Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO
about
MAVS recruits multiple ubiquitin E3 ligases to activate antiviral signaling cascadesExpanding the substantial interactome of NEMO using protein microarraysThe IκB kinase complex regulates the stability of cytokine-encoding mRNA induced by TLR-IL-1R by controlling degradation of regnase-1Annexin-1 interacts with NEMO and RIP1 to constitutively activate IKK complex and NF-κB: implication in breast cancer metastasisMalt1 ubiquitination triggers NF-kappaB signaling upon T-cell activationThe signaling adapter p62 is an important mediator of T helper 2 cell function and allergic airway inflammationTRIM40 promotes neddylation of IKKγ and is downregulated in gastrointestinal cancersRetroviral oncoprotein Tax deregulates NF-kappaB by activating Tak1 and mediating the physical association of Tak1-IKKTWEAK induces apoptosis through a death-signaling complex comprising receptor-interacting protein 1 (RIP1), Fas-associated death domain (FADD), and caspase-8RIP1-mediated AIP1 phosphorylation at a 14-3-3-binding site is critical for tumor necrosis factor-induced ASK1-JNK/p38 activationNEMO stabilizes c-Myc through direct interaction in the nucleusThe UBXN1 protein associates with autoubiquitinated forms of the BRCA1 tumor suppressor and inhibits its enzymatic functionUbiquitin binding mediates the NF-kappaB inhibitory potential of ABIN proteinsLIND/ABIN-3 is a novel lipopolysaccharide-inducible inhibitor of NF-kappaB activationRegulation of androgen receptor transcriptional activity and specificity by RNF6-induced ubiquitinationThe ubiquitin-editing enzyme A20 requires RNF11 to downregulate NF-kappaB signallingTrabid, a new positive regulator of Wnt-induced transcription with preference for binding and cleaving K63-linked ubiquitin chainsInvolvement of linear polyubiquitylation of NEMO in NF-kappaB activationMolecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chainsNEMO specifically recognizes K63-linked poly-ubiquitin chains through a new bipartite ubiquitin-binding domainEnhanced binding of TBK1 by an optineurin mutant that causes a familial form of primary open angle glaucomaSite-specific Lys-63-linked tumor necrosis factor receptor-associated factor 6 auto-ubiquitination is a critical determinant of I kappa B kinase activationA novel role for the apoptosis inhibitor ARC in suppressing TNFα-induced regulated necrosisTAK1-dependent signaling requires functional interaction with TAB2/TAB3Direct activation of protein kinases by unanchored polyubiquitin chainsSphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2CARP-2 is an endosome-associated ubiquitin ligase for RIP and regulates TNF-induced NF-kappaB activationPellino3 targets RIP1 and regulates the pro-apoptotic effects of TNF-αcIAP1/2 are direct E3 ligases conjugating diverse types of ubiquitin chains to receptor interacting proteins kinases 1 to 4 (RIP1-4)c-IAP1 and c-IAP2 are critical mediators of tumor necrosis factor alpha (TNFalpha)-induced NF-kappaB activationSam68 is required for both NF-κB activation and apoptosis signaling by the TNF receptorLys63-linked polyubiquitination of IRAK-1 is required for interleukin-1 receptor- and toll-like receptor-mediated NF-kappaB activationA critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-kappaB activationPKC phosphorylation of TRAF2 mediates IKKalpha/beta recruitment and K63-linked polyubiquitinationNEMO recognition of ubiquitinated Bcl10 is required for T cell receptor-mediated NF-kappaB activationABIN-1 is a ubiquitin sensor that restricts cell death and sustains embryonic developmentPellino 3b negatively regulates interleukin-1-induced TAK1-dependent NF kappaB activationThe RING domain and first zinc finger of TRAF6 coordinate signaling by interleukin-1, lipopolysaccharide, and RANKLAtypical ubiquitin chains: new molecular signals. 'Protein Modifications: Beyond the Usual Suspects' review seriesInterleukin-1 (IL-1) induces the Lys63-linked polyubiquitination of IL-1 receptor-associated kinase 1 to facilitate NEMO binding and the activation of IkappaBalpha kinase
P2860
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P2860
Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO
description
2006 nî lūn-bûn
@nan
2006 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Activation of IKK by TNFalpha ...... polyubiquitin binding by NEMO
@ast
Activation of IKK by TNFalpha ...... polyubiquitin binding by NEMO
@en
type
label
Activation of IKK by TNFalpha ...... polyubiquitin binding by NEMO
@ast
Activation of IKK by TNFalpha ...... polyubiquitin binding by NEMO
@en
prefLabel
Activation of IKK by TNFalpha ...... polyubiquitin binding by NEMO
@ast
Activation of IKK by TNFalpha ...... polyubiquitin binding by NEMO
@en
P2093
P3181
P1433
P1476
Activation of IKK by TNFalpha ...... polyubiquitin binding by NEMO
@en
P2093
P304
P3181
P356
10.1016/J.MOLCEL.2006.03.026
P407
P577
2006-04-21T00:00:00Z