Sex, age, and regional differences in L-type calcium current are important determinants of arrhythmia phenotype in rabbit hearts with drug-induced long QT type 2
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Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Afford New Opportunities in Inherited Cardiovascular Disease ModelingSex differences in the mechanisms underlying long QT syndromeRapid multislice T1 mapping of mouse myocardium: Application to quantification of manganese uptake in α-Dystrobrevin knockout miceAcute effects of sex steroid hormones on susceptibility to cardiac arrhythmias: a simulation studyPopulation of computational rabbit-specific ventricular action potential models for investigating sources of variability in cellular repolarisationBradycardia alters Ca(2+) dynamics enhancing dispersion of repolarization and arrhythmia riskThe Electrogenic Na+/K+ Pump Is a Key Determinant of Repolarization Abnormality Susceptibility in Human Ventricular Cardiomyocytes: A Population-Based Simulation Study.Contributions of ion channel currents to ventricular action potential changes and induction of early afterdepolarizations during acute hypoxia.A multiscale computational modelling approach predicts mechanisms of female sex risk in the setting of arousal-induced arrhythmias.Robust anti-arrhythmic efficacy of verapamil and flunarizine against dofetilide-induced TdP arrhythmias is based upon a shared and a different mode of action.Deciphering Arrhythmia Mechanisms - Tools of the TradeModels of HERG gatingWITHDRAWN: Sex-differences in sodium/calcium exchange expression is a determinant of the arrhythmia phenotype in pre-pubertal rabbit hearts with Long QT type 2.How do sex hormones modify arrhythmogenesis in long QT syndrome? Sex hormone effects on arrhythmogenic substrate and triggered activity.Quantification of repolarization reserve to understand interpatient variability in the response to proarrhythmic drugs: a computational analysisSynchronous systolic subcellular Ca2+-elevations underlie ventricular arrhythmia in drug-induced long QT type 2.Ranolazine stabilizes cardiac ryanodine receptors: a novel mechanism for the suppression of early afterdepolarization and torsades de pointes in long QT type 2.Field and action potential recordings in heart slices: correlation with established in vitro and in vivo models.In silico Prediction of Sex-Based Differences in Human Susceptibility to Cardiac Ventricular TachyarrhythmiasComputational assessment of drug-induced effects on the electrocardiogram: from ion channel to body surface potentialsThe link between abnormal calcium handling and electrical instability in acquired long QT syndrome--Does calcium precipitate arrhythmic storms?Variability in cardiac electrophysiology: Using experimentally-calibrated populations of models to move beyond the single virtual physiological human paradigm.Increased late sodium current contributes to long QT-related arrhythmia susceptibility in female mice.Sex differences in mechanisms of cardiac excitation-contraction couplingVentricular arrhythmia risk after subarachnoid hemorrhage.Sensitivity of rabbit ventricular action potential and Ca²⁺ dynamics to small variations in membrane currents and ion diffusion coefficients.NCX is an important determinant for premature ventricular activity in a drug-induced model of Andersen-Tawil syndrome.Estrogen regulation of protein expression and signaling pathways in the heart.The systems biology approach to drug development: application to toxicity assessment of cardiac drugs.Phenotypical manifestations of mutations in the genes encoding subunits of the cardiac voltage-dependent L-type calcium channelSex-deparities in cardiac electrophysiology: L-type Ca2+ current and the Na+-Ca2+ exchanger go hand in hand.Sex differences in cardiac autonomic regulation and in repolarisation electrocardiography.Congenital long QT syndromes: prevalence, pathophysiology and management.Transmural gradients in ion channel and auxiliary subunit expression.Genomic upregulation of cardiac Cav1.2α and NCX1 by estrogen in women.Daurisoline suppressed early afterdepolarizations and inhibited L-type calcium current.Amylin and diabetic cardiomyopathy - amylin-induced sarcolemmal Ca2+ leak is independent of diabetic remodeling of myocardium.Spontaneous initiation of premature ventricular complexes and arrhythmias in type 2 long QT syndrome.Sex and regional differences in rabbit right ventricular L-type calcium current levels and mathematical modelling of arrhythmia vulnerability.The association of premature ovarian failure with ventricular repolarization dynamics evaluated by QT dynamicity.
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P2860
Sex, age, and regional differences in L-type calcium current are important determinants of arrhythmia phenotype in rabbit hearts with drug-induced long QT type 2
description
2008 nî lūn-bûn
@nan
2008 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Sex, age, and regional differe ...... th drug-induced long QT type 2
@ast
Sex, age, and regional differe ...... th drug-induced long QT type 2
@en
Sex, age, and regional differe ...... th drug-induced long QT type 2
@nl
type
label
Sex, age, and regional differe ...... th drug-induced long QT type 2
@ast
Sex, age, and regional differe ...... th drug-induced long QT type 2
@en
Sex, age, and regional differe ...... th drug-induced long QT type 2
@nl
prefLabel
Sex, age, and regional differe ...... th drug-induced long QT type 2
@ast
Sex, age, and regional differe ...... th drug-induced long QT type 2
@en
Sex, age, and regional differe ...... th drug-induced long QT type 2
@nl
P2093
P2860
P3181
P1433
P1476
Sex, age, and regional differe ...... th drug-induced long QT type 2
@en
P2093
Bum-Rak Choi
Guy Salama
Prakash C Viswanathan
Steven Reisenweber
William H Walker
P2860
P304
P3181
P356
10.1161/CIRCRESAHA.108.173740
P407
P577
2008-05-09T00:00:00Z