Decreased lipid synthesis in livers of mice with disrupted Site-1 protease gene
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Overexpression of ABCG5 and ABCG8 promotes biliary cholesterol secretion and reduces fractional absorption of dietary cholesterolLiver X receptors in the central nervous system: from lipid homeostasis to neuronal degenerationLiver-specific mRNA for Insig-2 down-regulated by insulin: implications for fatty acid synthesisOverexpression of Insig-1 in the livers of transgenic mice inhibits SREBP processing and reduces insulin-stimulated lipogenesisCholesterol feedback: from Schoenheimer's bottle to Scap's MELADLThe rat STSL locus: characterization, chromosomal assignment, and genetic variations in sitosterolemic hypertensive ratsA mouse model of sitosterolemia: absence of Abcg8/sterolin-2 results in failure to secrete biliary cholesterolInsights into the molecular mechanisms of the anti-atherogenic actions of flavonoids in normal and obese miceIncreased cholesterol biosynthesis and hypercholesterolemia in mice overexpressing squalene synthase in the liverABCG5 and ABCG8 require MDR2 for secretion of cholesterol into bileSchoenheimer effect explained--feedback regulation of cholesterol synthesis in mice mediated by Insig proteinsDecreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9Maintaining cholesterol homeostasis: sterol regulatory element-binding proteinsSREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liverThe multifaceted proprotein convertases: their unique, redundant, complementary, and opposite functionsA rapid fluorometric assay for the proteolytic activity of SKI-1/S1P based on the surface glycoprotein of the hemorrhagic fever Lassa virus.LXR-SREBP-1c-phospholipid transfer protein axis controls very low density lipoprotein (VLDL) particle sizeSite-1 protease is required for cartilage development in zebrafish.Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1cObesity resistant mechanisms in the Lean polygenic mouse model as indicated by liver transcriptome and expression of selected genes in skeletal muscle.Ghrelin O-acyltransferase (GOAT) is essential for growth hormone-mediated survival of calorie-restricted mice.Cartilage-specific ablation of site-1 protease in mice results in the endoplasmic reticulum entrapment of type IIb procollagen and down-regulation of cholesterol and lipid homeostasis.Dietary cholesterol reverses resistance to diet-induced weight gain in mice lacking Niemann-Pick C1-Like 1.What lies ahead for the proprotein convertases?Niemann-Pick C1-Like 1 deletion in mice prevents high-fat diet-induced fatty liver by reducing lipogenesis.Deletion of the gene encoding proprotein convertase 5/6 causes early embryonic lethality in the mouseMarginal maternal biotin deficiency in CD-1 mice reduces fetal mass of biotin-dependent carboxylasesDisruption of Abcg5 and Abcg8 in mice reveals their crucial role in biliary cholesterol secretion.Deletion of ELOVL6 blocks the synthesis of oleic acid but does not prevent the development of fatty liver or insulin resistance.Hypomorphic mutation in the site-1 protease Mbtps1 endows resistance to persistent viral infection in a cell-specific manner.New perspectives in the regulation of hepatic glycolytic and lipogenic genes by insulin and glucose: a role for the transcription factor sterol regulatory element binding protein-1c.Liver-specific deletion of acetyl-CoA carboxylase 1 reduces hepatic triglyceride accumulation without affecting glucose homeostasisSite-1 protease is essential to growth plate maintenance and is a critical regulator of chondrocyte hypertrophic differentiation in postnatal miceEarly growth response 1 (Egr1) regulates cholesterol biosynthetic gene expression.Muscle-specific deletion of comparative gene identification-58 (CGI-58) causes muscle steatosis but improves insulin sensitivity in male mice.MBTPS1/SKI-1/S1P proprotein convertase is required for ECM signaling and axial elongation during somitogenesis and vertebral development†.Biomineralization of bone: a fresh view of the roles of non-collagenous proteins.FOXO1 increases CCL20 to promote NF-κB-dependent lymphocyte chemotaxisApolipoprotein A-IV regulates chylomicron metabolism-mechanism and function.Hypopigmentation and maternal-zygotic embryonic lethality caused by a hypomorphic mbtps1 mutation in mice
P2860
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P2860
Decreased lipid synthesis in livers of mice with disrupted Site-1 protease gene
description
2001 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 2001
@ast
im November 2001 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2001/11/20)
@sk
vědecký článek publikovaný v roce 2001
@cs
wetenschappelijk artikel (gepubliceerd op 2001/11/20)
@nl
наукова стаття, опублікована в листопаді 2001
@uk
name
Decreased lipid synthesis in livers of mice with disrupted Site-1 protease gene
@ast
Decreased lipid synthesis in livers of mice with disrupted Site-1 protease gene
@en
Decreased lipid synthesis in livers of mice with disrupted Site-1 protease gene
@nl
type
label
Decreased lipid synthesis in livers of mice with disrupted Site-1 protease gene
@ast
Decreased lipid synthesis in livers of mice with disrupted Site-1 protease gene
@en
Decreased lipid synthesis in livers of mice with disrupted Site-1 protease gene
@nl
prefLabel
Decreased lipid synthesis in livers of mice with disrupted Site-1 protease gene
@ast
Decreased lipid synthesis in livers of mice with disrupted Site-1 protease gene
@en
Decreased lipid synthesis in livers of mice with disrupted Site-1 protease gene
@nl
P2093
P2860
P3181
P356
P1476
Decreased lipid synthesis in livers of mice with disrupted Site-1 protease gene
@en
P2093
J. D. Horton
J. L. Goldstein
M. S. Brown
R. E. Hammer
Y. A. Moon
P2860
P304
13607–13612
P3181
P356
10.1073/PNAS.201524598
P407
P577
2001-11-20T00:00:00Z