Comparative peptide binding studies of the PABC domains from the ubiquitin-protein isopeptide ligase HYD and poly(A)-binding protein. Implications for HYD function
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Structural basis of binding of P-body-associated proteins GW182 and ataxin-2 by the Mlle domain of poly(A)-binding proteinAtaxin-2 interacts with the DEAD/H-box RNA helicase DDX6 and interferes with P-bodies and stress granulesMolecular basis of eRF3 recognition by the MLLE domain of poly(A)-binding proteinThe BTG2 protein is a general activator of mRNA deadenylationPoly(A) nuclease interacts with the C-terminal domain of polyadenylate-binding protein domain from poly(A)-binding proteinMechanism of mRNA deadenylation: evidence for a molecular interplay between translation termination factor eRF3 and mRNA deadenylasesHuman TOB, an antiproliferative transcription factor, is a poly(A)-binding protein-dependent positive regulator of cytoplasmic mRNA deadenylationLa-Related Protein 4 Binds Poly(A), Interacts with the Poly(A)-Binding Protein MLLE Domain via a Variant PAM2w Motif, and Can Promote mRNA StabilityA mechanism of translational repression by competition of Paip2 with eIF4G for poly(A) binding protein (PABP) binding.Mammalian hyperplastic discs homolog EDD regulates miRNA-mediated gene silencingRegulation of hedgehog Ligand Expression by the N-End Rule Ubiquitin-Protein Ligase Hyperplastic Discs and the Drosophila GSK3β Homologue, Shaggy.Evidence providing new insights into TOB-promoted deadenylation and supporting a link between TOB's deadenylation-enhancing and antiproliferative activities.The MLLE domain of the ubiquitin ligase UBR5 binds to its catalytic domain to regulate substrate binding.Use of a Conditional Ubr5 Mutant Allele to Investigate the Role of an N-End Rule Ubiquitin-Protein Ligase in Hedgehog Signalling and Embryonic Limb Development.The association of a La module with the PABP-interacting motif PAM2 is a recurrent evolutionary process that led to the neofunctionalization of La-related proteins.BTG2 bridges PABPC1 RNA-binding domains and CAF1 deadenylase to control cell proliferationBTG/TOB factors impact deadenylases.Mammalian ataxin-2 modulates translation control at the pre-initiation complex via PI3K/mTOR and is induced by starvation.
P2860
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P2860
Comparative peptide binding studies of the PABC domains from the ubiquitin-protein isopeptide ligase HYD and poly(A)-binding protein. Implications for HYD function
description
2006 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի մայիսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
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artículu científicu espublizáu en 2006
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im Mai 2006 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 2006/05/19)
@sk
vědecký článek publikovaný v roce 2006
@cs
wetenschappelijk artikel (gepubliceerd op 2006/05/19)
@nl
наукова стаття, опублікована в травні 2006
@uk
name
Comparative peptide binding st ...... Implications for HYD function
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Comparative peptide binding st ...... Implications for HYD function
@en
Comparative peptide binding st ...... Implications for HYD function
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type
label
Comparative peptide binding st ...... Implications for HYD function
@ast
Comparative peptide binding st ...... Implications for HYD function
@en
Comparative peptide binding st ...... Implications for HYD function
@nl
prefLabel
Comparative peptide binding st ...... Implications for HYD function
@ast
Comparative peptide binding st ...... Implications for HYD function
@en
Comparative peptide binding st ...... Implications for HYD function
@nl
P2093
P2860
P3181
P356
P1476
Comparative peptide binding st ...... Implications for HYD function
@en
P2093
Ann-Bin Shyu
Gregory De Crescenzo
Laurent Volpon
Nadeem Siddiqui
Nadia S. Lim
Olivia Groover
Tsung-Cheng Chang
P2860
P304
14376–14382
P3181
P356
10.1074/JBC.M600307200
P407
P577
2006-05-19T00:00:00Z