Activin type IIA and IIB receptors mediate Gdf11 signaling in axial vertebral patterning
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Epithelial and ectomesenchymal role of the type I TGF-beta receptor ALK5 during facial morphogenesis and palatal fusionVACTERL/caudal regression/Currarino syndrome-like malformations in mice with mutation in the proprotein convertase Pcsk5Both WFIKKN1 and WFIKKN2 have high affinity for growth and differentiation factors 8 and 11Differential antagonism of activin, myostatin and growth and differentiation factor 11 by wild-type and mutant follistatinGrowth differentiation factor 11 signals through the transforming growth factor-beta receptor ALK5 to regionalize the anterior-posterior axisConditional expression of Smad7 in pancreatic beta cells disrupts TGF-beta signaling and induces reversible diabetes mellitusA Tale from TGF-β Superfamily for Thymus Ontogeny and Functionβ-thalassemias: paradigmatic diseases for scientific discoveries and development of innovative therapiesGDF11 Increases with Age and Inhibits Skeletal Muscle RegenerationB-cell translocation gene 2 (Btg2) regulates vertebral patterning by modulating bone morphogenetic protein/smad signalingDefective ALK5 signaling in the neural crest leads to increased postmigratory neural crest cell apoptosis and severe outflow tract defectsALK7, a receptor for nodal, is dispensable for embryogenesis and left-right patterning in the mouseTgif1 and Tgif2 Regulate Axial Patterning in Mouse.Gdf11 facilitates temporal progression of neurogenesis in the developing spinal cordMuscular atrophy of caveolin-3-deficient mice is rescued by myostatin inhibition.Highly sensitive and specific bioassay for measuring bioactive TGF-betaDicer is required for maintaining adult pancreas.Redundancy of myostatin and growth/differentiation factor 11 functionOvalbumin sensitization and challenge increases the number of lung cells possessing a mesenchymal stromal cell phenotypeA phase 1 study of ACE-536, a regulator of erythroid differentiation, in healthy volunteers.Activation of the growth-differentiation factor 11 gene by the histone deacetylase (HDAC) inhibitor trichostatin A and repression by HDAC3.METABOLIC FUNCTIONS OF MYOSTATIN AND GDF11.Identification and functional characterization of NODAL rare variants in heterotaxy and isolated cardiovascular malformations.Activin and GDF11 collaborate in feedback control of neuroepithelial stem cell proliferation and fate.Latent transforming growth factor beta-binding proteins-2 and -3 inhibit the proprotein convertase 5/6A.Bioluminescence imaging of Smad signaling in living mice shows correlation with excitotoxic neurodegeneration.The Inhibitory Core of the Myostatin Prodomain: Its Interaction with Both Type I and II Membrane Receptors, and Potential to Treat Muscle Atrophy.A study of vertebra number in pigs confirms the association of vertnin and reveals additional QTL.Developmental Patterning as a Quantitative Trait: Genetic Modulation of the Hoxb6 Mutant Skeletal Phenotype.The elusive philosopher's stone in young blood.In vivo functions of the proprotein convertase PC5/6 during mouse development: Gdf11 is a likely substrate.TGF-beta type I receptor Alk5 regulates tooth initiation and mandible patterning in a type II receptor-independent mannerMicroRNAs in Human Placental Development and Pregnancy Complications.Functional redundancy of type II BMP receptor and type IIB activin receptor in BMP2-induced osteoblast differentiationFras1, a basement membrane-associated protein mutated in Fraser syndrome, mediates both the initiation of the mammalian kidney and the integrity of renal glomeruli.On the origin of the beta cell.GDF11 decreases bone mass by stimulating osteoclastogenesis and inhibiting osteoblast differentiation.Establishment of Hox vertebral identities in the embryonic spine precursorsPancreas cell fate.TGF-β and the TGF-β Family: Context-Dependent Roles in Cell and Tissue Physiology.
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P2860
Activin type IIA and IIB receptors mediate Gdf11 signaling in axial vertebral patterning
description
2002 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2002
@ast
im November 2002 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2002/11/01)
@sk
vědecký článek publikovaný v roce 2002
@cs
wetenschappelijk artikel (gepubliceerd op 2002/11/01)
@nl
наукова стаття, опублікована в листопаді 2002
@uk
مقالة علمية (نشرت في نوفمبر 2002)
@ar
name
Activin type IIA and IIB receptors mediate Gdf11 signaling in axial vertebral patterning
@ast
Activin type IIA and IIB receptors mediate Gdf11 signaling in axial vertebral patterning
@en
Activin type IIA and IIB receptors mediate Gdf11 signaling in axial vertebral patterning
@nl
type
label
Activin type IIA and IIB receptors mediate Gdf11 signaling in axial vertebral patterning
@ast
Activin type IIA and IIB receptors mediate Gdf11 signaling in axial vertebral patterning
@en
Activin type IIA and IIB receptors mediate Gdf11 signaling in axial vertebral patterning
@nl
prefLabel
Activin type IIA and IIB receptors mediate Gdf11 signaling in axial vertebral patterning
@ast
Activin type IIA and IIB receptors mediate Gdf11 signaling in axial vertebral patterning
@en
Activin type IIA and IIB receptors mediate Gdf11 signaling in axial vertebral patterning
@nl
P2093
P2860
P3181
P356
P1433
P1476
Activin type IIA and IIB receptors mediate Gdf11 signaling in axial vertebral patterning
@en
P2093
Chang-Yeol Yeo
Heindrich Schrewe
Malcolm Whitman
S. Paul Oh
Youngjae Lee
P2860
P304
P3181
P356
10.1101/GAD.1021802
P577
2002-11-01T00:00:00Z