The Ikaros gene is required for the development of all lymphoid lineages
about
Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylationFunctions of E2A-HEB heterodimers in T-cell development revealed by a dominant negative mutation of HEBEos and pegasus, two members of the Ikaros family of proteins with distinct DNA binding activitiesThe human interferon-inducible protein, IFI 16, is a repressor of transcriptionRepression by Ikaros and Aiolos is mediated through histone deacetylase complexesExpression of dominant-negative and mutant isoforms of the antileukemic transcription factor Ikaros in infant acute lymphoblastic leukemiaZinc finger-mediated protein interactions modulate Ikaros activity, a molecular control of lymphocyte developmentHelios, a T cell-restricted Ikaros family member that quantitatively associates with Ikaros at centromeric heterochromatinRole of Ikaros in T-cell acute lymphoblastic leukemiaSecreted and membrane attractin result from alternative splicing of the human ATRN geneGenetic abnormalities associated with acute lymphoblastic leukemiaNovel agents and biomarkers for acute lymphoid leukemiaThe Interplay between Chromatin and Transcription Factor Networks during B Cell Development: Who Pulls the Trigger First?MicroRNAs in B cell development and malignancyCurrent concepts in pediatric Philadelphia chromosome-positive acute lymphoblastic leukemiaTLR7/9 versus TLR3/MDA5 signaling during virus infections and diabetesThe Ikaros family of zinc-finger proteinsCongenital pancytopenia and absence of B lymphocytes in a neonate with a mutation in the Ikaros geneHuman tumor necrosis factor receptor p75/80 (CD120b) gene structure and promoter characterizationIkaros interactions with CtBP reveal a repression mechanism that is independent of histone deacetylase activityEos: a novel member of the Ikaros gene family expressed predominantly in the developing nervous systemAML1 interconnected pathways of leukemogenesisIkaros gene expression and leukemiaIkaros-CtIP interactions do not require C-terminal binding protein and participate in a deacetylase-independent mode of repressionUnconventional potentiation of gene expression by IkarosVasoactive intestinal peptide receptor-1 (VPAC-1) is a novel gene target of the hemolymphopoietic transcription factor IkarosA molecular dissection of the repression circuitry of IkarosLoci on 7p12.2, 10q21.2 and 14q11.2 are associated with risk of childhood acute lymphoblastic leukemiaGenome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosusLenalidomide causes selective degradation of IKZF1 and IKZF3 in multiple myeloma cellsDown-regulation of TDT transcription in CD4(+)CD8(+) thymocytes by Ikaros proteins in direct competition with an Ets activatorMyh7b/miR-499 gene expression is transcriptionally regulated by MRFs and EosRegulation of lymphoid versus myeloid fate 'choice' by the transcription factor Mef2cBcl11a is essential for normal lymphoid developmentThe Ikaros gene encodes a family of functionally diverse zinc finger DNA-binding proteinsMolecular specification and patterning of progenitor cells in the lateral and medial ganglionic eminencesIsolation and characterization of a novel member of the neural zinc finger factor/myelin transcription factor family with transcriptional repression activityZBTB1 is a determinant of lymphoid developmentAn essential role for the hematopoietic transcription factor Ikaros in hypothalamic-pituitary-mediated somatic growth.Foxp1 is an essential transcriptional regulator of B cell development
P2860
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P2860
The Ikaros gene is required for the development of all lymphoid lineages
description
1994 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1994
@ast
im Oktober 1994 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1994/10/07)
@sk
vědecký článek publikovaný v roce 1994
@cs
wetenschappelijk artikel (gepubliceerd op 1994/10/07)
@nl
наукова стаття, опублікована в жовтні 1994
@uk
مقالة علمية (نشرت في 7-10-1994)
@ar
name
The Ikaros gene is required for the development of all lymphoid lineages
@ast
The Ikaros gene is required for the development of all lymphoid lineages
@en
The Ikaros gene is required for the development of all lymphoid lineages
@nl
type
label
The Ikaros gene is required for the development of all lymphoid lineages
@ast
The Ikaros gene is required for the development of all lymphoid lineages
@en
The Ikaros gene is required for the development of all lymphoid lineages
@nl
prefLabel
The Ikaros gene is required for the development of all lymphoid lineages
@ast
The Ikaros gene is required for the development of all lymphoid lineages
@en
The Ikaros gene is required for the development of all lymphoid lineages
@nl
P2093
P3181
P1433
P1476
The Ikaros gene is required for the development of all lymphoid lineages
@en
P2093
J. H. Wang
K. Georgopoulos
S. Winandy
P304
P3181
P356
10.1016/0092-8674(94)90407-3
P407
P577
1994-10-07T00:00:00Z