Akt deficiency attenuates muscle size and function but not the response to ActRIIB inhibition
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Connecting Myokines and MetabolismCellular and molecular mechanisms of muscle atrophySGK1: The Dark Side of PI3K Signaling.Disassociation of insulin action and Akt/FOXO signaling in skeletal muscle of older Akt-deficient mice.Differential muscle hypertrophy is associated with satellite cell numbers and Akt pathway activation following activin type IIB receptor inhibition in Mtm1 p.R69C miceTargeting the activin type IIB receptor to improve muscle mass and function in the mdx mouse model of Duchenne muscular dystrophy.Protein supplementation increases postexercise plasma myostatin concentration after 8 weeks of resistance training in young physically active subjectsEffect of postdevelopmental myostatin depletion on myofibrillar protein metabolism.Follistatin-mediated skeletal muscle hypertrophy is regulated by Smad3 and mTOR independently of myostatinRole of IGF-I in follistatin-induced skeletal muscle hypertrophy.Blockade of the activin receptor IIb activates functional brown adipogenesis and thermogenesis by inducing mitochondrial oxidative metabolismActivation of serum/glucocorticoid-induced kinase 1 (SGK1) is important to maintain skeletal muscle homeostasis and prevent atrophy.Temporal effects of ethanol consumption on energy homeostasis, hepatic steatosis, and insulin sensitivity in mice.Murine models of atrophy, cachexia, and sarcopenia in skeletal muscle.Sparing of the dystrophin-deficient cranial sartorius muscle is associated with classical and novel hypertrophy pathways in GRMD dogsAn antibody blocking activin type II receptors induces strong skeletal muscle hypertrophy and protects from atrophy.Local overexpression of the myostatin propeptide increases glucose transporter expression and enhances skeletal muscle glucose disposal.Denervation atrophy is independent from Akt and mTOR activation and is not rescued by myostatin inhibitionCharacterization and regulation of mechanical loading-induced compensatory muscle hypertrophy.The role of mouse Akt2 in insulin-dependent suppression of adipocyte lipolysis in vivoLoss of Akt1 in mice increases energy expenditure and protects against diet-induced obesity.Muscle protein synthesis, mTORC1/MAPK/Hippo signaling, and capillary density are altered by blocking of myostatin and activins.Transcriptional profiling and miRNA-dependent regulatory network analysis of longissimus dorsi muscle during prenatal and adult stages in two distinct pig breeds.Blockade of activin type II receptors with a dual anti-ActRIIA/IIB antibody is critical to promote maximal skeletal muscle hypertrophy.Fenofibrate prevents skeletal muscle loss in mice with lung cancer.Maintaining skeletal muscle mass: lessons learned from hibernation.The Exposure to Different Photoperiods Strongly Modulates the Glucose and Lipid Metabolisms of Normoweight Fischer 344 Rats.
P2860
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P2860
Akt deficiency attenuates muscle size and function but not the response to ActRIIB inhibition
description
2010 nî lūn-bûn
@nan
2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Akt deficiency attenuates musc ...... response to ActRIIB inhibition
@ast
Akt deficiency attenuates musc ...... response to ActRIIB inhibition
@en
Akt deficiency attenuates musc ...... response to ActRIIB inhibition
@nl
type
label
Akt deficiency attenuates musc ...... response to ActRIIB inhibition
@ast
Akt deficiency attenuates musc ...... response to ActRIIB inhibition
@en
Akt deficiency attenuates musc ...... response to ActRIIB inhibition
@nl
prefLabel
Akt deficiency attenuates musc ...... response to ActRIIB inhibition
@ast
Akt deficiency attenuates musc ...... response to ActRIIB inhibition
@en
Akt deficiency attenuates musc ...... response to ActRIIB inhibition
@nl
P2093
P2860
P1433
P1476
Akt deficiency attenuates musc ...... response to ActRIIB inhibition
@en
P2093
Anthony Balduzzi
Emidio E Pistilli
Jennifer Lachey
Rexford S Ahima
Tejvir S Khurana
P2860
P304
P356
10.1371/JOURNAL.PONE.0012707
P407
P577
2010-09-15T00:00:00Z