Targeted disruption of the peripheral-type benzodiazepine receptor gene inhibits steroidogenesis in the R2C Leydig tumor cell line
about
Cloning and characterization of PRAX-1. A new protein that specifically interacts with the peripheral benzodiazepine receptorCholesterol binding at the cholesterol recognition/ interaction amino acid consensus (CRAC) of the peripheral-type benzodiazepine receptor and inhibition of steroidogenesis by an HIV TAT-CRAC peptideTranslocator protein-mediated pharmacology of cholesterol transport and steroidogenesisBinding domain-driven intracellular trafficking of sterols for synthesis of steroid hormones, bile acids and oxysterolsTranslocator protein/peripheral benzodiazepine receptor is not required for steroid hormone biosynthesisSystemic administration of alcohol to adult rats inhibits leydig cell activity: Time course of effect and role of nitric oxideMolecular mechanisms mediating the effect of mono-(2-ethylhexyl) phthalate on hormone-stimulated steroidogenesis in MA-10 mouse tumor Leydig cellsTranscriptional regulation of translocator protein (Tspo) via a SINE B2-mediated natural antisense transcript in MA-10 Leydig cells.The mechanism of action of steroidogenic acute regulatory protein (StAR). StAR acts on the outside of mitochondria to stimulate steroidogenesis.PBR, StAR, and PKA: partners in cholesterol transport in steroidogenic cells.Regulation of the mitochondrial permeability transition pore by the outer membrane does not involve the peripheral benzodiazepine receptor (Translocator Protein of 18 kDa (TSPO)).Mechanisms controlling the function and life span of the corpus luteum.Estradiol modulates translocator protein (TSPO) and steroid acute regulatory protein (StAR) via protein kinase A (PKA) signaling in hypothalamic astrocytesCellular cholesterol delivery, intracellular processing and utilization for biosynthesis of steroid hormones.Liver fatty acid-binding protein and obesity.Injury-induced regulation of steroidogenic gene expression in the cerebellumMolecular imaging of microglia/macrophages in the brain.Peripheral benzodiazepine receptor/translocator protein global knock-out mice are viable with no effects on steroid hormone biosynthesis.Mitochondrial protein import and the genesis of steroidogenic mitochondriaNovel androstenetriol interacts with the mitochondrial translocator protein and controls steroidogenesis.Developmental expression of translocator protein/peripheral benzodiazepine receptor in reproductive tissuesPK11195 effect on steroidogenesis is not mediated through the translocator protein (TSPO).Tumor selective G2/M cell cycle arrest and apoptosis of epithelial and hematological malignancies by BBL22, a benzazepineMinireview: translocator protein (TSPO) and steroidogenesis: a reappraisal.Positron Emission Tomography studies with [11C]PBR28 in the Healthy Rodent Brain: Validating SUV as an Outcome Measure of NeuroinflammationConditional steroidogenic cell-targeted deletion of TSPO unveils a crucial role in viability and hormone-dependent steroid formation.Translocator protein (18 kDa) polymorphism (rs6971) explains in-vivo brain binding affinity of the PET radioligand [(18)F]-FEPPA.Non-vesicular sterol transport in cells.Activated macrophages in HIV encephalitis and a macaque model show increased [3H](R)-PK11195 binding in a PI3-kinase-dependent manner.Mitochondrial ion channels.The peripheral benzodiazepine receptor (Translocator protein 18kDa) in microglia: from pathology to imaging.The translocator protein (TSPO) ligand PK11195 induces apoptosis and cell cycle arrest and sensitizes to chemotherapy treatment in pre- and post-relapse neuroblastoma cell lines.Estradiol regulation of progesterone synthesis in the brainDrug ligand-induced activation of translocator protein (TSPO) stimulates steroid production by aged brown Norway rat Leydig cellsPhorbol-12-myristate 13-acetate acting through protein kinase Cepsilon induces translocator protein (18-kDa) TSPO gene expressionSingle-step high-yield radiosynthesis and evaluation of a sensitive 18F-labeled ligand for imaging brain peripheral benzodiazepine receptors with PET.Imaging microglial activation during neuroinflammation and Alzheimer's disease.Cholesterol transport in steroid biosynthesis: role of protein-protein interactions and implications in disease states.The role of PBR/TSPO in steroid biosynthesis challenged.Axonal regeneration and neuroinflammation: roles for the translocator protein 18 kDa.
P2860
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P2860
Targeted disruption of the peripheral-type benzodiazepine receptor gene inhibits steroidogenesis in the R2C Leydig tumor cell line
description
1997 nî lūn-bûn
@nan
1997 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
name
Targeted disruption of the per ...... the R2C Leydig tumor cell line
@ast
Targeted disruption of the per ...... the R2C Leydig tumor cell line
@en
Targeted disruption of the per ...... the R2C Leydig tumor cell line
@nl
type
label
Targeted disruption of the per ...... the R2C Leydig tumor cell line
@ast
Targeted disruption of the per ...... the R2C Leydig tumor cell line
@en
Targeted disruption of the per ...... the R2C Leydig tumor cell line
@nl
prefLabel
Targeted disruption of the per ...... the R2C Leydig tumor cell line
@ast
Targeted disruption of the per ...... the R2C Leydig tumor cell line
@en
Targeted disruption of the per ...... the R2C Leydig tumor cell line
@nl
P2093
P2860
P3181
P356
P1476
Targeted disruption of the per ...... the R2C Leydig tumor cell line
@en
P2093
P2860
P304
32129-32135
P3181
P356
10.1074/JBC.272.51.32129
P407
P577
1997-12-01T00:00:00Z