Structure and function analysis of the CMS/CIN85 protein family identifies actin-bundling properties and heterotypic-complex formation.
about
CIN85 regulates dopamine receptor endocytosis and governs behaviour in miceCapping protein regulators fine-tune actin assembly dynamicsMembrane trafficking in podocyte health and diseaseThe adaptor protein CIN85 assembles intracellular signaling clusters for B cell activationDifferential Recognition Preferences of the Three Src Homology 3 (SH3) Domains from the Adaptor CD2-associated Protein (CD2AP) and Direct Association with Ras and Rab Interactor 3 (RIN3).Effects of CD2-associated protein deficiency on amyloid-β in neuroblastoma cells and in an APP transgenic mouse model.Inhibition of CIN85-mediated invasion by a novel SH3 domain binding motif in the lysyl oxidase propeptide.Proteins recruited by SH3 domains of Ruk/CIN85 adaptor identified by LC-MS/MS.Podosomes and Invadopodia: Related structures with Common Protein Components that May Promote Breast Cancer Cellular Invasion.Clioquinol promotes the degradation of metal-dependent amyloid-β (Aβ) oligomers to restore endocytosis and ameliorate Aβ toxicity.Structural characterization of a capping protein interaction motif defines a family of actin filament regulators.Functional links between Aβ toxicity, endocytic trafficking, and Alzheimer's disease risk factors in yeast.CD2AP regulates SUMOylation of CIN85 in podocytes.Novel Host Proteins and Signaling Pathways in Enteropathogenic E. coli Pathogenesis Identified by Global Phosphoproteome Analysis.The Drosophila CD2AP/CIN85 orthologue Cindr regulates junctions and cytoskeleton dynamics during tissue patterningExome Sequencing Identifies Pathogenic and Modifier Mutations in a Child With Sporadic Dilated Cardiomyopathy.FSGS3/CD2AP is a barbed-end capping protein that stabilizes actin and strengthens adherens junctions.Endocytic Trafficking at the Mature Podocyte Slit Diaphragm.Endothelial CD2AP Binds the Receptor ICAM-1 To Control Mechanosignaling, Leukocyte Adhesion, and the Route of Leukocyte Diapedesis In Vitro.CIN85/RukL is a novel binding partner of nephrin and podocin and mediates slit diaphragm turnover in podocytesCIN85 associates with endosomal membrane and binds phosphatidic acid.CD2-associated protein regulates plasmacytoid dendritic cell migration, but is dispensable for their development and cytokine production.The binding stoichiometry of CIN85 SH3 domain A and cbl-b.TAGLN2 polymerizes G-actin in a low ionic state but blocks Arp2/3-nucleated actin branching in physiological conditions.Mutation of CD2AP and SH3KBP1 Binding Motif in Alphavirus nsP3 Hypervariable Domain Results in Attenuated Virus.
P2860
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P2860
Structure and function analysis of the CMS/CIN85 protein family identifies actin-bundling properties and heterotypic-complex formation.
description
2007 nî lūn-bûn
@nan
2007 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Structure and function analysi ...... heterotypic-complex formation.
@ast
Structure and function analysi ...... heterotypic-complex formation.
@en
type
label
Structure and function analysi ...... heterotypic-complex formation.
@ast
Structure and function analysi ...... heterotypic-complex formation.
@en
prefLabel
Structure and function analysi ...... heterotypic-complex formation.
@ast
Structure and function analysi ...... heterotypic-complex formation.
@en
P2093
P356
P1476
Structure and function analysi ...... heterotypic-complex formation
@en
P2093
Duane J Oswald
Gabriel Gaidos
Paul A Toselli
Shefali Soni
P304
P356
10.1242/JCS.004333
P407
P577
2007-07-01T00:00:00Z