AIDing antibody diversity by error-prone mismatch repair.
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DNA triplet repeat expansion and mismatch repairRelated Mechanisms of Antibody Somatic Hypermutation and Class Switch RecombinationStructural, molecular and cellular functions of MSH2 and MSH6 during DNA mismatch repair, damage signaling and other noncanonical activitiesAID and Apobec3G haphazard deamination and mutational diversityEffects of prostaglandin E2 on p53 mRNA transcription and p53 mutagenesis during T-cell-independent human B-cell clonal expansionModels of somatic hypermutation targeting and substitution based on synonymous mutations from high-throughput immunoglobulin sequencing data.Generation and repair of AID-initiated DNA lesions in B lymphocytes.Binding of AID to DNA does not correlate with mutator activity.Refining the Neuberger model: Uracil processing by activated B cells.AID-initiated DNA lesions are differentially processed in distinct B cell populations.Overlapping hotspots in CDRs are critical sites for V region diversificationAberrant recombination and repair during immunoglobulin class switching in BRCA1-deficient human B cellsDNA mismatch repair: Dr. Jekyll and Mr. Hyde?Imbalanced PTEN and PI3K Signaling Impairs Class Switch Recombination.Combined deletion of Xrcc4 and Trp53 in mouse germinal center B cells leads to novel B cell lymphomas with clonal heterogeneityAntibody diversification caused by disrupted mismatch repair and promiscuous DNA polymerasesNon-canonical actions of mismatch repairMouse models of DNA mismatch repair in cancer research.Interplay between Target Sequences and Repair Pathways Determines Distinct Outcomes of AID-Initiated LesionsAID hits the jackpot when missing the target.Genomic Architecture may Influence Recurrent Chromosomal Translocation Frequency in the Igh Locus.Impaired B lymphopoiesis in old age: a role for inflammatory B cells?The dual nature of mismatch repair as antimutator and mutator: for better or for worse.Sequence-Intrinsic Mechanisms that Target AID Mutational Outcomes on Antibody GenesAntibody-specific model of amino acid substitution for immunological inferences from alignments of antibody sequences.The Complex Interplay between DNA Injury and Repair in Enzymatically Induced Mutagenesis and DNA Damage in B Lymphocytes.PTEN-Regulated AID Transcription in Germinal Center B Cells Is Essential for the Class-Switch Recombination and IgG Antibody Responses.Epigenomic Modifications Mediating Antibody Maturation.Transient AID expression for in situ mutagenesis with improved cellular fitness.Local Clonal Diversification and Dissemination of B Lymphocytes in the Human Bronchial MucosaThe Transcriptional Regulation of Germinal Center Formation
P2860
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P2860
AIDing antibody diversity by error-prone mismatch repair.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
AIDing antibody diversity by error-prone mismatch repair.
@ast
AIDing antibody diversity by error-prone mismatch repair.
@en
type
label
AIDing antibody diversity by error-prone mismatch repair.
@ast
AIDing antibody diversity by error-prone mismatch repair.
@en
prefLabel
AIDing antibody diversity by error-prone mismatch repair.
@ast
AIDing antibody diversity by error-prone mismatch repair.
@en
P2860
P1476
AIDing antibody diversity by error-prone mismatch repair.
@en
P2093
Matthew D Scharff
Winfried Edelmann
P2860
P304
P356
10.1016/J.SMIM.2012.05.005
P577
2012-06-14T00:00:00Z