Cbl-b is a negative regulator of receptor clustering and raft aggregation in T cells
about
Ubiquitylation-dependent downregulation of Nck regulates its functional activityCbl-b positively regulates Btk-mediated activation of phospholipase C-gamma2 in B cellsE3 ubiquitin ligases and their control of T cell autoreactivityUbiquitin in the immune systemThe Novel PKCθ from Benchtop to ClinicRegulation of T cell receptor-induced activation of the Ras-ERK pathway by diacylglycerol kinase zetaVav2 activates c-fos serum response element and CD69 expression but negatively regulates nuclear factor of activated T cells and interleukin-2 gene activation in T lymphocyteThe Cbl interactome and its functionsControlling NF-kappaB activation in T cells by costimulatory receptorsThe non-receptor tyrosine kinase Syk is a target of Cbl-mediated ubiquitylation upon B-cell receptor stimulation.Does antigen masking by ubiquitin chains protect from the development of autoimmune diseases?Negative regulation of Lyn protein-tyrosine kinase by c-Cbl ubiquitin-protein ligase in Fc epsilon RI-mediated mast cell activationThe PI-3 kinase/Akt pathway and T cell activation: pleiotropic pathways downstream of PIP3ATP-binding cassette transporter G1 negatively regulates thymocyte and peripheral lymphocyte proliferation.Ubiquitylation-dependent negative regulation of WASp is essential for actin cytoskeleton dynamicsSynergistic signals for natural cytotoxicity are required to overcome inhibition by c-Cbl ubiquitin ligaseCbl enforces Vav1 dependence and a restricted pathway of T cell developmentE3 ubiquitin ligase Cbl-b in innate and adaptive immunity.Vav-Rac1-mediated activation of the c-Jun N-terminal kinase/c-Jun/AP-1 pathway plays a major role in stimulation of the distal NFAT site in the interleukin-2 gene promoterProteolysis-independent regulation of PI3K by Cbl-b-mediated ubiquitination in T cells.Differential expression and signaling of CBL and CBL-B in BCR/ABL transformed cells.p85beta phosphoinositide 3-kinase regulates CD28 coreceptor functionAbrogating Cbl-b in effector CD8(+) T cells improves the efficacy of adoptive therapy of leukemia in mice.Cbl: many adaptations to regulate protein tyrosine kinases.Cbl-b regulates airway mucosal tolerance to aeroallergen.Beyond the RING: CBL proteins as multivalent adapters.Adoptive transfer of siRNA Cblb-silenced CD8+ T lymphocytes augments tumor vaccine efficacy in a B16 melanoma modelVav1 fine tunes p53 control of apoptosis versus proliferation in breast cancerKnockout mice: a paradigm shift in modern immunology.Positive and negative regulation of T-cell activation by adaptor proteins.Understanding Rho/Rac biology in T-cells using animal models.The regulation of actin remodeling during T-cell-APC conjugate formation.A model of an integrated immune system pathway in Homo sapiens and its interaction with superantigen producing expression regulatory pathway in Staphylococcus aureus: comparing behavior of pathogen perturbed and unperturbed pathwayThe roles of membrane microdomains (rafts) in T cell activation.Scaffolding of antigen receptors for immunogenic versus tolerogenic signaling.T-lymphocyte signalling in systemic lupus erythematosus: a lipid raft perspective.Immune synapse formation requires ZAP-70 recruitment by ezrin and CD43 removal by moesin.c-Cbl and Cbl-b ubiquitin ligases: substrate diversity and the negative regulation of signalling responses.Vav1/Rac-dependent actin cytoskeleton reorganization is required for lipid raft clustering in T cellsT cell development and T cell responses in mice with mutations affecting tyrosines 292 or 315 of the ZAP-70 protein tyrosine kinase.
P2860
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P2860
Cbl-b is a negative regulator of receptor clustering and raft aggregation in T cells
description
2000 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2000
@ast
im Oktober 2000 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2000/10/01)
@sk
vědecký článek publikovaný v roce 2000
@cs
wetenschappelijk artikel (gepubliceerd op 2000/10/01)
@nl
наукова стаття, опублікована в жовтні 2000
@uk
مقالة علمية (نشرت في أكتوبر 2000)
@ar
name
Cbl-b is a negative regulator of receptor clustering and raft aggregation in T cells
@ast
Cbl-b is a negative regulator of receptor clustering and raft aggregation in T cells
@en
Cbl-b is a negative regulator of receptor clustering and raft aggregation in T cells
@nl
type
label
Cbl-b is a negative regulator of receptor clustering and raft aggregation in T cells
@ast
Cbl-b is a negative regulator of receptor clustering and raft aggregation in T cells
@en
Cbl-b is a negative regulator of receptor clustering and raft aggregation in T cells
@nl
prefLabel
Cbl-b is a negative regulator of receptor clustering and raft aggregation in T cells
@ast
Cbl-b is a negative regulator of receptor clustering and raft aggregation in T cells
@en
Cbl-b is a negative regulator of receptor clustering and raft aggregation in T cells
@nl
P2093
P921
P3181
P1433
P1476
Cbl-b is a negative regulator of receptor clustering and raft aggregation in T cells
@en
P2093
C Krawczyk
D Bouchard
I Kozieradzki
K Bachmaier
S B Snapper
P304
P3181
P356
10.1016/S1074-7613(00)00046-7
P407
P577
2000-10-01T00:00:00Z