Small-molecule inhibitors of protein-protein interactions: progressing towards the dream - Wikidata - awgldk - TriplyDB

Small-molecule inhibitors of protein-protein interactions: progressing towards the dream

Small-molecule inhibitors of protein-protein interactions: progressing towards the dream

http://www.wikidata.org/entity/Q29617758

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RVX-208, an inducer of ApoA-I in humans, is a BET bromodomain antagonist Cancer genome landscapes Visualization and targeted disruption of protein interactions in living cells Androgen receptor molecular biology and potential targets in prostate cancer Bioluminescence resonance energy transfer (BRET) imaging of protein-protein interactions within deep tissues of living subjects Systematic analysis of helical protein interfaces reveals targets for synthetic inhibitors Virus maturation as a new HIV-1 therapeutic target Critical role for a single leucine residue in leukemia induction by E2A-PBX1 Molecular Mechanisms for cAMP-Mediated Immunoregulation in T cells - Role of Anchored Protein Kinase A Signaling Units Modulation of Protein-Protein Interactions for the Development of Novel Therapeutics Multi-Facial, Non-Peptidic α-Helix Mimetics Targeting protein-protein interactions in complexes organized by A kinase anchoring proteins Molecular docking and structure-based drug design strategies Fine-tuning multiprotein complexes using small molecules Targeting cyclin-dependent kinases in human cancers: from small molecules to Peptide inhibitors Small molecule compounds targeting miRNAs for cancer therapy The growing arsenal of ATP-competitive and allosteric inhibitors of BCR-ABL Expanding the number of 'druggable' targets: non-enzymes and protein-protein interactions Structure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive review Quantification of HER family receptors in breast cancer Proteomic approaches and identification of novel therapeutic targets for alcoholism Small-molecule inhibitors of the Myc oncoprotein Adding diverse noncanonical backbones to rosetta: enabling peptidomimetic design Peptides interfering with protein-protein interactions in the ethylene signaling pathway delay tomato fruit ripening.Targeting protein-protein interactions for parasite control New small molecule inhibitors of hepatitis C virus A surface on the androgen receptor that allosterically regulates coactivator binding Combinatorial Optimization of a CD4-Mimetic Miniprotein and Cocrystal Structures with HIV-1 gp120 Envelope Glycoprotein High-Resolution Structural Characterization of a Helical α/β-Peptide Foldamer Bound to the Anti-Apoptotic Protein Bcl-xL Structural and biological mimicry of protein surface recognition by / -peptide foldamers Limitations of Peptide Retro-inverso Isomerization in Molecular Mimicry A Left-Handed Solution to Peptide Inhibition of the p53-MDM2 Interaction Structural basis for the specific inhibition of heterotrimeric Gq protein by a small molecule Broad Distribution of Energetically Important Contacts across an Extended Protein Interface Discovery, structure-activity relationship studies, and crystal structure of nonpeptide inhibitors bound to the Shank3 PDZ domain Enzyme Inhibition by Allosteric Capture of an Inactive Conformation Structural and Functional Analysis of the Tandem -Zipper Interaction of a Streptococcal Protein with Human Fibronectin Small-Molecule Inhibitors of the Interaction between the E3 Ligase VHL and HIF1α Using a Fragment-Based Approach To Target Protein-Protein Interactions Selective Inhibition of Human Group IIA-secreted Phospholipase A2 (hGIIA) Signaling Reveals Arachidonic Acid Metabolism Is Associated with Colocalization of hGIIA to Vimentin in Rheumatoid Synoviocytes

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Small-molecule inhibitors of protein-protein interactions: progressing towards the dream

http://www.wikidata.org/entity/Q29617758

description

2004 nî lūn-bûn

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2004 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2004 թվականի ապրիլին հրատարակված գիտական հոդված

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2004年の論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年论文

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Small-molecule inhibitors of protein-protein interactions: progressing towards the dream

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Small-molecule inhibitors of protein-protein interactions: progressing towards the dream

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Nature Reviews Drug Discovery

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Small-molecule inhibitors of protein-protein interactions: progressing towards the dream

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Arkin MR

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Wells JA

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P2860

Crystal structure of nerve growth factor in complex with the ligand-binding domain of the TrkA receptor

A Common Mechanism Underlying Promiscuous Inhibitors from Virtual and High-Throughput Screening

Crystal structure of the B7-1/CTLA-4 complex that inhibits human immune responses

Structural plasticity in a remodeled protein-protein interface

Evidence that a protein-protein interaction 'hot spot' on heterotrimeric G protein betagamma subunits is used for recognition of a subclass of effectors

Crystal structure of the I-domain from the CD11a/CD18 (LFA-1, alpha L beta 2) integrin

Modern analytical ultracentrifugation in protein science: a tutorial review

Structural basis for LFA-1 inhibition upon lovastatin binding to the CD11a I-domain

NMR solution structure of the inserted domain of human leukocyte function associated antigen-1

Structure and dimerization of a soluble form of B7-1

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10.1038/NRD1343

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15060526

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