Targeting of the c-Abl tyrosine kinase to mitochondria in endoplasmic reticulum stress-induced apoptosis
about
Werner syndrome protein phosphorylation by abl tyrosine kinase regulates its activity and distributionEndoplasmic reticulum stress: cell life and death decisions.Regulation of mitochondrial functions by protein phosphorylation and dephosphorylationCharacterization of a myeloid tyrosine phosphatase, Lyp, and its role in the Bcr-Abl signal transduction pathwayProtein-tyrosine phosphatase 1B potentiates IRE1 signaling during endoplasmic reticulum stressCell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunitiesDefying c-Abl signaling circuits through small allosteric compounds.Aph2, a protein with a zf-DHHC motif, interacts with c-Abl and has pro-apoptotic activity.c-Abl inhibition delays motor neuron degeneration in the G93A mouse, an animal model of amyotrophic lateral sclerosis.Assay development and high-throughput screening of small molecular c-Abl kinase activators.Protein Lipidation As a Regulator of Apoptotic Calcium Release: Relevance to Cancer.Human MUC1 carcinoma-associated protein confers resistance to genotoxic anticancer agents.Caspase-12 mediates carbon tetrachloride-induced hepatocyte apoptosis in mice.Small-molecule inhibition of inflammatory β-cell death.Orchestrating the unfolded protein response in health and disease.Mitochondria as a target for inducing death of malignant hematopoietic cells.Misfolded proteins, endoplasmic reticulum stress and neurodegeneration.Selective targeting of c-Abl via a cryptic mitochondrial targeting signal activated by cellular redox status in leukemic and breast cancer cells.Endoplasmic reticulum stress and apoptosis.Mig6 is a sensor of EGF receptor inactivation that directly activates c-Abl to induce apoptosis during epithelial homeostasisPhosphorylated proteins of the mammalian mitochondrial ribosome: implications in protein synthesis.N-myristoylated c-Abl tyrosine kinase localizes to the endoplasmic reticulum upon binding to an allosteric inhibitor.Potential utility of small tyrosine kinase inhibitors in the treatment of diabetes.Oxidative Stress, DNA Damage, and c-Abl Signaling: At the Crossroad in Neurodegenerative Diseases?Targeting malignant mitochondria with therapeutic peptides.Does the small tyrosine kinase inhibitor Imatinib mesylate counteract diabetes by affecting pancreatic islet amyloidosis and fibrosis?Tyrosine kinase inhibitors as novel drugs for the treatment of diabetes.The essential biology of the endoplasmic reticulum stress response for structural and computational biologists.Melatonin and endoplasmic reticulum stress: relation to autophagy and apoptosis.Homocysteine induces PUMA-mediated mitochondrial apoptosis in SH-SY5Y cells.Targeting ABL-IRE1α Signaling Spares ER-Stressed Pancreatic β Cells to Reverse Autoimmune Diabetes.Morphology of mitochondrial permeability transition: morphometric volumetry in apoptotic cells.Imatinib mesylate reduces endoplasmic reticulum stress and induces remission of diabetes in db/db mice.Enterovirus 71 triggering of neuronal apoptosis through activation of Abl-Cdk5 signalling.Phosphorylation of Helicobacter pylori CagA by c-Abl leads to cell motility.Endoplasmic reticulum stress signaling transmitted by ATF6 mediates apoptosis during muscle development.Overexpression of kinase-negative protein kinase Cdelta in pancreatic beta-cells protects mice from diet-induced glucose intolerance and beta-cell dysfunction.Opposing roles of KIT and ABL1 in the therapeutic response of gastrointestinal stromal tumor (GIST) cells to imatinib mesylate.A pervasive role for MIG6 in restraining cell proliferation.Mechanistic investigation of imatinib-induced cardiac toxicity and the involvement of c-Abl kinase.
P2860
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P2860
Targeting of the c-Abl tyrosine kinase to mitochondria in endoplasmic reticulum stress-induced apoptosis
description
2001 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2001
@ast
im September 2001 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2001/09/01)
@sk
vědecký článek publikovaný v roce 2001
@cs
wetenschappelijk artikel (gepubliceerd op 2001/09/01)
@nl
наукова стаття, опублікована у вересні 2001
@uk
مقالة علمية (نشرت في سبتمبر 2001)
@ar
name
Targeting of the c-Abl tyrosin ...... culum stress-induced apoptosis
@ast
Targeting of the c-Abl tyrosin ...... culum stress-induced apoptosis
@en
Targeting of the c-Abl tyrosin ...... culum stress-induced apoptosis
@nl
type
label
Targeting of the c-Abl tyrosin ...... culum stress-induced apoptosis
@ast
Targeting of the c-Abl tyrosin ...... culum stress-induced apoptosis
@en
Targeting of the c-Abl tyrosin ...... culum stress-induced apoptosis
@nl
prefLabel
Targeting of the c-Abl tyrosin ...... culum stress-induced apoptosis
@ast
Targeting of the c-Abl tyrosin ...... culum stress-induced apoptosis
@en
Targeting of the c-Abl tyrosin ...... culum stress-induced apoptosis
@nl
P2093
P2860
P921
P3181
P1476
Targeting of the c-Abl tyrosin ...... culum stress-induced apoptosis
@en
P2093
S. Kharbanda
P2860
P304
P3181
P356
10.1128/MCB.21.18.6233-6242.2001
P407
P577
2001-09-01T00:00:00Z