Ubiquitylation-dependent negative regulation of WASp is essential for actin cytoskeleton dynamics - Wikidata - awgldk - TriplyDB

Ubiquitylation-dependent negative regulation of WASp is essential for actin cytoskeleton dynamics

Ubiquitylation-dependent negative regulation of WASp is essential for actin cytoskeleton dynamics

http://www.wikidata.org/entity/Q30524705

about

Ubiquitylation-dependent downregulation of Nck regulates its functional activity Under lock and key: spatiotemporal regulation of WASP family proteins coordinates separate dynamic cellular processes Actin cytoskeletal defects in immunodeficiency Molecular difference between WASP and N-WASP critical for chemotaxis of T-cells towards SDF-1α.WASp family verprolin-homologous protein-2 (WAVE2) and Wiskott-Aldrich syndrome protein (WASp) engage in distinct downstream signaling interactions at the T cell antigen receptor site Disease-associated missense mutations in the EVH1 domain disrupt intrinsic WASp function causing dysregulated actin dynamics and impaired dendritic cell migration.Tyrosine phosphorylation of WIP releases bound WASP and impairs podosome assembly in macrophages Wiskott-Aldrich syndrome: a comprehensive review.Current and emerging treatment options for Wiskott-Aldrich syndrome.E3 ubiquitin ligase Cbl-b in innate and adaptive immunity.Actin foci facilitate activation of the phospholipase C-γ in primary T lymphocytes via the WASP pathway Identification of a novel regulatory sequence of actin nucleation promoting factor encoded by Autographa californica multiple nucleopolyhedrovirus.Coordinate control of cytoskeletal remodeling and calcium mobilization during T-cell activation A conformational change within the WAVE2 complex regulates its degradation following cellular activation T cell antigen receptor activation and actin cytoskeleton remodeling.Cbl-family proteins as regulators of cytoskeleton-dependent phenomena.Wiskott-Aldrich syndrome protein--dynamic regulation of actin homeostasis: from activation through function and signal termination in T lymphocytes.Signal Integration during T Lymphocyte Activation and Function: Lessons from the Wiskott-Aldrich Syndrome.Cbl ubiquitin ligases mediate the inhibition of natural killer cell activity Dephosphorylation of the adaptor LAT and phospholipase C-γ by SHP-1 inhibits natural killer cell cytotoxicity.Rho GTPases as therapeutic targets in cancer (Review).Immune Regulation by Ubiquitin Tagging as Checkpoint Code.Wiskott-Aldrich syndrome protein: Emerging mechanisms in immunity.Actin retrograde flow controls natural killer cell response by regulating the conformation state of SHP-1.Triple-color FRET analysis reveals conformational changes in the WIP-WASp actin-regulating complex.

P2860

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P2860

Ubiquitylation-dependent negative regulation of WASp is essential for actin cytoskeleton dynamics

http://www.wikidata.org/entity/Q30524705

description

2012 nî lūn-bûn

@nan

2012 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի հունիսին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

@zh-hant

2012年論文

@zh-hk

2012年論文

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2012年論文

@zh-tw

2012年论文

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name

Ubiquitylation-dependent negat ...... or actin cytoskeleton dynamics

@ast

Ubiquitylation-dependent negat ...... or actin cytoskeleton dynamics

@en

type

label

Ubiquitylation-dependent negat ...... or actin cytoskeleton dynamics

@ast

Ubiquitylation-dependent negat ...... or actin cytoskeleton dynamics

@en

prefLabel

Ubiquitylation-dependent negat ...... or actin cytoskeleton dynamics

@ast

Ubiquitylation-dependent negat ...... or actin cytoskeleton dynamics

@en

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Molecular and Cellular Biology

P1476

Ubiquitylation-dependent negat ...... or actin cytoskeleton dynamics

@en

P2093

Ahuvit David

http://www.w3.org/2001/XMLSchema#string

Barak Reicher

http://www.w3.org/2001/XMLSchema#string

Maor H Pauker

http://www.w3.org/2001/XMLSchema#string

Noah Joseph

http://www.w3.org/2001/XMLSchema#string

Orly Perl

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P2860

Mutations that cause the Wiskott-Aldrich syndrome impair the interaction of Wiskott-Aldrich syndrome protein (WASP) with WASP interacting protein

Protein-tyrosine kinase and GTPase signals cooperate to phosphorylate and activate Wiskott-Aldrich syndrome protein (WASP)/neuronal WASP

Recruitment and activation of PLCgamma1 in T cells: a new insight into old domains

WIP, a protein associated with wiskott-aldrich syndrome protein, induces actin polymerization and redistribution in lymphoid cells

Cooperative interactions at the SLP-76 complex are critical for actin polymerization

Wiskott-Aldrich syndrome protein physically associates with Nck through Src homology 3 domains

T cell activation

Characterization of Wiskott-Aldrich syndrome (WAS) mutants using Saccharomyces cerevisiae

Cbl-b is a negative regulator of receptor clustering and raft aggregation in T cells

β1 integrins regulate fibroblast chemotaxis through control of N-WASP stability.

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3153-3163

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scholarly article

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10.1128/MCB.00161-12

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15

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32

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P50

Mira Barda-Saad

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2012-06-04T00:00:00Z

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22665495

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P921

actin cytoskeleton

P932

3434509

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