The type I activin receptor ActRIB is required for egg cylinder organization and gastrulation in the mouse
about
Identification of a functional binding site for activin on the type I receptor ALK4Hgs (Hrs), a FYVE domain protein, is involved in Smad signaling through cooperation with SARA.The orphan receptor ALK7 and the Activin receptor ALK4 mediate signaling by Nodal proteins during vertebrate developmentAsymmetric and node-specific nodal expression patterns are controlled by two distinct cis-acting regulatory elementsGrowth/differentiation factor 3 signals through ALK7 and regulates accumulation of adipose tissue and diet-induced obesityGrowth differentiation factor 11 signals through the transforming growth factor-beta receptor ALK5 to regionalize the anterior-posterior axisDifferential response of epiblast stem cells to Nodal and Activin signalling: a paradigm of early endoderm development in the embryoActivin receptor-like kinases: a diverse family playing an important role in cancerTGF-β family signaling in stem cellsThe transcription factor FoxH1 (FAST) mediates Nodal signaling during anterior-posterior patterning and node formation in the mouseFoxH1 (Fast) functions to specify the anterior primitive streak in the mouseRequirement for beta-catenin in anterior-posterior axis formation in miceALK7, a receptor for nodal, is dispensable for embryogenesis and left-right patterning in the mouseConserved requirement for EGF-CFC genes in vertebrate left-right axis formationUterine Activin-Like Kinase 4 Regulates Trophoblast Development During Mouse Placentation.Overexpression of follistatin in the mouse epididymis disrupts fluid resorption and sperm transit in testicular excurrent ductsGRP94 is essential for mesoderm induction and muscle development because it regulates insulin-like growth factor secretion.Arkadia enhances Nodal/TGF-beta signaling by coupling phospho-Smad2/3 activity and turnover.Regionalization of the mouse visceral endoderm as the blastocyst transforms into the egg cylinder.Differentiating embryonic stem cells pass through 'temporal windows' that mark responsiveness to exogenous and paracrine mesendoderm inducing signals.Homozygous deletion of the activin A receptor, type IB gene is associated with an aggressive cancer phenotype in pancreatic cancerConditional activin receptor type 1B (Acvr1b) knockout mice reveal hair loss abnormality.Nodal signalling in vertebrate development.Anterior visceral endoderm SMAD4 signaling specifies anterior embryonic patterning and head induction in mice.Inhibin at 90: from discovery to clinical application, a historical reviewActivin/Nodal signalling before implantation: setting the stage for embryo patterning.Roles of nodal-lefty regulatory loops in embryonic patterning of vertebrates.Mouse Tenm4 is required for mesoderm induction.Cripto forms a complex with activin and type II activin receptors and can block activin signalingThe topographical regulation of embryonic stem cell differentiationHepatocyte growth factor-regulated tyrosine kinase substrate (Hgs) is involved in BMP signaling through phosphorylation of SMADS and TAK1 in early mouse embryoFailure of egg cylinder elongation and mesoderm induction in mouse embryos lacking the tumor suppressor smad2.Cripto promotes A-P axis specification independently of its stimulatory effect on Nodal autoinduction.Postgastrulation Smad2-deficient embryos show defects in embryo turning and anterior morphogenesis.An en masse phenotype and function prediction system for Mus musculusCripto/GRP78 modulation of the TGF-β pathway in development and oncogenesisChallenges and advances in mouse modeling for human pancreatic tumorigenesis and metastasisDevelopmental plasticity, cell fate specification and morphogenesis in the early mouse embryo.Heading forwards: anterior visceral endoderm migration in patterning the mouse embryo.Activins and Inhibins: Roles in Development, Physiology, and Disease.
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P2860
The type I activin receptor ActRIB is required for egg cylinder organization and gastrulation in the mouse
description
1998 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի մարտին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1998
@ast
im März 1998 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1998/03/15)
@sk
vědecký článek publikovaný v roce 1998
@cs
wetenschappelijk artikel (gepubliceerd op 1998/03/15)
@nl
наукова стаття, опублікована в березні 1998
@uk
مقالة علمية (نشرت في 15-3-1998)
@ar
name
The type I activin receptor Ac ...... and gastrulation in the mouse
@ast
The type I activin receptor Ac ...... and gastrulation in the mouse
@en
The type I activin receptor Ac ...... and gastrulation in the mouse
@nl
type
label
The type I activin receptor Ac ...... and gastrulation in the mouse
@ast
The type I activin receptor Ac ...... and gastrulation in the mouse
@en
The type I activin receptor Ac ...... and gastrulation in the mouse
@nl
prefLabel
The type I activin receptor Ac ...... and gastrulation in the mouse
@ast
The type I activin receptor Ac ...... and gastrulation in the mouse
@en
The type I activin receptor Ac ...... and gastrulation in the mouse
@nl
P2093
P2860
P3181
P356
P1433
P1476
The type I activin receptor Ac ...... and gastrulation in the mouse
@en
P2093
B. B. Simpson
J. van den Eijnden-van Raaij
P. K. Donahoe
P2860
P304
P3181
P356
10.1101/GAD.12.6.844
P577
1998-03-15T00:00:00Z