Comparative anatomy of the aldo-keto reductase superfamily
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Cloning and sequencing of the cDNA species for mammalian dimeric dihydrodiol dehydrogenasesAldo-keto reductase 1C3 is expressed in differentiated human epidermis, affects keratinocyte differentiation, and is upregulated in atopic dermatitisParkinsonism-associated protein DJ-1/Park7 is a major protein deglycase that repairs methylglyoxal- and glyoxal-glycated cysteine, arginine, and lysine residuesIdentification and characterization of a novel human aldose reductase-like geneTissue distribution of human AKR1C3 and rat homolog in the adult genitourinary systemHuman aldose reductase and human small intestine aldose reductase are efficient retinal reductases: consequences for retinoid metabolismExpanded substrate screenings of human and Drosophila type 10 17beta-hydroxysteroid dehydrogenases (HSDs) reveal multiple specificities in bile acid and steroid hormone metabolism: characterization of multifunctional 3alpha/7alpha/7beta/17beta/20betMajor differences exist in the function and tissue-specific expression of human aflatoxin B1 aldehyde reductase and the principal human aldo-keto reductase AKR1 family membersHuman 3alpha-hydroxysteroid dehydrogenase isoforms (AKR1C1-AKR1C4) of the aldo-keto reductase superfamily: functional plasticity and tissue distribution reveals roles in the inactivation and formation of male and female sex hormonesIdentification of the yqhE and yafB genes encoding two 2, 5-diketo-D-gluconate reductases in Escherichia coliPlant tropane alkaloid biosynthesis evolved independently in the Solanaceae and ErythroxylaceaeSelective serotonin reuptake inhibitors directly alter activity of neurosteroidogenic enzymesInhibition of human steroid 5beta-reductase (AKR1D1) by finasteride and structure of the enzyme-inhibitor complexActivity and expression of progesterone metabolizing 5alpha-reductase, 20alpha-hydroxysteroid oxidoreductase and 3alpha(beta)-hydroxysteroid oxidoreductases in tumorigenic (MCF-7, MDA-MB-231, T-47D) and nontumorigenic (MCF-10A) human breast cancer cFundamental roles of reactive oxygen species and protective mechanisms in the female reproductive systemThe crystal structure of rat liver AKR7A1. A dimeric member of the aldo-keto reductase superfamilyStructure-based inhibitor design for an enzyme that binds different steroids: a potent inhibitor for human type 5 17beta-hydroxysteroid dehydrogenaseStructure of 3(17)α-hydroxysteroid dehydrogenase (AKR1C21) holoenzyme from an orthorhombic crystal form: an insight into the bifunctionality of the enzymeBarley aldose reductase: structure, cofactor binding, and substrate recognition in the aldo/keto reductase 4C familyCrystal Structure of Human Liver 4-3-Ketosteroid 5 -Reductase (AKR1D1) and Implications for Substrate Binding and CatalysisStructure and catalytic mechanism of human steroid 5β-reductase (AKR1D1)Crystal Structure of Perakine Reductase, Founding Member of a Novel Aldo-Keto Reductase (AKR) Subfamily That Undergoes Unique Conformational Changes during NADPH BindingMacro-to-Micro Structural Proteomics: Native Source Proteins for High-Throughput CrystallizationConversion of Human Steroid 5 -Reductase (AKR1D1) into 3 -Hydroxysteroid Dehydrogenase by Single Point Mutation E120H: EXAMPLE OF PERFECT ENZYME ENGINEERINGStructure of the His269Arg mutant of the rat aldose reductase-like protein AKR1B14 complexed with NADPHStructures ofSaccharomyces cerevisiaeD-arabinose dehydrogenase Ara1 and its complex with NADPH: implications for cofactor-assisted substrate recognitionStructure of conjugated polyketone reductase from Candida parapsilosis IFO 0708 reveals conformational changes for substrate recognition upon NADPH bindingCrystal structure of 2,5-diketo-D-gluconic acid reductase A complexed with NADPH at 2.1-A resolutionTropane and Granatane Alkaloid Biosynthesis: A Systematic AnalysisAldo-Keto Reductases 1B in Adrenal Cortex PhysiologycDNA cloning, expression and characterization of human prostaglandin F synthaseClose kinship of human 20alpha-hydroxysteroid dehydrogenase gene with three aldo-keto reductase genesCrystal structures of Delta1-piperideine-2-carboxylate/Delta1-pyrroline-2-carboxylate reductase belonging to a new family of NAD(P)H-dependent oxidoreductases: conformational change, substrate recognition, and stereochemistry of the reactionMinimalist active-site redesign: teaching old enzymes new tricksConversion of mammalian 3alpha-hydroxysteroid dehydrogenase to 20alpha-hydroxysteroid dehydrogenase using loop chimeras: changing specificity from androgens to progestinsPlasmid-encoded phthalate catabolic pathway in Arthrobacter keyseri 12BAldose reductase regulates TGF-beta1-induced production of fibronectin and type IV collagen in cultured rat mesangial cellsCatalytic mechanism and substrate specificity of the beta-subunit of the voltage-gated potassium channelAnatomical and cellular localization of neuroactive 5 alpha/3 alpha-reduced steroid-synthesizing enzymes in the spinal cordCloning and characterization of two novel aldo-keto reductases (AKR1C12 and AKR1C13) from mouse stomach
P2860
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P2860
Comparative anatomy of the aldo-keto reductase superfamily
description
1997 nî lūn-bûn
@nan
1997 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Comparative anatomy of the aldo-keto reductase superfamily
@ast
Comparative anatomy of the aldo-keto reductase superfamily
@en
type
label
Comparative anatomy of the aldo-keto reductase superfamily
@ast
Comparative anatomy of the aldo-keto reductase superfamily
@en
prefLabel
Comparative anatomy of the aldo-keto reductase superfamily
@ast
Comparative anatomy of the aldo-keto reductase superfamily
@en
P2093
P2860
P3181
P356
P1433
P1476
Comparative anatomy of the aldo-keto reductase superfamily
@en
P2093
P2860
P304
P3181
P356
10.1042/BJ3260625
P407
P478
326 ( Pt 3)
P577
1997-09-15T00:00:00Z