Determinants of intra versus intermolecular self-association within the regulatory domains of Rlk and Itk.
about
Crystal structure of a rigid four-spectrin-repeat fragment of the human desmoplakin plakin domainDynamics of the Tec-family tyrosine kinase SH3 domains.Development and Application of a High Throughput Protein Unfolding Kinetic AssaySH2-dependent autophosphorylation within the Tec family kinase Itk.Proline isomerization preorganizes the Itk SH2 domain for binding to the Itk SH3 domain.Mechanism and functional significance of Itk autophosphorylation.Quantitative relation between intermolecular and intramolecular binding of pro-rich peptides to SH3 domains.SHIP family inositol phosphatases interact with and negatively regulate the Tec tyrosine kinase.Murine Itk SH3 domainT-cell signaling regulated by the Tec family kinase, Itk.Disrupting the intermolecular self-association of Itk enhances T cell signaling.In silico modeling of Itk activation kinetics in thymocytes suggests competing positive and negative IP4 mediated feedbacks increase robustness.Conformational snapshots of Tec kinases during signaling.ITK inhibitors in inflammation and immune-mediated disorders.Structure and function of Tec family kinase Itk.Achieving a Graded Immune Response: BTK Adopts a Range of Active/Inactive Conformations Dictated by Multiple Interdomain Contacts.Regulation of Hematopoietic Cell Development and Function Through Phosphoinositides.
P2860
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P2860
Determinants of intra versus intermolecular self-association within the regulatory domains of Rlk and Itk.
description
2003 nî lūn-bûn
@nan
2003 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Determinants of intra versus i ...... latory domains of Rlk and Itk.
@ast
Determinants of intra versus i ...... latory domains of Rlk and Itk.
@en
type
label
Determinants of intra versus i ...... latory domains of Rlk and Itk.
@ast
Determinants of intra versus i ...... latory domains of Rlk and Itk.
@en
prefLabel
Determinants of intra versus i ...... latory domains of Rlk and Itk.
@ast
Determinants of intra versus i ...... latory domains of Rlk and Itk.
@en
P2093
P1476
Determinants of intra versus i ...... latory domains of Rlk and Itk.
@en
P2093
Amy H Andreotti
D Bruce Fulton
Kendall W Cradic
P304
P356
10.1016/S0022-2836(03)00531-X
P407
P577
2003-06-01T00:00:00Z