Mechanism and functional significance of Itk autophosphorylation. - Wikidata - awgldk - TriplyDB

Mechanism and functional significance of Itk autophosphorylation.

Mechanism and functional significance of Itk autophosphorylation.

http://www.wikidata.org/entity/Q30157748

about

SH3 domain tyrosine phosphorylation--sites, role and evolution.Tyrosine phosphorylation within the SH3 domain regulates CAS subcellular localization, cell migration, and invasiveness SH2-dependent autophosphorylation within the Tec family kinase Itk.Proline isomerization preorganizes the Itk SH2 domain for binding to the Itk SH3 domain.T-cell signaling regulated by the Tec family kinase, Itk.Disrupting the intermolecular self-association of Itk enhances T cell signaling.Scaffold Protein SLP-76 Primes PLCγ1 for Activation by ITK-Mediated Phosphorylation.Conformational snapshots of Tec kinases during signaling.Itk tyrosine kinase substrate docking is mediated by a nonclassical SH2 domain surface of PLCgamma1.Targeting Interleukin-2-Inducible T-cell Kinase (ITK) in T-Cell Related Diseases.ITK inhibitors in inflammation and immune-mediated disorders.Structure and function of Tec family kinase Itk.

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Mechanism and functional significance of Itk autophosphorylation.

http://www.wikidata.org/entity/Q30157748

description

2007 nî lūn-bûn

@nan

2007 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2007年の論文

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2007年論文

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2007年論文

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2007年論文

@zh-hk

2007年論文

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2007年論文

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2007年论文

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name

Mechanism and functional significance of Itk autophosphorylation.

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Mechanism and functional significance of Itk autophosphorylation.

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type

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Mechanism and functional significance of Itk autophosphorylation.

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Mechanism and functional significance of Itk autophosphorylation.

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Mechanism and functional significance of Itk autophosphorylation.

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Mechanism and functional significance of Itk autophosphorylation.

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J.JMB.2007.08.060

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Journal of Molecular Biology

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Mechanism and functional significance of Itk autophosphorylation.

@en

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Amy H Andreotti

http://www.w3.org/2001/XMLSchema#string

D Bruce Fulton

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Raji E Joseph

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P2860

LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation

BAP-135, a target for Bruton's tyrosine kinase in response to B cell receptor engagement

The solution structure and intramolecular associations of the Tec kinase SRC homology 3 domain

Structure of the carboxyl-terminal Src kinase, Csk

Structural characterization of a proline-driven conformational switch within the Itk SH2 domain

Crystal structures of interleukin-2 tyrosine kinase and their implications for the design of selective inhibitors

Regulatory intramolecular association in a tyrosine kinase of the Tec family

Three-dimensional structure of the tyrosine kinase c-Src

Solution structure of the SH3 domain from Bruton's tyrosine kinase

Biochemical interactions integrating Itk with the T cell receptor-initiated signaling cascade

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1281-1292

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scholarly article

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10.1016/J.JMB.2007.08.060

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2007-08-31T00:00:00Z

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