Implication of the proprotein convertase NARC-1/PCSK9 in the development of the nervous system
about
The proprotein convertase PCSK9 induces the degradation of low density lipoprotein receptor (LDLR) and its closest family members VLDLR and ApoER2Self-association of human PCSK9 correlates with its LDLR-degrading activityMolecular biology of PCSK9: its role in LDL metabolismPCSK9 regulates neuronal apoptosis by adjusting ApoER2 levels and signalingEvidence for positive selection in the C-terminal domain of the cholesterol metabolism gene PCSK9 based on phylogenetic analysis in 14 primate speciesMolecular population genetics of PCSK9: a signature of recent positive selection.Abnormal gene expression in cerebellum of Npc1-/- mice during postnatal development.Molecular and cellular function of the proprotein convertase subtilisin/kexin type 9 (PCSK9).Biology of proprotein convertase subtilisin kexin 9: beyond low-density lipoprotein cholesterol lowering.PCSK9 reduces the protein levels of the LDL receptor in mouse brain during development and after ischemic stroke.PCSK9 regulates apoptosis in human neuroglioma u251 cells via mitochondrial signaling pathways.Identification of PCSK9 as a novel serum biomarker for the prenatal diagnosis of neural tube defects using iTRAQ quantitative proteomics.Serum proprotein convertase subtilisin/kexin type 9 and cell surface low-density lipoprotein receptor: evidence for a reciprocal regulation.Mutations and polymorphisms in the proprotein convertase subtilisin kexin 9 (PCSK9) gene in cholesterol metabolism and disease.Proprotein convertase subtilisin/kexin type 7 (PCSK7) is essential for the zebrafish development and bioavailability of transforming growth factor β1a (TGFβ1a).The dual behavior of PCSK9 in the regulation of apoptosis is crucial in Alzheimer's disease progression (Review).Zebrafish models of dyslipidemia: relevance to atherosclerosis and angiogenesis.PCSK9 Inhibitors: potential in cardiovascular therapeutics.Using Human 'Experiments of Nature' to Predict Drug Safety Issues: An Example with PCSK9 Inhibitors.Methylomic profiling and replication implicates deregulation of PCSK9 in alcohol use disorder.Molecular changes associated with hippocampal long-lasting depression induced by the serine protease subtilisin-A.
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P2860
Implication of the proprotein convertase NARC-1/PCSK9 in the development of the nervous system
description
2006 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2006
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scientific journal article
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vedecký článok (publikovaný 2006/08/01)
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vědecký článek publikovaný v roce 2006
@cs
wetenschappelijk artikel (gepubliceerd op 2006/08/01)
@nl
наукова стаття, опублікована в серпні 2006
@uk
مقالة علمية (نشرت في أغسطس 2006)
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name
Implication of the proprotein ...... elopment of the nervous system
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Implication of the proprotein ...... elopment of the nervous system
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Implication of the proprotein ...... elopment of the nervous system
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type
label
Implication of the proprotein ...... elopment of the nervous system
@ast
Implication of the proprotein ...... elopment of the nervous system
@en
Implication of the proprotein ...... elopment of the nervous system
@nl
prefLabel
Implication of the proprotein ...... elopment of the nervous system
@ast
Implication of the proprotein ...... elopment of the nervous system
@en
Implication of the proprotein ...... elopment of the nervous system
@nl
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P2860
P50
P1476
Implication of the proprotein ...... elopment of the nervous system
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P2093
Babykumari P Chitramuthu
Benoit Cadieux
Edwige Marcinkiewicz
Hugh P J Bennett
Joanne Paquin
Steve Poirier
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P304
P356
10.1111/J.1471-4159.2006.03928.X
P407
P577
2006-08-01T00:00:00Z