Investigation of the atypical FBXW7 mutation spectrum in human tumours by conditional expression of a heterozygous propellor tip missense allele in the mouse intestines

Investigation of the atypical FBXW7 mutation spectrum in human tumours by conditional expression of a heterozygous propellor tip missense allele in the mouse intestines

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http://www.wikidata.org/entity/Q28658581
Ubiquitin proteasome system research in gastrointestinal cancerFBW7-mediated ubiquitination and degradation of KLF5Deregulation of F-box proteins and its consequence on cancer development, progression and metastasis.FBXW7 missense mutation: a novel negative prognostic factor in metastatic colorectal adenocarcinoma.Tumor suppression by the Fbw7 ubiquitin ligase: mechanisms and opportunities.Roles of F-box proteins in cancerOncogenic mutations in the FBXW7 gene of adult T-cell leukemia patientsA colon cancer-derived mutant of Krüppel-like factor 5 (KLF5) is resistant to degradation by glycogen synthase kinase 3β (GSK3β) and the E3 ubiquitin ligase F-box and WD repeat domain-containing 7α (FBW7α).Distinct Interactions of EBP1 Isoforms with FBXW7 Elicits Different Functions in Cancer.FBXW7-mutated colorectal cancer cells exhibit aberrant expression of phosphorylated-p53 at Serine-15.Fbxw7-associated drug resistance is reversed by induction of terminal differentiation in murine intestinal organoid culture.Establishment and analysis of a novel mouse line carrying a conditional knockin allele of a cancer-specific FBXW7 mutation.The deubiquitinase USP9X regulates FBW7 stability and suppresses colorectal cancer.Functional significance and therapeutic implication of ring-type E3 ligases in colorectal cancer.Dysregulated Wnt signalling and recurrent mutations of the tumour suppressor RNF43 in early gastric carcinogenesis.
P2860

Investigation of the atypical FBXW7 mutation spectrum in human tumours by conditional expression of a heterozygous propellor tip missense allele in the mouse intestines

Item
http://www.wikidata.org/entity/Q28658581
description
2014 nî lūn-bûn
@nan
2014 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Investigation of the atypical ...... allele in the mouse intestines
@ast
Investigation of the atypical ...... allele in the mouse intestines
@en
Investigation of the atypical ...... allele in the mouse intestines
@nl
type
label
Investigation of the atypical ...... allele in the mouse intestines
@ast
Investigation of the atypical ...... allele in the mouse intestines
@en
Investigation of the atypical ...... allele in the mouse intestines
@nl
altLabel
Investigation of the atypicalF ...... allele in the mouse intestines
@en
prefLabel
Investigation of the atypical ...... allele in the mouse intestines
@ast
Investigation of the atypical ...... allele in the mouse intestines
@en
Investigation of the atypical ...... allele in the mouse intestines
@nl
P1433
P1476
P2093
P2860
P304
P31
P3181
P356
P407
P433
P478
P50
P577
P5875
P698
P932
P3181
P356
P1433
P1476
Investigation of the atypical ...... allele in the mouse intestines
@en
P2093
P2860
P304
P31
P3181
P356
10.1136/GUTJNL-2013-304719
P407
P433
P478
P50
P577
P5875
P698
P932