The orphan receptor ALK7 and the Activin receptor ALK4 mediate signaling by Nodal proteins during vertebrate development - Wikidata - awgldk - TriplyDB

The orphan receptor ALK7 and the Activin receptor ALK4 mediate signaling by Nodal proteins during vertebrate development

The orphan receptor ALK7 and the Activin receptor ALK4 mediate signaling by Nodal proteins during vertebrate development

http://www.wikidata.org/entity/Q24600802

about

Cripto: a tumor growth factor and more Cripto-1 activates nodal- and ALK4-dependent and -independent signaling pathways in mammary epithelial Cells Nodal and ALK7 inhibit proliferation and induce apoptosis in human trophoblast cells Nodal signals through activin receptor-like kinase 7 to inhibit trophoblast migration and invasion: implication in the pathogenesis of preeclampsia Myostatin signals through a transforming growth factor beta-like signaling pathway to block adipogenesis Dual roles of Cripto as a ligand and coreceptor in the nodal signaling pathway.Nodal enhances the activity of FoxO3a and its synergistic interaction with Smads to regulate cyclin G2 transcription in ovarian cancer cells Reactivation of embryonic nodal signaling is associated with tumor progression and promotes the growth of prostate cancer cells Endogenous TGF-beta signaling suppresses maturation of osteoblastic mesenchymal cells Identification of receptors and signaling pathways for orphan bone morphogenetic protein/growth differentiation factor ligands based on genomic analyses Activin receptor-like kinase-7 induces apoptosis through activation of MAPKs in a Smad3-dependent mechanism in hepatoma cells TGF-β control of stem cell differentiation genes Emerging roles of nodal and Cripto-1: from embryogenesis to breast cancer progression Nodal morphogens Cyclin G2 is degraded through the ubiquitin-proteasome pathway and mediates the antiproliferative effect of activin receptor-like kinase 7 Growth/differentiation factor 3 signals through ALK7 and regulates accumulation of adipose tissue and diet-induced obesity Cripto recruits Furin and PACE4 and controls Nodal trafficking during proteolytic maturation Activin controls skin morphogenesis and wound repair predominantly via stromal cells and in a concentration-dependent manner via keratinocytes Growth differentiation factor 11 signals through the transforming growth factor-beta receptor ALK5 to regionalize the anterior-posterior axis Lefty blocks a subset of TGFbeta signals by antagonizing EGF-CFC coreceptors Human Cerberus prevents nodal-receptor binding, inhibits nodal signaling, and suppresses nodal-mediated phenotypes A Poised Chromatin Platform for TGF-β Access to Master Regulators Activin receptor-like kinases: a diverse family playing an important role in cancer Identification of novel isoforms of activin receptor-like kinase 7 (ALK7) generated by alternative splicing and expression of ALK7 and its ligand, Nodal, in human placenta Establishment of vertebrate left-right asymmetry Whole-genome microRNA screening identifies let-7 and mir-18 as regulators of germ layer formation during early embryogenesis The role of a Williams-Beuren syndrome-associated helix-loop-helix domain-containing transcription factor in activin/nodal signaling ALK7, a receptor for nodal, is dispensable for embryogenesis and left-right patterning in the mouse Activin B receptor ALK7 is a negative regulator of pancreatic beta-cell function Activin-A and Bmp4 levels modulate cell type specification during CHIR-induced cardiomyogenesis Activin type IIA and IIB receptors mediate Gdf11 signaling in axial vertebral patterning Extracellular interactions and ligand degradation shape the nodal morphogen gradient Uterine Activin-Like Kinase 4 Regulates Trophoblast Development During Mouse Placentation.Regulation of extra-embryonic endoderm stem cell differentiation by Nodal and Cripto signaling Highly sensitive and specific bioassay for measuring bioactive TGF-beta Time-dependent patterning of the mesoderm and endoderm by Nodal signals in zebrafish Rasl11b knock down in zebrafish suppresses one-eyed-pinhead mutant phenotype.Riding shotgun: a dual role for the epidermal growth factor-Cripto/FRL-1/Cryptic protein Cripto in Nodal trafficking.Graded Nodal/Activin signaling titrates conversion of quantitative phospho-Smad2 levels into qualitative embryonic stem cell fate decisions.Adipocyte ALK7 links nutrient overload to catecholamine resistance in obesity

P2860

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P2860

The orphan receptor ALK7 and the Activin receptor ALK4 mediate signaling by Nodal proteins during vertebrate development

http://www.wikidata.org/entity/Q24600802

description

2001 nî lūn-bûn

@nan

2001 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2001 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2001年の論文

@ja

2001年論文

@yue

2001年論文

@zh-hant

2001年論文

@zh-hk

2001年論文

@zh-mo

2001年論文

@zh-tw

2001年论文

@wuu

name

The orphan receptor ALK7 and t ...... during vertebrate development

@ast

The orphan receptor ALK7 and t ...... during vertebrate development

@en

The orphan receptor ALK7 and t ...... during vertebrate development

@nl

type

label

The orphan receptor ALK7 and t ...... during vertebrate development

@ast

The orphan receptor ALK7 and t ...... during vertebrate development

@en

The orphan receptor ALK7 and t ...... during vertebrate development

@nl

prefLabel

The orphan receptor ALK7 and t ...... during vertebrate development

@ast

The orphan receptor ALK7 and t ...... during vertebrate development

@en

The orphan receptor ALK7 and t ...... during vertebrate development

@nl

P1433

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P2860

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Genes & Development

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The orphan receptor ALK7 and t ...... during vertebrate development

@en

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A Blokzijl

http://www.w3.org/2001/XMLSchema#string

A H Brivanlou

http://www.w3.org/2001/XMLSchema#string

C Chang

http://www.w3.org/2001/XMLSchema#string

C F Ibáñez

http://www.w3.org/2001/XMLSchema#string

E Reissmann

http://www.w3.org/2001/XMLSchema#string

G Minchiotti

http://www.w3.org/2001/XMLSchema#string

H Jörnvall

http://www.w3.org/2001/XMLSchema#string

M G Persico

http://www.w3.org/2001/XMLSchema#string

O Andersson

http://www.w3.org/2001/XMLSchema#string

P2860

TGF-beta signal transduction

Xenopus chordin: a novel dorsalizing factor activated by organizer-specific homeobox genes

The head inducer Cerberus is a multifunctional antagonist of Nodal, BMP and Wnt signals

Rapid and efficient site-specific mutagenesis without phenotypic selection

Xenopus GDF6, a new antagonist of noggin and a partner of BMPs

A primary requirement for nodal in the formation and maintenance of the primitive streak in the mouse

Nodal is a novel TGF-beta-like gene expressed in the mouse node during gastrulation

Cripto is required for correct orientation of the anterior-posterior axis in the mouse embryo

The orphan receptor serine/threonine kinase ALK7 signals arrest of proliferation and morphological differentiation in a neuronal cell line

Molecular cloning of a novel type I receptor serine/threonine kinase for the TGF beta superfamily from rat brain

P304

2010-22

http://www.w3.org/2001/XMLSchema#string

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scholarly article

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2170917

http://www.w3.org/2001/XMLSchema#string

P356

10.1101/GAD.201801

http://www.w3.org/2001/XMLSchema#string

P407

P433

15

http://www.w3.org/2001/XMLSchema#string

P478

15

http://www.w3.org/2001/XMLSchema#string

P577

2001-08-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

11857159

http://www.w3.org/2001/XMLSchema#string

P698

11485994

http://www.w3.org/2001/XMLSchema#string

P932

312747

http://www.w3.org/2001/XMLSchema#string