PTIP promotes chromatin changes critical for immunoglobulin class switch recombination
about
BCR-signalling synergizes with TLR-signalling for induction of AID and immunoglobulin class-switching through the non-canonical NF-κB pathwayEpigenetics of Peripheral B-Cell Differentiation and the Antibody ResponseEpigenetic Codes Programing Class Switch RecombinationMechanisms of gene activation and repression by Pax proteins in the developing kidneyModeling the study of DNA damage responses in miceIgH chain class switch recombination: mechanism and regulationAID targeting is dependent on RNA polymerase II pausing.53BP1 mediates productive and mutagenic DNA repair through distinct phosphoprotein interactions.The histone methyltransferase MMSET regulates class switch recombinationA PTIP-PA1 subcomplex promotes transcription for IgH class switching independently from the associated MLL3/MLL4 methyltransferase complexUniform, optimal signal processing of mapped deep-sequencing data.Epigenetic control of the immune system: a lesson from Kabuki syndrome.Generation and repair of AID-initiated DNA lesions in B lymphocytes.ATM increases activation-induced cytidine deaminase activity at downstream S regions during class-switch recombination.Regulation of immunoglobulin class-switch recombination: choreography of noncoding transcription, targeted DNA deamination, and long-range DNA repair.WRAD: enabler of the SET1-family of H3K4 methyltransferases.Roles for histone H3K4 methyltransferase activities during immunoglobulin class-switch recombinationActivation-induced cytidine deaminase targets DNA at sites of RNA polymerase II stalling by interaction with Spt5The DNA damage- and transcription-associated protein paxip1 controls thymocyte development and emigration.The AID-induced DNA damage response in chromatin.A phosphorylation switch on RbBP5 regulates histone H3 Lys4 methylation.The Groucho-associated phosphatase PPM1B displaces Pax transactivation domain interacting protein (PTIP) to switch the transcription factor Pax2 from a transcriptional activator to a repressor.Dynamic changes in binding of immunoglobulin heavy chain 3' regulatory region to protein factors during class switching.Mismatch-mediated error prone repair at the immunoglobulin genes.Immature B cells preferentially switch to IgE with increased direct Sμ to Sε recombination.The PTIP-Associated Histone Methyltransferase Complex Prevents Stress-Induced Maladaptive Cardiac Remodeling.Modulation of LSD1 phosphorylation by CK2/WIP1 regulates RNF168-dependent 53BP1 recruitment in response to DNA damageOrigin of immunoglobulin isotype switching.Mice lacking Sμ tandem repeats maintain RNA polymerase patterns but exhibit histone modification pattern shifts linked to class switch site locations.Iron inhibits activation-induced cytidine deaminase enzymatic activity and modulates immunoglobulin class switch DNA recombination.AIDing antibody diversity by error-prone mismatch repair.SCAI promotes DNA double-strand break repair in distinct chromosomal contextsA polyglutamine expansion disease protein sequesters PTIP to attenuate DNA repair and increase genomic instability.Three-dimensional architecture of the IgH locus facilitates class switch recombination.Immunoglobulin class-switch DNA recombination: induction, targeting and beyond.Epigenetics of the antibody responsePolyclonal hyper-IgE mouse model reveals mechanistic insights into antibody class switch recombinationInduction of activation-induced cytidine deaminase-targeting adaptor 14-3-3γ is mediated by NF-κB-dependent recruitment of CFP1 to the 5'-CpG-3'-rich 14-3-3γ promoter and is sustained by E2A.Combinatorial H3K9acS10ph histone modification in IgH locus S regions targets 14-3-3 adaptors and AID to specify antibody class-switch DNA recombination.PITX2 associates with PTIP-containing histone H3 lysine 4 methyltransferase complex.
P2860
Q24632504-0DF13A9A-B2AA-4CB4-8C8B-BC58B59DED4DQ26772330-92D7BA1C-7EA8-4A07-B08C-F5183F2B9D3BQ26781345-51BD54A0-3542-4903-89A4-99B343A91850Q26825793-3759B943-5996-415F-B891-91CAA423DD13Q26826949-6F0ED13A-7664-4BFD-82FD-D11EF6D2E43BQ27001131-CC7C477D-F1F0-435B-8C85-C34F289BBBF3Q27692655-D3AFFBCD-70BF-4EBB-A88F-F6DBB0B87CBCQ28000132-205E37DA-E54C-499A-AB09-B5BFCF9F7CBBQ28590053-09A8FDC8-6784-4167-A09D-EC396BF6692DQ28591850-1C0F066A-142E-4B00-9F17-8915A579DA5EQ30648765-67408128-225E-416A-A0FD-E74EF29ACE08Q33426259-A0F3E0D5-68B8-4A54-8E59-E1FE173B8398Q33690522-51E74F3A-A2E3-4406-BF82-E664D9B6C356Q33725435-34DFC2CD-B063-4843-8523-5537D25E0A28Q34115234-C4F9ED18-0574-4E05-9079-40ADE21B479CQ34278347-C51467A6-3894-46C0-A974-E43930BDA3B3Q34308191-D79701B5-BAC2-4BD2-B62D-4801F2A95F35Q34357060-CF1FE46E-0210-4736-B00A-3EF0C2E4C6BBQ34480227-5F076C9E-CC46-4910-83CF-5EEDF3C21B7AQ34715036-5BE1C791-062E-4247-ABE1-F1A8DF028C55Q34981623-9B129FA1-85A1-4290-87E3-76B77B6FE924Q35172685-D99137FD-4BBD-4EB6-83A6-C4C63F1035FAQ35310199-50D93296-EA0A-4C35-9077-3065301C9E43Q35605313-873768D9-FC13-416B-80DC-BEC4971A0E39Q35627706-02A53487-92E0-4EC5-81D0-90BE7CA049ABQ35639445-B1BEB174-5D6E-470D-B894-851ED8AA9D97Q35842531-7FB59A88-2927-456A-8A57-A7B24BFCEE42Q35989631-6E85D88E-8350-4FBF-A828-32AAC36B091BQ35992414-F349D8B6-32D1-4640-8612-916A184FBB9DQ36033318-007D6D33-B709-41AC-BFAD-39199E1FE208Q36173942-0A876A43-FAAF-43A9-8E88-C81C34F4B5C4Q36184268-CD2F9B46-2B55-4BF3-9A90-36797FBA220EQ36231685-AEEF686D-698A-42F6-8348-65262BC6305CQ36235676-DA7AFA99-A97A-42A9-A405-730C968C224AQ36534234-BD0BB9BA-1FE1-4DED-9D87-3A63369F8248Q37097751-FE71E098-4CE8-465E-AFB2-D2DED300C0B9Q37203980-0F427E4E-E724-45E5-BA3A-A649B21FD4CCQ37323207-01CC9DC5-320E-4EBD-AAE6-CA3B9FBBA64CQ37634047-BD461455-CC09-4FD0-8E87-57E7F1B20BFFQ37658191-8E332F17-0D35-4B8E-BBFB-76B379DC53E5
P2860
PTIP promotes chromatin changes critical for immunoglobulin class switch recombination
description
2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Science
@fr
artículu científicu espublizáu en 2010
@ast
im August 2010 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2010/08/20)
@sk
vědecký článek publikovaný v roce 2010
@cs
wetenschappelijk artikel (gepubliceerd op 2010/08/20)
@nl
наукова стаття, опублікована в серпні 2010
@uk
name
PTIP promotes chromatin changes critical for immunoglobulin class switch recombination
@ast
PTIP promotes chromatin changes critical for immunoglobulin class switch recombination
@en
PTIP promotes chromatin changes critical for immunoglobulin class switch recombination
@nl
type
label
PTIP promotes chromatin changes critical for immunoglobulin class switch recombination
@ast
PTIP promotes chromatin changes critical for immunoglobulin class switch recombination
@en
PTIP promotes chromatin changes critical for immunoglobulin class switch recombination
@nl
prefLabel
PTIP promotes chromatin changes critical for immunoglobulin class switch recombination
@ast
PTIP promotes chromatin changes critical for immunoglobulin class switch recombination
@en
PTIP promotes chromatin changes critical for immunoglobulin class switch recombination
@nl
P2093
P2860
P50
P356
P1433
P1476
PTIP promotes chromatin changes critical for immunoglobulin class switch recombination
@en
P2093
André Nussenzweig
Arito Yamane
Darius Filsuf
Gregory R. Dressler
Hong-Wei Sun
Hua-Tang Chen
Jeremy A. Daniel
Kristopher R. Schwab
Margarida Almeida Santos
P2860
P304
P356
10.1126/SCIENCE.1187942
P407
P577
2010-08-20T00:00:00Z