Association of Bax and Bak homo-oligomers in mitochondria. Bax requirement for Bak reorganization and cytochrome c release
about
Interaction of F1L with the BH3 domain of Bak is responsible for inhibiting vaccinia-induced apoptosisProapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins.The tyrosine kinase Lck is a positive regulator of the mitochondrial apoptosis pathway by controlling Bak expressionMAP-1 is a mitochondrial effector of Bax.Oligomeric Bax is a component of the putative cytochrome c release channel MAC, mitochondrial apoptosis-induced channelLoss of Bif-1 suppresses Bax/Bak conformational change and mitochondrial apoptosisc-Myc augments gamma irradiation-induced apoptosis by suppressing Bcl-XLBax regulates primary necrosis through mitochondrial dynamicsAberrant Apoptotic Response of Colorectal Cancer Cells to Novel Nucleoside AnaloguesRole of pigment epithelium-derived factor (PEDF) in arsenic-induced cell apoptosis of liver and brain in a rat modelApoptosis induced by Ginkgo biloba (EGb761) in melanoma cells is Mcl-1-dependentAuto-activation of the apoptosis protein Bax increases mitochondrial membrane permeability and is inhibited by Bcl-2Bax-dependent regulation of Bak by voltage-dependent anion channel 2.RNA silencing of Mcl-1 enhances ABT-737-mediated apoptosis in melanoma: role for a caspase-8-dependent pathway.Mitochondrial ion channels as therapeutic targets.Mitochondrial ceramide-rich macrodomains functionalize Bax upon irradiation.Identification of a conserved anti-apoptotic protein that modulates the mitochondrial apoptosis pathway.Mutual regulation of Bcl-2 proteins independent of the BH3 domain as shown by the BH3-lacking protein Bcl-x(AK).Inhibition of Bak activation by VDAC2 is dependent on the Bak transmembrane anchorCytomegalovirus cell death suppressor vMIA blocks Bax- but not Bak-mediated apoptosis by binding and sequestering Bax at mitochondria.Requirement of p53 targets in chemosensitization of colonic carcinoma to death ligand therapy.Oligomerization of the mitochondrial protein voltage-dependent anion channel is coupled to the induction of apoptosisIdentification of subtilase cytotoxin (SubAB) receptors whose signaling, in association with SubAB-induced BiP cleavage, is responsible for apoptosis in HeLa cells.Regulated cell death in AKI.DAP1, a negative regulator of autophagy, controls SubAB-mediated apoptosis and autophagy.Deerpox virus encodes an inhibitor of apoptosis that regulates Bak and Bax.Vinblastine-induced apoptosis is mediated by discrete alterations in subcellular location, oligomeric structure, and activation status of specific Bcl-2 family members2,5-hexanedione induced apoptosis in mesenchymal stem cells from rat bone marrow via mitochondria-dependent caspase-3 pathway.The Bcl-2 family: roles in cell survival and oncogenesis.Key role for Bak activation and Bak-Bax interaction in the apoptotic response to vinblastinec-Myc primed mitochondria determine cellular sensitivity to TRAIL-induced apoptosis.Regulation of caspase-9 activity by differential binding to the apoptosome complexMEK1/2 inhibitors sensitize Bcr/Abl+ human leukemia cells to the dual Abl/Src inhibitor BMS-354/825Bax dimerizes via a symmetric BH3:groove interface during apoptosisA three-helix homo-oligomerization domain containing BH3 and BH1 is responsible for the apoptotic activity of Bax.Regulation of subtilase cytotoxin-induced cell death by an RNA-dependent protein kinase-like endoplasmic reticulum kinase-dependent proteasome pathway in HeLa cellsBax monomers form dimer units in the membrane that further self-assemble into multiple oligomeric speciesRecent progress in studies of arterivirus- and coronavirus-host interactionsConformational control of Bax localization and apoptotic activity by Pro168.Zerumbone causes Bax- and Bak-mediated apoptosis in human breast cancer cells and inhibits orthotopic xenograft growth in vivo.
P2860
Q24302248-D47B56AC-E850-4E5C-B35D-C3FE737F0308Q24302494-22299034-E274-422A-BC9E-03459E7AD89CQ24317331-4FE81727-1046-49C2-B40A-847F523E3218Q24337383-C24F0032-0630-41C4-AEF7-D3ABC71395FDQ24523479-6D34B8F2-DE79-4F52-8F25-E0ABCEFFD934Q24534937-D923849D-2000-45A7-BAC4-6F45EDD5422FQ24653312-106305EE-33FD-4A7A-9B35-61E0F46BA29BQ28506109-36F7C17C-A1C7-4D5B-9962-05299417F253Q28548303-E2DA257E-1C93-43C4-A6D5-719DFF40B8A1Q28577155-901A766B-B536-466F-B256-88E255F3610CQ28649832-C8D2CE68-2E32-4421-9877-D4723D943D29Q30493313-4630598C-F2C2-4E82-82FA-923F36A69F72Q33212700-3AA2218B-6936-4278-BC8E-562B37DC95E8Q33494047-29540926-C23C-45A7-B70A-3AF2E4E01EE0Q33857921-F2A7BC73-FD6A-4D79-A973-03215A6E46B6Q33939529-233C7177-F281-476F-B3E2-F6A8BDEE12C0Q34043049-59451B9A-7379-49E3-8120-30B2599D79D3Q34233598-02C9D81E-98CB-48F7-8A70-F91EA3ADB526Q34299265-DCE5A639-9AFA-4E29-9EE2-1D721FB5D7F4Q34330920-F1540556-4976-4C09-9130-4E7A290CC9C2Q34390964-CDB4DBE8-070F-4701-8333-5C0C32DEE8BEQ34416275-AE5F96D8-276D-41E0-9162-C31364C91C52Q34529462-6C28B0E5-F949-46A6-8089-08277ACFE1D4Q34568839-9364416F-B98B-4151-8461-C7B6EA05FD41Q34596057-FE55F168-5DC5-4E58-873A-E5D75C89A0ECQ34741839-43B90014-C1DD-4647-B174-FA0396745D38Q35160453-B74F20B7-0A0E-4CF0-A514-2E0C49647A8FQ35571766-6CF71897-BB97-401E-B36A-AB185F6F8EF1Q35591695-F303CB3D-2E8F-446F-823C-118E5F59A3BFQ35747444-87DAE4E6-DC54-45AE-9580-09AC031CE876Q35752871-FD7D6F3D-2445-4EC1-8DC7-05576C5F2392Q35792765-1CF5F2D3-1CE5-468F-9A93-F37B958CE436Q35804449-0CFDE059-2186-4B6A-A1BA-736DBAEA6D85Q35840528-28B5880C-26DD-4481-8075-1F94EE6265E1Q35917067-85017A09-C706-472B-9C9C-B01185E72B9CQ35944091-598A9B6C-114C-4B62-952A-B79A9F4A3019Q36018810-E65384ED-1F33-4F8E-A54D-4D212C8C2175Q36096411-E65E4A6F-7265-4D21-9B02-276FE6751C33Q36321947-6862E521-6D23-4FB6-905C-B201C8D23F1CQ36356930-352846EE-F739-4B25-B58F-6B17CE6A0E25
P2860
Association of Bax and Bak homo-oligomers in mitochondria. Bax requirement for Bak reorganization and cytochrome c release
description
2003 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2003
@ast
im Februar 2003 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2003/02/14)
@sk
vědecký článek publikovaný v roce 2003
@cs
wetenschappelijk artikel (gepubliceerd op 2003/02/14)
@nl
наукова стаття, опублікована в лютому 2003
@uk
name
Association of Bax and Bak hom ...... ation and cytochrome c release
@ast
Association of Bax and Bak hom ...... ation and cytochrome c release
@en
Association of Bax and Bak hom ...... ation and cytochrome c release
@nl
type
label
Association of Bax and Bak hom ...... ation and cytochrome c release
@ast
Association of Bax and Bak hom ...... ation and cytochrome c release
@en
Association of Bax and Bak hom ...... ation and cytochrome c release
@nl
prefLabel
Association of Bax and Bak hom ...... ation and cytochrome c release
@ast
Association of Bax and Bak hom ...... ation and cytochrome c release
@en
Association of Bax and Bak hom ...... ation and cytochrome c release
@nl
P2093
P3181
P356
P1476
Association of Bax and Bak hom ...... ation and cytochrome c release
@en
P2093
Kurt Degenhardt
Manjeri A. Venkatachalam
Margarita Mikhailova
Pothana Saikumar
Valery Mikhailov
P304
P3181
P356
10.1074/JBC.M203392200
P407
P50
P577
2003-02-14T00:00:00Z