Main Immunogenic Region Structure Promotes Binding of Conformation-Dependent Myasthenia Gravis Autoantibodies, Nicotinic Acetylcholine Receptor Conformation Maturation, and Agonist Sensitivity

Auto-antibodies to the receptor tyrosine kinase MuSK in patients with myasthenia gravis without acetylcholine receptor antibodies

Induction, assembly, maturation and maintenance of a postsynaptic apparatus

Anti-LRP4 autoantibodies in AChR- and MuSK-antibody-negative myasthenia gravis

The muscle protein Dok-7 is essential for neuromuscular synaptogenesis

The receptor tyrosine kinase MuSK is required for neuromuscular junction formation in vivo

P304

20783-20788

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1073/PNAS.1313944110

http://www.w3.org/2001/XMLSchema#string

P407

P433

51

http://www.w3.org/2001/XMLSchema#string

P478

110

http://www.w3.org/2001/XMLSchema#string

P50

Jan J Verschuuren

Silvère M van der Maarel

P577

2013-12-02T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

259115166

http://www.w3.org/2001/XMLSchema#string

P698

24297891

http://www.w3.org/2001/XMLSchema#string

P921

myasthenia gravis

P932

3870730

http://www.w3.org/2001/XMLSchema#string