A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation - Wikidata - awgldk - TriplyDB

A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation

A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation

http://www.wikidata.org/entity/Q29618700

about

The CK1 Family: Contribution to Cellular Stress Response and Its Role in Carcinogenesis Ror2 modulates the canonical Wnt signaling in lung epithelial cells through cooperation with Fzd2 Amer1/WTX couples Wnt-induced formation of PtdIns(4,5)P2 to LRP6 phosphorylation R-Spondin1 regulates Wnt signaling by inhibiting internalization of LRP6 The ubiquitin-specific protease USP34 regulates axin stability and Wnt/β-catenin signaling Requirement of prorenin receptor and vacuolar H+-ATPase-mediated acidification for Wnt signaling Protein phosphatase 1 regulates assembly and function of the beta-catenin degradation complex Bcr-Abl stabilizes beta-catenin in chronic myeloid leukemia through its tyrosine phosphorylation Helicobacter pylori-induced activation of beta-catenin involves low density lipoprotein receptor-related protein 6 and Dishevelled Structural and functional characterization of the Wnt inhibitor APC membrane recruitment 1 (Amer1)Transmembrane protein 198 promotes LRP6 phosphorylation and Wnt signaling activation Prostacyclin inhibits non-small cell lung cancer growth by a frizzled 9-dependent pathway that is blocked by secreted frizzled-related protein 1 TBL1-TBLR1 and beta-catenin recruit each other to Wnt target-gene promoter for transcription activation and oncogenesis Caprin-2 enhances canonical Wnt signaling through regulating LRP5/6 phosphorylation Direct inhibition of GSK3beta by the phosphorylated cytoplasmic domain of LRP6 in Wnt/beta-catenin signaling Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation Disabled-2 (Dab2) inhibits Wnt/β-catenin signalling by binding LRP6 and promoting its internalization through clathrin Ligand-dependent ubiquitination of Smad3 is regulated by casein kinase 1 gamma 2, an inhibitor of TGF-beta signaling Inhibition of the Wnt/beta-catenin pathway by the WWOX tumor suppressor protein Glycogen synthase kinase 3: more than a namesake Deubiquitination of Dishevelled by Usp14 is required for Wnt signaling Methylation by protein arginine methyltransferase 1 increases stability of Axin, a negative regulator of Wnt signaling Complement C1q activates canonical Wnt signaling and promotes aging-related phenotypes Wnt/beta-catenin signaling and small molecule inhibitors LGR5 interacts and cointernalizes with Wnt receptors to modulate Wnt/β-catenin signaling Wnt/beta-catenin signaling: components, mechanisms, and diseases Shared molecular mechanisms regulate multiple catenin proteins: canonical Wnt signals and components modulate p120-catenin isoform-1 and additional p120 subfamily members.SUMOylation target sites at the C terminus protect Axin from ubiquitination and confer protein stability Wnt signaling: the good and the bad Axin and GSK3- control Smad3 protein stability and modulate TGF- signaling Targeting Wnt/β-catenin pathway in hepatocellular carcinoma treatment Signaling in Fibrosis: TGF-β, WNT, and YAP/TAZ Converge Keeping Wnt signalosome in check by vesicular traffic Toggling a conformational switch in Wnt/β-catenin signaling: regulation of Axin phosphorylation. The phosphorylation state of Axin controls its scaffold function in two Wnt pathway protein complexes The role of Ryk and Ror receptor tyrosine kinases in Wnt signal transduction Current Understanding on EGFR and Wnt/β-Catenin Signaling in Glioma and Their Possible Crosstalk Targeting the Wnt pathway in human cancers: therapeutic targeting with a focus on OMP-54F28 Frequent loss expression of dab2 and promotor hypermethylation in human cancers: a meta-analysis and systematic review GSK-3 as potential target for therapeutic intervention in cancer Normal morphogenesis of epithelial tissues and progression of epithelial tumors.

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P2860

A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation

http://www.wikidata.org/entity/Q29618700

description

2005 nî lūn-bûn

@nan

2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2005年の論文

@ja

2005年論文

@yue

2005年論文

@zh-hant

2005年論文

@zh-hk

2005年論文

@zh-mo

2005年論文

@zh-tw

2005年论文

@wuu

name

A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation

@ast

A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation

@en

type

label

A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation

@ast

A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation

@en

prefLabel

A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation

@ast

A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation

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A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation

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Heidi Okamura

http://www.w3.org/2001/XMLSchema#string

Keiko Tamai

http://www.w3.org/2001/XMLSchema#string

Raymond Habas

http://www.w3.org/2001/XMLSchema#string

Xi He

http://www.w3.org/2001/XMLSchema#string

Xin Zeng

http://www.w3.org/2001/XMLSchema#string

P2860

LDL-receptor-related proteins in Wnt signal transduction

Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6

GSK-3: tricks of the trade for a multi-tasking kinase

Casein kinase iepsilon in the wnt pathway: regulation of beta-catenin function

Scansite 2.0: Proteome-wide prediction of cell signaling interactions using short sequence motifs

Structure of GSK3beta reveals a primed phosphorylation mechanism

Crystal structure of glycogen synthase kinase 3 beta: structural basis for phosphate-primed substrate specificity and autoinhibition

The Wnt signaling pathway in development and disease

Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism

Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway

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873-877

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scholarly article

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1407583

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10.1038/NATURE04185

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7069

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438

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James R. Woodgett

Bradley W. Doble

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2005-12-01T00:00:00Z

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7428899

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1042641042

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16341017

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phosphorylation

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2100418

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