Characterization of STEF, a guanine nucleotide exchange factor for Rac1, required for neurite growth
about
The PHCCEx domain of Tiam1/2 is a novel protein- and membrane-binding moduleEct2 and MgcRacGAP regulate the activation and function of Cdc42 in mitosisThe Rac GTP exchange factor TIAM-1 acts with CDC-42 and the guidance receptor UNC-40/DCC in neuronal protrusion and axon guidanceTrkB binds and tyrosine-phosphorylates Tiam1, leading to activation of Rac1 and induction of changes in cellular morphologyTiam1 mediates neurite outgrowth induced by ephrin-B1 and EphA2SCLIP, a microtubule-destabilizing factor, interacts with RasGRF1 and inhibits its ability to promote Rac activation and neurite outgrowthRas activation of a Rac1 exchange factor, Tiam1, mediates neurotrophin-3-induced Schwann cell migrationPhosphorylation of STEF/Tiam2 by protein kinase A is critical for Rac1 activation and neurite outgrowth in dibutyryl cAMP-treated PC12D cellsRedox modifier genes and pathways in amyotrophic lateral sclerosis.Distinct ligand specificity of the Tiam1 and Tiam2 PDZ domainsCoupling neurotrophins to cell migration through selective guanine nucleotide exchange factor activationStructural and thermodynamic analysis of PDZ-ligand interactions.The role of Rho GTPase proteins in CNS neuronal migration.The in vivo roles of STEF/Tiam1, Rac1 and JNK in cortical neuronal migrationGuanine nucleotide exchange factor αPIX leads to activation of the Rac 1 GTPase/glycogen phosphorylase pathway in interleukin (IL)-2-stimulated T cells.Kalirin: a dual Rho guanine nucleotide exchange factor that is so much more than the sum of its many parts.Insulin receptor signaling in the development of neuronal structure and function.Rho-guanine nucleotide exchange factors during development: Force is nothing without control.Balanced Vav2 GEF activity regulates neurite outgrowth and branching in vitro and in vivoTara up-regulates E-cadherin transcription by binding to the Trio RhoGEF and inhibiting Rac signaling.Expression of T-cell lymphoma invasion and metastasis 2 (TIAM2) promotes proliferation and invasion of liver cancer.Requirement of ZO-1 for the formation of belt-like adherens junctions during epithelial cell polarization.A CDC42-centered signaling unit is a dominant positive regulator of endothelial integrity.PAR-6-PAR-3 mediates Cdc42-induced Rac activation through the Rac GEFs STEF/Tiam1.ROCK and mDia1 antagonize in Rho-dependent Rac activation in Swiss 3T3 fibroblasts.Crystallographic characterization of the membrane-targeting domains of the Rac-specific guanine nucleotide-exchange factors Tiam1 and Tiam2P-Rex2, a Rac-guanine nucleotide exchange factor, is expressed selectively in ribbon synaptic terminals of the mouse retina.Epac signaling pathway involves STEF, a guanine nucleotide exchange factor for Rac, to regulate APP processing.Rufy3 is an adapter protein for small GTPases that activates a Rac guanine nucleotide exchange factor to control neuronal polarity.Rac is a dominant regulator of cadherin-directed actin assembly that is activated by adhesive ligation independently of Tiam1.Intracellular cAMP Sensor EPAC: Physiology, Pathophysiology, and Therapeutics Development.
P2860
Q24314777-83818527-693D-4049-AA0E-8D0FCB94FDEFQ24337741-2E9B7B22-C7E1-4CEC-9C05-A8315605BD60Q27334152-B0161055-CDCE-4099-B0C0-40F2E94F9726Q28505203-9080DB64-1401-4ADF-8C16-A3A81B74D0B1Q28513624-28CB3ECF-0387-4059-A199-CC46D1496620Q28564467-0DE879EB-C263-407B-B9C3-AF9308A2C650Q28579777-6D78769A-CA00-4EC0-A232-F5962529C6DCQ30500214-4D654E68-CF9A-43DC-A5D5-00A8D1C4CDC4Q33742737-80999036-6547-478B-B528-5D9CE4990F66Q33782157-BFA27690-FFFC-4ED0-AF73-9149D7BFB661Q33937013-E8B6D6A3-EAC5-4674-B937-FF8A73FA2BEBQ34064336-CD30887F-6A3C-4740-A86B-2266C06A1925Q35281262-75FC9C16-5CA3-4671-901F-86BAC29B7B3EQ35561905-8641BEB6-EE23-486C-A043-2018FFA6219EQ35580883-34204789-C375-463E-AFEF-1FCACB0FE3F5Q36061166-12124B18-812E-4C67-AE8C-EBD559187FB2Q37709539-0014D84B-7155-4D15-97AF-92B1DEAF66CCQ37891679-C3486351-A32A-4A2B-BFD6-F3BEA949CD24Q38487501-01A8E03C-0085-4871-88BB-3557CDF1A0D5Q39560505-E0FBA18E-3F44-4B00-857E-E2317297F694Q39563462-E1C4FB5B-ECE7-4D97-98B1-A0CA42B9C612Q39734201-894DD5CF-EAD7-44C6-B789-67107F16564AQ40062087-3F8B4984-9C19-4CE2-B085-0A560E6A5D33Q40456149-6D4C0A48-88E6-41A3-ADAB-058C50B524C6Q41954269-A0730F78-3314-4C2B-9BE4-70D8B7635448Q42001048-6E4E97E5-2AD9-4926-A6DE-ED9794386410Q43084865-3204392B-C2B8-4970-877D-7B7448EA300BQ46874924-A6340D17-8906-47B7-A1B7-1DDB3A0E41AAQ47580998-6B7A4B48-E08C-48DC-B17F-EC3BFF9EB199Q51803381-333D20C2-4D15-49FA-8593-1D2711C2DE0EQ52656382-EC3AB85B-7CDF-456C-95A4-9403A705576F
P2860
Characterization of STEF, a guanine nucleotide exchange factor for Rac1, required for neurite growth
description
2002 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունվարին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2002
@ast
im Januar 2002 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2002/01/25)
@sk
vědecký článek publikovaný v roce 2002
@cs
wetenschappelijk artikel (gepubliceerd op 2002/01/25)
@nl
наукова стаття, опублікована в січні 2002
@uk
name
Characterization of STEF, a gu ...... 1, required for neurite growth
@ast
Characterization of STEF, a gu ...... 1, required for neurite growth
@en
Characterization of STEF, a gu ...... 1, required for neurite growth
@nl
type
label
Characterization of STEF, a gu ...... 1, required for neurite growth
@ast
Characterization of STEF, a gu ...... 1, required for neurite growth
@en
Characterization of STEF, a gu ...... 1, required for neurite growth
@nl
prefLabel
Characterization of STEF, a gu ...... 1, required for neurite growth
@ast
Characterization of STEF, a gu ...... 1, required for neurite growth
@en
Characterization of STEF, a gu ...... 1, required for neurite growth
@nl
P2860
P356
P1476
Characterization of STEF, a gu ...... 1, required for neurite growth
@en
P2093
Mikio Hoshino
Yo-ichi Nabeshima
P2860
P304
P356
10.1074/JBC.M106186200
P407
P577
2001-11-13T00:00:00Z