Janus kinase 2, an early target of alpha 7 nicotinic acetylcholine receptor-mediated neuroprotection against Abeta-(1-42) amyloid
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Nicotine exposure and bronchial epithelial cell nicotinic acetylcholine receptor expression in the pathogenesis of lung cancerAmyloid-beta neurotoxicity is mediated by FISH adapter protein and ADAM12 metalloprotease activityEmerging preclinical pharmacological targets for Parkinson's diseaseModulatory effects of α7 nAChRs on the immune system and its relevance for CNS disordersInterleukin-3 prevents neuronal death induced by amyloid peptideNicotinic acetylcholine receptor signalling: roles in Alzheimer's disease and amyloid neuroprotection.Alpha7 nicotinic acetylcholine receptor: a link between inflammation and neurodegeneration.Vagus nerve through α7 nAChR modulates lung infection and inflammation: models, cells, and signalsNicotine: specific role in angiogenesis, proliferation and apoptosis.A new IRAK-M-mediated mechanism implicated in the anti-inflammatory effect of nicotine via α7 nicotinic receptors in human macrophages.Docosahexaenoic acid protects from dendritic pathology in an Alzheimer's disease mouse modelFunction of partially duplicated human α77 nicotinic receptor subunit CHRFAM7A gene: potential implications for the cholinergic anti-inflammatory response.A type-II positive allosteric modulator of α7 nAChRs reduces brain injury and improves neurological function after focal cerebral ischemia in rats.Scientific and clinical challenges in sepsis.α7 Nicotinic Receptor Promotes the Neuroprotective Functions of Astrocytes against Oxaliplatin NeurotoxicityA case-control study of a sex-specific association between a 15q25 variant and lung cancer risk.Functional Impact of 14 Single Nucleotide Polymorphisms Causing Missense Mutations of Human α7 Nicotinic Receptor.The alpha7 nicotinic acetylcholine receptor as a pharmacological target for inflammation.Lipopolysaccharide upregulates α7 acetylcholine receptors: stimulation with GTS-21 mitigates growth arrest of macrophages and improves survival in burned miceRisk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5.Coupling of ionic events to protein kinase signaling cascades upon activation of alpha7 nicotinic receptor: cooperative regulation of alpha2-integrin expression and Rho kinase activity.Neuronal nicotinic receptors as novel targets for inflammation and neuroprotection: mechanistic considerations and clinical relevance.Application of alpha7 nicotinic acetylcholine receptor agonists in inflammatory diseases: an overview.Alpha7 nicotinic receptors as novel therapeutic targets for inflammation-based diseases.The role of vagus nerve overactivity in the increased incidence of pneumonia following traumatic brain injury.The Binding Receptors of Aβ: an Alternative Therapeutic Target for Alzheimer's Disease.Functionally significant nicotine acetylcholine receptor subunit α5 promoter haplotypes are associated with susceptibility to lung cancer in Chinese.Alpha7 nicotinic receptors as therapeutic targets for Parkinson's disease.Gx-50 Inhibits Neuroinflammation via α7 nAChR Activation of the JAK2/STAT3 and PI3K/AKT Pathways.Neuroprotective Effect of Nanodiamond in Alzheimer's Disease Rat Model: a Pivotal Role for Modulating NF-κB and STAT3 Signaling.Possible neuroprotective property of nicotinic acetylcholine receptors in association with predominant upregulation of glial cell line-derived neurotrophic factor in astrocytes.The beta-amyloid protein of Alzheimer's disease binds to membrane lipids but does not bind to the alpha7 nicotinic acetylcholine receptor.ACh receptors link two signaling pathways to neuroprotection against glutamate-induced excitotoxicity in isolated RGCs.α7 Nicotinic Acetylcholine Receptor Stimulation Attenuates Neuroinflammation through JAK2-STAT3 Activation in Murine Models of Intracerebral Hemorrhage.Cholinergic receptor pathways involved in apoptosis, cell proliferation and neuronal differentiation.α7 nicotinic acetylcholine receptor agonism confers neuroprotection through GSK-3β inhibition in a mouse model of intracerebral hemorrhage.Spinal astrocytes stimulated by tumor necrosis factor-α and/or interferon-γ attenuate connexin 43-gap junction via c-jun terminal kinase activity.Functional Consequences of CHRNA7 Copy-Number Alterations in Induced Pluripotent Stem Cells and Neural Progenitor Cells.The role of alpha7 nicotinic acetylcholine receptors in inflammatory bowel disease: involvement of different cellular pathways.Nicotine prevents synaptic impairment induced by amyloid-β oligomers through α7-nicotinic acetylcholine receptor activation.
P2860
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P2860
Janus kinase 2, an early target of alpha 7 nicotinic acetylcholine receptor-mediated neuroprotection against Abeta-(1-42) amyloid
description
2002 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2002
@ast
im November 2002 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2002/11/22)
@sk
vědecký článek publikovaný v roce 2002
@cs
wetenschappelijk artikel (gepubliceerd op 2002/11/22)
@nl
наукова стаття, опублікована в листопаді 2002
@uk
name
Janus kinase 2, an early targe ...... n against Abeta-(1-42) amyloid
@ast
Janus kinase 2, an early targe ...... n against Abeta-(1-42) amyloid
@en
Janus kinase 2, an early targe ...... n against Abeta-(1-42) amyloid
@nl
type
label
Janus kinase 2, an early targe ...... n against Abeta-(1-42) amyloid
@ast
Janus kinase 2, an early targe ...... n against Abeta-(1-42) amyloid
@en
Janus kinase 2, an early targe ...... n against Abeta-(1-42) amyloid
@nl
prefLabel
Janus kinase 2, an early targe ...... n against Abeta-(1-42) amyloid
@ast
Janus kinase 2, an early targe ...... n against Abeta-(1-42) amyloid
@en
Janus kinase 2, an early targe ...... n against Abeta-(1-42) amyloid
@nl
P2093
P356
P1476
Janus kinase 2, an early targe ...... n against Abeta-(1-42) amyloid
@en
P2093
Mario B. Marrero
Merouane Bencherif
P304
44920–44924
P356
10.1074/JBC.M204610200
P407
P577
2002-11-22T00:00:00Z